Granted Patent: Rapid Genetic Screening Method
| Title | Rapid Genetic Screening Method |
|---|---|
| Granted Patent | US 6020126 |
| Granted Date | 2000-02-01 |
| Priority Date | 1997-03-21 US 08/821524 1996-03-21 US 08/013913P |
| Inventors | Norden, B Zielenski, J Tsui, L-C Nielsen, P Jonsson, M Dulay, MT Carlsson, C Zare, RN |
| Citation | US Patent 6020126. Washington, DC: US Patent and Trademark Office (USPTO), 2000 [How to Cite?] |
| Abstract | A Rapid And Sensitive Detection Method Capable Of Reliably Distinguishing Fragments Identical To A Defined Sequence From Fragments Containing A Single Base Pair Mismatch Relative To The Defined Sequence. The Method Employs A Peptide Analog Antisense Probe, Such As A Peptide Nucleic Acid (Pna) Probe, Which Hybridizes With Dna To Forms Complexes Having Higher Thermal Stability, But Greater Sensitivity To Base Pair Mismatches, Than Corresponding Dna/Dna Complexes. The Method May Be Used In A Number Of Applications, Including Genetic Screening And Hybridization Sequencing Applications. |
| References | US 5593559 (A) 1997-01-14 WO 9220703 (A1) 1992-11-26 |
| dc.contributor.inventor | Norden, B |
|---|---|
| dc.contributor.inventor | Zielenski, J |
| dc.contributor.inventor | Tsui, L-C |
| dc.contributor.inventor | Nielsen, P |
| dc.contributor.inventor | Jonsson, M |
| dc.contributor.inventor | Dulay, MT |
| dc.contributor.inventor | Carlsson, C |
| dc.contributor.inventor | Zare, RN |
| dc.date.accessioned | 2007-03-23T04:52:18Z |
| patents.date.application | 1997-03-21 |
| dc.date.available | 2007-03-23T04:52:18Z |
| patents.date.granted | 2000-02-01 |
| patents.date.priority | 1997-03-21 US 08/821524 |
| patents.date.priority | 1996-03-21 US 08/013913P |
| dc.description.abstract | A Rapid And Sensitive Detection Method Capable Of Reliably Distinguishing Fragments Identical To A Defined Sequence From Fragments Containing A Single Base Pair Mismatch Relative To The Defined Sequence. The Method Employs A Peptide Analog Antisense Probe, Such As A Peptide Nucleic Acid (Pna) Probe, Which Hybridizes With Dna To Forms Complexes Having Higher Thermal Stability, But Greater Sensitivity To Base Pair Mismatches, Than Corresponding Dna/Dna Complexes. The Method May Be Used In A Number Of Applications, Including Genetic Screening And Hybridization Sequencing Applications. |
| patents.description.assignee | Hsc Reasearch And Dev Limited [Ca]; Trustees Of The Leland Stamfor [Us] |
| patents.description.cc | US |
| patents.description.country | United States of America |
| patents.description.kind | A |
| dc.description.nature | published_or_final_version |
| dc.format.extent | 1647855 bytes |
| dc.format.extent | 30208 bytes |
| dc.format.mimetype | application/pdf |
| dc.format.mimetype | application/msword |
| patents.identifier.application | US 08/821524 |
| dc.identifier.citation | US Patent 6020126. Washington, DC: US Patent and Trademark Office (USPTO), 2000 [How to Cite?] |
| patents.identifier.granted | US 6020126 |
| dc.identifier.uri | http://hdl.handle.net/10722/43684 |
| dc.language | eng |
| patents.relation.family | US 6020126 (A) 2000-02-01 |
| dc.relation.isreferencedby | US 2008293107 (A1) 2008-11-27 |
| dc.relation.isreferencedby | US 7659072 (B2) 2010-02-09 |
| dc.relation.isreferencedby | US 2009286690 (A1) 2009-11-19 |
| dc.relation.isreferencedby | US 7794943 (B2) 2010-09-14 |
| dc.relation.isreferencedby | US 2007156037 (A1) 2007-07-05 |
| dc.relation.isreferencedby | US 7904140 (B2) 2011-03-08 |
| dc.relation.isreferencedby | US 2004009612 (A1) 2004-01-15 |
| dc.relation.isreferencedby | US 7371520 (B2) 2008-05-13 |
| dc.relation.isreferencedby | EP 1436424 (A2) 2004-07-14 |
| dc.relation.isreferencedby | EP 1436424 (A4) 2005-11-16 |
| dc.relation.isreferencedby | US 7058517 (B1) 2006-06-06 |
| dc.relation.isreferencedby | US 2003059789 (A1) 2003-03-27 |
| dc.relation.isreferencedby | US 6962906 (B2) 2005-11-08 |
| dc.relation.isreferencedby | US 6931326 (B1) 2005-08-16 |
| dc.relation.isreferencedby | US 2002155989 (A1) 2002-10-24 |
| dc.relation.isreferencedby | US 7115738 (B2) 2006-10-03 |
| dc.relation.isreferencedby | US 6441152 (B1) 2002-08-27 |
| dc.relation.isreferencedby | US 6361942 (B1) 2002-03-26 |
| dc.relation.isreferencedby | US 6979536 (B1) 2005-12-27 |
| dc.relation.references | US 5593559 (A) 1997-01-14 |
| dc.relation.references | WO 9220703 (A1) 1992-11-26 |
| dc.rights | Creative Commons: Attribution 3.0 Hong Kong License For Public Patent Documents |
| dc.title | Rapid Genetic Screening Method |
| dc.type | Patent |
| patents.type | Patent_granted |