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Conference Paper: The first three years of pharmacotherapy in patients with psychotic disorders: a comparison between the early intervention programme and standard care service in Hong Kong

TitleThe first three years of pharmacotherapy in patients with psychotic disorders: a comparison between the early intervention programme and standard care service in Hong Kong
Authors
Issue Date2009
PublisherOxford University Press. The Journal's web site is located at http://schizophreniabulletin.oxfordjournals.org/
Citation
The 12th International Congress on Schizophrenia Research (ICOSR 2009), San Diego, CA., 28 March-1 April 2009. In Schizophrenia Bulletin, 2009, v. 35 suppl 1, p. 132 How to Cite?
AbstractThis naturalistic study reviews the use of antipsychotics in patients with psychotic disorders in the first three years of psychiatric treatment. This historical-controlled study included 700 patients first presented to the local early intervention programme (EI) from 2001 to 2003, and 700 patients first presented to standard care service (SC) from 1998 to 2001. The data were systematically extracted from medical records according to operationalized definitions. In the EI group, 22.2% of cases were prescribed atypical antipsychotics as the initial pharmacotherapy, which increased to 59.4% and 58.7% in the first and second switches of antipsychotics respectively. Respective statistics in the SC group (6.3%, 19.5% and 23.4%, all p-value <.001) were significantly lower than the EI group. In EI, the three most frequently prescribed antipsychotics in initial treatment were conventionals: haloperidol (28.6%), trifluoperazine (23.7%) and sulpiride (14.5%). First switch of antipsychotics was mainly risperidone (22.0%), olanzapine (19.3%) and sulpiride (11.1%). Second switch of antipsychotics was mainly to olanzapine (19.9%), risperidone (13.6%) and sulpiride (10.7%). In SC, the three most frequently prescribed antipsychotics in the initial treatment were haloperidol (32.1%), trifluoperazine (26.6%) and chlorpromazine (12.7%). First switch of antipsychotics were mainly conventional antipsychotics, which were trifluoperazine (15.3%), sulpiride (15.0%) and chlorpromazine (11.1%). The second switch of antipsychotics was similar to the first switch: sulpiride (16.9%), chlorpromazine (14.9%) and trifluoperazine (12.9%). In the first three years of psychiatric treatment, the findings revealed that early intervention programme in Hong Kong had a different practice in prescribing antipsychotics. Atypical antipsychotics were more widespread in use in the EI group while conventional antipsychotics remained to be the major pharmacotherapy in the SC group.
DescriptionSession - 9. 9. Health Economics and Services Research
Abstracts for the 12th International Congress on Schizophrenia Research (ICOSR)
Persistent Identifierhttp://hdl.handle.net/10722/62685
ISSN
2015 Impact Factor: 7.757
2015 SCImago Journal Rankings: 4.051
PubMed Central ID
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorTang, JYMen_HK
dc.contributor.authorChen, EYHen_HK
dc.contributor.authorHui, CLMen_HK
dc.contributor.authorLaw, CWen_HK
dc.contributor.authorYew, Cen_HK
dc.contributor.authorWong, GHYen_HK
dc.contributor.authorChung, DWSen_HK
dc.contributor.authorChiu, CPYen_HK
dc.contributor.authorLam, MLM-
dc.contributor.authorTso, S-
dc.contributor.authorChan, K-
dc.contributor.authorYip, KC-
dc.contributor.authorHung, SF-
dc.contributor.authorTay, M-
dc.date.accessioned2010-07-13T04:06:50Z-
dc.date.available2010-07-13T04:06:50Z-
dc.date.issued2009en_HK
dc.identifier.citationThe 12th International Congress on Schizophrenia Research (ICOSR 2009), San Diego, CA., 28 March-1 April 2009. In Schizophrenia Bulletin, 2009, v. 35 suppl 1, p. 132en_HK
dc.identifier.issn0586-7614en_HK
dc.identifier.urihttp://hdl.handle.net/10722/62685-
dc.descriptionSession - 9. 9. Health Economics and Services Researchen_HK
dc.descriptionAbstracts for the 12th International Congress on Schizophrenia Research (ICOSR)-
dc.description.abstractThis naturalistic study reviews the use of antipsychotics in patients with psychotic disorders in the first three years of psychiatric treatment. This historical-controlled study included 700 patients first presented to the local early intervention programme (EI) from 2001 to 2003, and 700 patients first presented to standard care service (SC) from 1998 to 2001. The data were systematically extracted from medical records according to operationalized definitions. In the EI group, 22.2% of cases were prescribed atypical antipsychotics as the initial pharmacotherapy, which increased to 59.4% and 58.7% in the first and second switches of antipsychotics respectively. Respective statistics in the SC group (6.3%, 19.5% and 23.4%, all p-value <.001) were significantly lower than the EI group. In EI, the three most frequently prescribed antipsychotics in initial treatment were conventionals: haloperidol (28.6%), trifluoperazine (23.7%) and sulpiride (14.5%). First switch of antipsychotics was mainly risperidone (22.0%), olanzapine (19.3%) and sulpiride (11.1%). Second switch of antipsychotics was mainly to olanzapine (19.9%), risperidone (13.6%) and sulpiride (10.7%). In SC, the three most frequently prescribed antipsychotics in the initial treatment were haloperidol (32.1%), trifluoperazine (26.6%) and chlorpromazine (12.7%). First switch of antipsychotics were mainly conventional antipsychotics, which were trifluoperazine (15.3%), sulpiride (15.0%) and chlorpromazine (11.1%). The second switch of antipsychotics was similar to the first switch: sulpiride (16.9%), chlorpromazine (14.9%) and trifluoperazine (12.9%). In the first three years of psychiatric treatment, the findings revealed that early intervention programme in Hong Kong had a different practice in prescribing antipsychotics. Atypical antipsychotics were more widespread in use in the EI group while conventional antipsychotics remained to be the major pharmacotherapy in the SC group.-
dc.languageengen_HK
dc.publisherOxford University Press. The Journal's web site is located at http://schizophreniabulletin.oxfordjournals.org/en_HK
dc.relation.ispartofSchizophrenia Bulletin-
dc.titleThe first three years of pharmacotherapy in patients with psychotic disorders: a comparison between the early intervention programme and standard care service in Hong Kongen_HK
dc.typeConference_Paperen_HK
dc.identifier.emailTang, JYM: jennitym@yahoo.com.hken_HK
dc.identifier.emailChen, EYH: eyhchen@hku.hken_HK
dc.identifier.emailHui, CLM: clmhui@hku.hken_HK
dc.identifier.emailWong, GHY: ghywong@hku.hken_HK
dc.identifier.emailChiu, CPY: chiupyc@hku.hken_HK
dc.identifier.emailLam, MLM: maylam11@hku.hken_HK
dc.identifier.authorityChen, EYH=rp00392en_HK
dc.identifier.authorityWong, GHY=rp01850en_HK
dc.description.naturelink_to_OA_fulltext-
dc.identifier.doi10.1093/schbul/sbn173-
dc.identifier.pmid19252181-
dc.identifier.pmcidPMC2651108-
dc.identifier.hkuros163064en_HK
dc.identifier.volume35-
dc.identifier.issuesuppl. 1-
dc.identifier.spage132-
dc.identifier.epage132-
dc.identifier.isiWOS:000263964700003-
dc.publisher.placeUnited Kingdom-

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