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- Publisher Website: 10.1186/1742-4690-6-78
- Scopus: eid_2-s2.0-70349921798
- PMID: 19712452
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Article: SiRNA and shRNA screens advance key understanding of host factors required for HIV-1 replication
Title | SiRNA and shRNA screens advance key understanding of host factors required for HIV-1 replication |
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Authors | |
Issue Date | 2009 |
Publisher | BioMed Central Ltd. The Journal's web site is located at http://www.retrovirology.com/home/ |
Citation | Retrovirology, 2009, v. 6, p. 78 How to Cite? |
Abstract | A recent RNAi screen used a genome-wide shRNA library to search for cellular factors required for HIV-1 replication. This work complements three other siRNA-based screening studies and potentially opens the door to the discovery of factors that are important for HIV-1 replication in physiological host cells such as T lymphocytes. shRNA screens can be further improved, and they could promise to unravel new pathways and new facets of virus-cell interactions. © 2009 Kok et al; licensee BioMed Central Ltd. |
Persistent Identifier | http://hdl.handle.net/10722/68211 |
ISSN | 2021 Impact Factor: 3.768 2020 SCImago Journal Rankings: 2.126 |
PubMed Central ID | |
ISI Accession Number ID | |
References |
DC Field | Value | Language |
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dc.contributor.author | Kok, KH | en_HK |
dc.contributor.author | Lei, T | en_HK |
dc.contributor.author | Jin, DY | en_HK |
dc.date.accessioned | 2010-09-06T06:02:25Z | - |
dc.date.available | 2010-09-06T06:02:25Z | - |
dc.date.issued | 2009 | en_HK |
dc.identifier.citation | Retrovirology, 2009, v. 6, p. 78 | en_HK |
dc.identifier.issn | 1742-4690 | en_HK |
dc.identifier.uri | http://hdl.handle.net/10722/68211 | - |
dc.description.abstract | A recent RNAi screen used a genome-wide shRNA library to search for cellular factors required for HIV-1 replication. This work complements three other siRNA-based screening studies and potentially opens the door to the discovery of factors that are important for HIV-1 replication in physiological host cells such as T lymphocytes. shRNA screens can be further improved, and they could promise to unravel new pathways and new facets of virus-cell interactions. © 2009 Kok et al; licensee BioMed Central Ltd. | en_HK |
dc.language | eng | en_HK |
dc.publisher | BioMed Central Ltd. The Journal's web site is located at http://www.retrovirology.com/home/ | en_HK |
dc.relation.ispartof | Retrovirology | en_HK |
dc.rights | This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. | - |
dc.rights | Retrovirology. Copyright © BioMed Central Ltd. | en_HK |
dc.subject.mesh | Cell Line | - |
dc.subject.mesh | Gene Knockdown Techniques | - |
dc.subject.mesh | HIV-1 - physiology | - |
dc.subject.mesh | Host-Pathogen Interactions | - |
dc.subject.mesh | Virus Replication | - |
dc.title | SiRNA and shRNA screens advance key understanding of host factors required for HIV-1 replication | en_HK |
dc.type | Article | en_HK |
dc.identifier.openurl | http://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1742-4690&volume=6&spage=78&epage=&date=2009&atitle=siRNA+and+shRNA+screens+advance+key+understanding+of+host+factors+required+for+HIV-1+replication | en_HK |
dc.identifier.email | Kok, KH:khkok@hku.hk | en_HK |
dc.identifier.email | Jin, DY:dyjin@hkucc.hku.hk | en_HK |
dc.identifier.authority | Kok, KH=rp01455 | en_HK |
dc.identifier.authority | Jin, DY=rp00452 | en_HK |
dc.description.nature | published_or_final_version | - |
dc.identifier.doi | 10.1186/1742-4690-6-78 | en_HK |
dc.identifier.pmid | 19712452 | - |
dc.identifier.pmcid | PMC2743632 | - |
dc.identifier.scopus | eid_2-s2.0-70349921798 | en_HK |
dc.identifier.hkuros | 166469 | en_HK |
dc.relation.references | http://www.scopus.com/mlt/select.url?eid=2-s2.0-70349921798&selection=ref&src=s&origin=recordpage | en_HK |
dc.identifier.volume | 6 | en_HK |
dc.identifier.spage | 78 | en_HK |
dc.identifier.epage | 78 | en_HK |
dc.identifier.isi | WOS:000270145700001 | - |
dc.publisher.place | United Kingdom | en_HK |
dc.identifier.scopusauthorid | Kok, KH=7006862631 | en_HK |
dc.identifier.scopusauthorid | Lei, T=35194438500 | en_HK |
dc.identifier.scopusauthorid | Jin, DY=7201973614 | en_HK |
dc.identifier.citeulike | 5660179 | - |
dc.identifier.issnl | 1742-4690 | - |