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Article: A prospective evaluation of preoperative localization by technetium-99m sestamibi scintigraphy and ultrasonography in primary hyperparathyroidism

TitleA prospective evaluation of preoperative localization by technetium-99m sestamibi scintigraphy and ultrasonography in primary hyperparathyroidism
Authors
KeywordsMinimally invasive parathyroidectomy
Parathyroid adenoma
Primary hyperparathyroidism
Tc99m-Sestamibi scintigraphy
Ultrasonography
Issue Date2007
PublisherElsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/amjsurg
Citation
American Journal Of Surgery, 2007, v. 193 n. 2, p. 155-159 How to Cite?
AbstractBackground: Ultrasonography (USG) and technetium-99m sestamibi (MIBI) scintigraphy are commonly used imaging modalities in the era of minimally invasive parathyroidectomy (MIP) for primary hyperparathyroidism (pHPT). However, their relative importance and actual contribution to MIP have not been prospectively assessed. Methods: A total of 100 consecutive pHPT patients planning for MIP were recruited. Both USG and MIBI findings were correlated with intraoperative findings and postoperative outcome. Clinicopathologic factors were examined for potential association with a correct localizing result. Results: Thirty men and 70 women (age range 13 to 93 years [median 55.5]) were included in the study. The final pathology included 98 patients with solitary adenoma and 2 patients with multiglandular disease. The sensitivities, accuracies, and positive predicted values for USG and MIBI alone were 57% vs 89%, 56% vs 85%, and 97% vs 94%, respectively. Correctly localized adenomas were significantly heavier than incorrectly localized ones. Conclusions: MIBI is preferred over USG in pHPT patients planning for MIP. Weight of adenoma appeared to be the only clinicopathologic factor determining localization accuracy. © 2007 Excerpta Medica Inc. All rights reserved.
Persistent Identifierhttp://hdl.handle.net/10722/76534
ISSN
2015 Impact Factor: 2.403
2015 SCImago Journal Rankings: 1.286
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorLo, CYen_HK
dc.contributor.authorLang, BHen_HK
dc.contributor.authorChan, WFen_HK
dc.contributor.authorKung, AWCen_HK
dc.contributor.authorLam, KSLen_HK
dc.date.accessioned2010-09-06T07:22:15Z-
dc.date.available2010-09-06T07:22:15Z-
dc.date.issued2007en_HK
dc.identifier.citationAmerican Journal Of Surgery, 2007, v. 193 n. 2, p. 155-159en_HK
dc.identifier.issn0002-9610en_HK
dc.identifier.urihttp://hdl.handle.net/10722/76534-
dc.description.abstractBackground: Ultrasonography (USG) and technetium-99m sestamibi (MIBI) scintigraphy are commonly used imaging modalities in the era of minimally invasive parathyroidectomy (MIP) for primary hyperparathyroidism (pHPT). However, their relative importance and actual contribution to MIP have not been prospectively assessed. Methods: A total of 100 consecutive pHPT patients planning for MIP were recruited. Both USG and MIBI findings were correlated with intraoperative findings and postoperative outcome. Clinicopathologic factors were examined for potential association with a correct localizing result. Results: Thirty men and 70 women (age range 13 to 93 years [median 55.5]) were included in the study. The final pathology included 98 patients with solitary adenoma and 2 patients with multiglandular disease. The sensitivities, accuracies, and positive predicted values for USG and MIBI alone were 57% vs 89%, 56% vs 85%, and 97% vs 94%, respectively. Correctly localized adenomas were significantly heavier than incorrectly localized ones. Conclusions: MIBI is preferred over USG in pHPT patients planning for MIP. Weight of adenoma appeared to be the only clinicopathologic factor determining localization accuracy. © 2007 Excerpta Medica Inc. All rights reserved.en_HK
dc.languageengen_HK
dc.publisherElsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/amjsurgen_HK
dc.relation.ispartofAmerican Journal of Surgeryen_HK
dc.rightsNOTICE: this is the author’s version of a work that was accepted for publication in <Journal title>. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in PUBLICATION, [VOL#, ISSUE#, (DATE)] DOI#en_HK
dc.subjectMinimally invasive parathyroidectomyen_HK
dc.subjectParathyroid adenomaen_HK
dc.subjectPrimary hyperparathyroidismen_HK
dc.subjectTc99m-Sestamibi scintigraphyen_HK
dc.subjectUltrasonographyen_HK
dc.subject.meshAdenoma - radionuclide imaging - surgery - ultrasonography-
dc.subject.meshHyperparathyroidism, Primary - etiology-
dc.subject.meshHyperplasia-
dc.subject.meshParathyroid Neoplasms - radionuclide imaging - surgery - ultrasonography-
dc.subject.meshTechnetium Tc 99m Sestamibi-
dc.titleA prospective evaluation of preoperative localization by technetium-99m sestamibi scintigraphy and ultrasonography in primary hyperparathyroidismen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0002-9610&volume=193&issue=2&spage=155&epage=159&date=2007&atitle=A+prospective+evaluation+of+preoperative+localization+by+technetium-99m+sestamibi+scintigraphy+and+ultrasonography+in+primary+hyperparathyroidism+en_HK
dc.identifier.emailKung, AWC:awckung@hku.hken_HK
dc.identifier.emailLam, KSL:ksllam@hku.hken_HK
dc.identifier.authorityKung, AWC=rp00368en_HK
dc.identifier.authorityLam, KSL=rp00343en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1016/j.amjsurg.2006.04.020en_HK
dc.identifier.pmid17236840-
dc.identifier.scopuseid_2-s2.0-33846229145en_HK
dc.identifier.hkuros226722en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-33846229145&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume193en_HK
dc.identifier.issue2en_HK
dc.identifier.spage155en_HK
dc.identifier.epage159en_HK
dc.identifier.isiWOS:000243923400003-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridLo, CY=16417392800en_HK
dc.identifier.scopusauthoridLang, BH=7201907327en_HK
dc.identifier.scopusauthoridChan, WF=7403918455en_HK
dc.identifier.scopusauthoridKung, AWC=7102322339en_HK
dc.identifier.scopusauthoridLam, KSL=8082870600en_HK

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