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Article: The role of regular physical examination in the detection of ovarian cancer recurrence

TitleThe role of regular physical examination in the detection of ovarian cancer recurrence
Authors
KeywordsCa 125
Follow-up
Ovarian cancer recurrence
Ovarian carcinoma
Physical examination
Issue Date2008
PublisherAcademic Press. The Journal's web site is located at http://www.elsevier.com/locate/ygyno
Citation
Gynecologic Oncology, 2008, v. 110 n. 2, p. 158-161 How to Cite?
AbstractObjective: To evaluate how ovarian recurrences were first detected and the relative role of Ca 125, symptom enquiry and physical examination in recurrence detection. Methods: In this retrospective study, records from women with ovarian cancer recurrences diagnosed between 1999 and 2004 were reviewed to determine how the recurrences were first detected. Women were routinely followed up by a combination of symptom enquiry, physical examination and Ca 125. When recurrence was suspected, further investigations such as imaging and biopsy of the suspected recurrence would be arranged to confirm the diagnosis. The patients were followed up for a median of 53.5 months. Results: Eighty patients were identified to have ovarian cancer recurrences, with median time to recurrence of 12 months. Although 41 (51%) had abnormal physical findings, only three (3.8%) first presented with physical findings and none had positive physical findings alone. Ca 125 taken at the clinic visits in these 3 patients when the signs were detected turned out to be raised. For the remaining 77 patients, 49 (61%) and 28 (35%) first presented with raised Ca 125 level and symptoms respectively. The median survival from the time of recurrence for those first presented with Ca 125, symptoms and physical findings were 25 months, 17 months and 11 months respectively. Conclusion: Routine physical examination had a very limited additional role and could be possibly omitted as part of the routine follow up strategy. © 2008 Elsevier Inc. All rights reserved.
Persistent Identifierhttp://hdl.handle.net/10722/60342
ISSN
2015 Impact Factor: 4.198
2015 SCImago Journal Rankings: 2.284
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorChan, KKLen_HK
dc.contributor.authorTam, KFen_HK
dc.contributor.authorTse, KYen_HK
dc.contributor.authorNgan, HYSen_HK
dc.date.accessioned2010-05-31T04:08:43Z-
dc.date.available2010-05-31T04:08:43Z-
dc.date.issued2008en_HK
dc.identifier.citationGynecologic Oncology, 2008, v. 110 n. 2, p. 158-161en_HK
dc.identifier.issn0090-8258en_HK
dc.identifier.urihttp://hdl.handle.net/10722/60342-
dc.description.abstractObjective: To evaluate how ovarian recurrences were first detected and the relative role of Ca 125, symptom enquiry and physical examination in recurrence detection. Methods: In this retrospective study, records from women with ovarian cancer recurrences diagnosed between 1999 and 2004 were reviewed to determine how the recurrences were first detected. Women were routinely followed up by a combination of symptom enquiry, physical examination and Ca 125. When recurrence was suspected, further investigations such as imaging and biopsy of the suspected recurrence would be arranged to confirm the diagnosis. The patients were followed up for a median of 53.5 months. Results: Eighty patients were identified to have ovarian cancer recurrences, with median time to recurrence of 12 months. Although 41 (51%) had abnormal physical findings, only three (3.8%) first presented with physical findings and none had positive physical findings alone. Ca 125 taken at the clinic visits in these 3 patients when the signs were detected turned out to be raised. For the remaining 77 patients, 49 (61%) and 28 (35%) first presented with raised Ca 125 level and symptoms respectively. The median survival from the time of recurrence for those first presented with Ca 125, symptoms and physical findings were 25 months, 17 months and 11 months respectively. Conclusion: Routine physical examination had a very limited additional role and could be possibly omitted as part of the routine follow up strategy. © 2008 Elsevier Inc. All rights reserved.en_HK
dc.languageengen_HK
dc.publisherAcademic Press. The Journal's web site is located at http://www.elsevier.com/locate/ygynoen_HK
dc.relation.ispartofGynecologic Oncologyen_HK
dc.subjectCa 125en_HK
dc.subjectFollow-upen_HK
dc.subjectOvarian cancer recurrenceen_HK
dc.subjectOvarian carcinomaen_HK
dc.subjectPhysical examinationen_HK
dc.titleThe role of regular physical examination in the detection of ovarian cancer recurrenceen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0090-8258&volume=110&issue=2&spage=158&epage=161&date=2008&atitle=The+Role+Of+Regular+Physical+Examination+In+The+Detection+Of+Ovarian+Cancer+Recurrenceen_HK
dc.identifier.emailChan, KKL:kklchan@hkucc.hku.hken_HK
dc.identifier.emailNgan, HYS:hysngan@hkucc.hku.hken_HK
dc.identifier.authorityChan, KKL=rp00499en_HK
dc.identifier.authorityNgan, HYS=rp00346en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1016/j.ygyno.2008.04.030en_HK
dc.identifier.pmid18544459-
dc.identifier.scopuseid_2-s2.0-47349134005en_HK
dc.identifier.hkuros148410en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-47349134005&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume110en_HK
dc.identifier.issue2en_HK
dc.identifier.spage158en_HK
dc.identifier.epage161en_HK
dc.identifier.eissn1095-6859-
dc.identifier.isiWOS:000258205700007-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridChan, KKL=8655666700en_HK
dc.identifier.scopusauthoridTam, KF=7201692816en_HK
dc.identifier.scopusauthoridTse, KY=8876026900en_HK
dc.identifier.scopusauthoridNgan, HYS=34571944100en_HK

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