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Article: Quality of life in patients with laryngopharyngeal reflux

TitleQuality of life in patients with laryngopharyngeal reflux
Authors
KeywordsAnxiety
Depression
Gastroesophageal reflux disease
Laryngopharyngeal reflux
Quality of life
Issue Date2009
PublisherS Karger AG. The Journal's web site is located at http://www.karger.com/DIG
Citation
Digestion, 2009, v. 79 n. 1, p. 52-57 How to Cite?
AbstractBackground: Laryngopharyngeal reflux (LPR) disease is an extraesophageal manifestation of gastroesophageal reflux disease (GERD). The impact of GERD-related LPR on the psychological well-being and quality of life (QOL) in Chinese is not known. Aim: To assess the QOL in patients with LPR disease. Methods: 76 LPR and 73 healthy subjects were recruited. Psychological well-being was assessed by the Hospital Anxiety and Depression Score and QOL was assessed by SF-36. Results: 51/76 (67.1%) patients had GERD-related LPR. More LPR subjects had taken sick leave (36.2 vs. 5.6%, p = 0.001) and reported adverse social life impact (60.5 vs. 38.9%, p = 0.013). LPR patients showed significantly worse results on the Voice Handicap Index (47.8 vs. 7.6, p = 0.001), were more anxious and had worse QOL in social functioning, pain and general health perception domains of SF-36. GERD-related LPR subjects had a higher depression score (4.8 vs. 3.8, p = 0.014) and a lower mental summary score (41.8 vs. 48.4, p = 0.01) in SF-36 compared with those without GERD. Conclusions: LPR had a negative impact on psychological status, social functioning and QOL. GERD symptoms appeared to be the main contributor to decrease QOL. GERD-related LPR patients had a significant impact on the mental component of their QOL. © 2009 S. Karger AG, Basel.
Persistent Identifierhttp://hdl.handle.net/10722/59368
ISSN
2014 Impact Factor: 2.097
2014 SCImago Journal Rankings: 0.800
ISI Accession Number ID
Funding AgencyGrant Number
Shun Tak District Min Yuen Tong Gastroenterology Research Fund
Funding Information:

This project is sponsored by Shun Tak District Min Yuen Tong Gastroenterology Research Fund.

References

 

DC FieldValueLanguage
dc.contributor.authorCheung, TKen_HK
dc.contributor.authorLam, PKYen_HK
dc.contributor.authorWei, WIen_HK
dc.contributor.authorWong, WMen_HK
dc.contributor.authorNg, MLen_HK
dc.contributor.authorGu, Qen_HK
dc.contributor.authorHung, IFen_HK
dc.contributor.authorWong, BCYen_HK
dc.date.accessioned2010-05-31T03:48:34Z-
dc.date.available2010-05-31T03:48:34Z-
dc.date.issued2009en_HK
dc.identifier.citationDigestion, 2009, v. 79 n. 1, p. 52-57en_HK
dc.identifier.issn0012-2823en_HK
dc.identifier.urihttp://hdl.handle.net/10722/59368-
dc.description.abstractBackground: Laryngopharyngeal reflux (LPR) disease is an extraesophageal manifestation of gastroesophageal reflux disease (GERD). The impact of GERD-related LPR on the psychological well-being and quality of life (QOL) in Chinese is not known. Aim: To assess the QOL in patients with LPR disease. Methods: 76 LPR and 73 healthy subjects were recruited. Psychological well-being was assessed by the Hospital Anxiety and Depression Score and QOL was assessed by SF-36. Results: 51/76 (67.1%) patients had GERD-related LPR. More LPR subjects had taken sick leave (36.2 vs. 5.6%, p = 0.001) and reported adverse social life impact (60.5 vs. 38.9%, p = 0.013). LPR patients showed significantly worse results on the Voice Handicap Index (47.8 vs. 7.6, p = 0.001), were more anxious and had worse QOL in social functioning, pain and general health perception domains of SF-36. GERD-related LPR subjects had a higher depression score (4.8 vs. 3.8, p = 0.014) and a lower mental summary score (41.8 vs. 48.4, p = 0.01) in SF-36 compared with those without GERD. Conclusions: LPR had a negative impact on psychological status, social functioning and QOL. GERD symptoms appeared to be the main contributor to decrease QOL. GERD-related LPR patients had a significant impact on the mental component of their QOL. © 2009 S. Karger AG, Basel.en_HK
dc.languageengen_HK
dc.publisherS Karger AG. The Journal's web site is located at http://www.karger.com/DIGen_HK
dc.relation.ispartofDigestionen_HK
dc.rightsDigestion. Copyright © S Karger AG.en_HK
dc.subjectAnxietyen_HK
dc.subjectDepressionen_HK
dc.subjectGastroesophageal reflux diseaseen_HK
dc.subjectLaryngopharyngeal refluxen_HK
dc.subjectQuality of lifeen_HK
dc.subject.meshAdulten_HK
dc.subject.meshCase-Control Studiesen_HK
dc.subject.meshChi-Square Distributionen_HK
dc.subject.meshChinaen_HK
dc.subject.meshFemaleen_HK
dc.subject.meshGastroesophageal Reflux - psychologyen_HK
dc.subject.meshHumansen_HK
dc.subject.meshLaryngeal Diseases - psychologyen_HK
dc.subject.meshLaryngoscopyen_HK
dc.subject.meshLogistic Modelsen_HK
dc.subject.meshMaleen_HK
dc.subject.meshMiddle Ageden_HK
dc.subject.meshPharyngeal Diseases - psychologyen_HK
dc.subject.meshPsychiatric Status Rating Scalesen_HK
dc.subject.meshQuality of Lifeen_HK
dc.subject.meshQuestionnairesen_HK
dc.subject.meshRisk Factorsen_HK
dc.titleQuality of life in patients with laryngopharyngeal refluxen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0012-2823&volume=79&spage=52&epage=57&date=2009&atitle=Quality+of+life+in+patients+with+laryngopharyngeal+refluxen_HK
dc.identifier.emailWei, WI: hrmswwi@hku.hken_HK
dc.identifier.emailNg, ML: manwa@hku.hken_HK
dc.identifier.emailHung, IF: ivanhung@hkucc.hku.hken_HK
dc.identifier.emailWong, BCY: bcywong@hku.hken_HK
dc.identifier.authorityWei, WI=rp00323en_HK
dc.identifier.authorityNg, ML=rp00942en_HK
dc.identifier.authorityHung, IF=rp00508en_HK
dc.identifier.authorityWong, BCY=rp00429en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1159/000205267en_HK
dc.identifier.pmid19252403en_HK
dc.identifier.scopuseid_2-s2.0-60949088870en_HK
dc.identifier.hkuros154936en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-60949088870&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume79en_HK
dc.identifier.issue1en_HK
dc.identifier.spage52en_HK
dc.identifier.epage57en_HK
dc.identifier.isiWOS:000264026200011-
dc.publisher.placeSwitzerlanden_HK
dc.identifier.scopusauthoridCheung, TK=7103334158en_HK
dc.identifier.scopusauthoridLam, PKY=7202366058en_HK
dc.identifier.scopusauthoridWei, WI=7403321552en_HK
dc.identifier.scopusauthoridWong, WM=7403972413en_HK
dc.identifier.scopusauthoridNg, ML=15923631600en_HK
dc.identifier.scopusauthoridGu, Q=24469982400en_HK
dc.identifier.scopusauthoridHung, IF=7006103457en_HK
dc.identifier.scopusauthoridWong, BCY=7402023340en_HK

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