File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)
Supplementary

Article: Gestational trophoblastic disease

TitleGestational trophoblastic disease
Authors
Keywordschoriocarcinoma
epithelioid trophoblastc tumour
gestational trophoblastic disease
hydatidiform mole
placental site trophoblastic tumour
Issue Date2009
PublisherElsevier Ltd
Citation
Obstetrics, Gynaecology And Reproductive Medicine, 2009, v. 19 n. 4, p. 89-97 How to Cite?
AbstractGestational trophoblastic disease is a rare pregnancy-related disorder and its incidence is about 1 in 1000 livebirths in the West. It comprises of partial mole, complete mole, invasive and metastatic mole, choriocarcinoma, placental site trophoblastic tumour and epithelioid trophoblastic tumour. Novel immunohistochemical technologies have helped in the diagnosis of the disease and some of the genes may also serve as prognostic markers. Partial and complete moles can be treated by suction evacuation and most patients do not require further treatment. However, 10-20% of them may develop gestational trophoblastic neoplasia. The Gynecological Oncology Committee has adopted a staging system with incorporation of the modified World Health Organization scoring system. Low-risk disease is treated by single-agent chemotherapy while high-risk disease is treated by multi-agent chemotherapy. The overall cure rate is more than 90% and most patients can preserve fertility and anticipate normal pregnancy outcomes. Nevertheless, the disease can recur. Referral to a specialist centre is important to ensure proper monitoring and management. © 2008 Elsevier Ltd. All rights reserved.
Persistent Identifierhttp://hdl.handle.net/10722/60389
ISSN
2015 SCImago Journal Rankings: 0.158

 

DC FieldValueLanguage
dc.contributor.authorTse, KYen_HK
dc.contributor.authorChan, KKLen_HK
dc.contributor.authorTam, KFen_HK
dc.contributor.authorNgan, HYSen_HK
dc.date.accessioned2010-05-31T04:09:39Z-
dc.date.available2010-05-31T04:09:39Z-
dc.date.issued2009en_HK
dc.identifier.citationObstetrics, Gynaecology And Reproductive Medicine, 2009, v. 19 n. 4, p. 89-97en_HK
dc.identifier.issn1751-7214en_HK
dc.identifier.urihttp://hdl.handle.net/10722/60389-
dc.description.abstractGestational trophoblastic disease is a rare pregnancy-related disorder and its incidence is about 1 in 1000 livebirths in the West. It comprises of partial mole, complete mole, invasive and metastatic mole, choriocarcinoma, placental site trophoblastic tumour and epithelioid trophoblastic tumour. Novel immunohistochemical technologies have helped in the diagnosis of the disease and some of the genes may also serve as prognostic markers. Partial and complete moles can be treated by suction evacuation and most patients do not require further treatment. However, 10-20% of them may develop gestational trophoblastic neoplasia. The Gynecological Oncology Committee has adopted a staging system with incorporation of the modified World Health Organization scoring system. Low-risk disease is treated by single-agent chemotherapy while high-risk disease is treated by multi-agent chemotherapy. The overall cure rate is more than 90% and most patients can preserve fertility and anticipate normal pregnancy outcomes. Nevertheless, the disease can recur. Referral to a specialist centre is important to ensure proper monitoring and management. © 2008 Elsevier Ltd. All rights reserved.en_HK
dc.languageengen_HK
dc.publisherElsevier Ltden_HK
dc.relation.ispartofObstetrics, Gynaecology and Reproductive Medicineen_HK
dc.subjectchoriocarcinomaen_HK
dc.subjectepithelioid trophoblastc tumouren_HK
dc.subjectgestational trophoblastic diseaseen_HK
dc.subjecthydatidiform moleen_HK
dc.subjectplacental site trophoblastic tumouren_HK
dc.titleGestational trophoblastic diseaseen_HK
dc.typeArticleen_HK
dc.identifier.emailChan, KKL:kklchan@hkucc.hku.hken_HK
dc.identifier.emailNgan, HYS:hysngan@hkucc.hku.hken_HK
dc.identifier.authorityChan, KKL=rp00499en_HK
dc.identifier.authorityNgan, HYS=rp00346en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1016/j.ogrm.2008.12.002en_HK
dc.identifier.scopuseid_2-s2.0-62149135327en_HK
dc.identifier.hkuros161187en_HK
dc.identifier.volume19en_HK
dc.identifier.issue4en_HK
dc.identifier.spage89en_HK
dc.identifier.epage97en_HK
dc.identifier.scopusauthoridTse, KY=8876026900en_HK
dc.identifier.scopusauthoridChan, KKL=8655666700en_HK
dc.identifier.scopusauthoridTam, KF=7201692816en_HK
dc.identifier.scopusauthoridNgan, HYS=34571944100en_HK

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats