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Article: Presence of Epstein-Barr virus in lymphoepithelioma-like carcinoma of the middle ear

TitlePresence of Epstein-Barr virus in lymphoepithelioma-like carcinoma of the middle ear
Authors
KeywordsEar
Epstein-Barr virus
Lymphoepithelioma
Issue Date1998
PublisherB M J Publishing Group. The Journal's web site is located at http://jcp.bmjjournals.com/
Citation
Journal Of Clinical Pathology, 1998, v. 51 n. 8, p. 602-605 How to Cite?
AbstractAim - To examine the association of Epstein-Bart virus (EBV) with carcinoma of the ear. Methods - Five non-keratinising squamous cell carcinomas and two undifferentiated carcinomas of the ear were examined. In situ hybridisation was used to localised EBV-encoded RNAs (EBER). Immunohistochemical methods to detect LMP-1 and EBNA2 were performed in the EBER positive cases. Results - Two cases were EBER positive, including one non-keratinising and one undifferentiated carcinoma. Both showed identical morphology to those arising from the nasopharynx, with abundant lymphoid stroma. They were both negative for LMP-1 and EBNA2. Conclusions - EBV associated carcinoma with the morphology of lymphoepithelioma can also arise from the middle ear.
Persistent Identifierhttp://hdl.handle.net/10722/43605
ISSN
2015 Impact Factor: 2.912
2015 SCImago Journal Rankings: 1.260
PubMed Central ID
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorLeung, SYen_HK
dc.contributor.authorYuen, STen_HK
dc.contributor.authorHo, CMen_HK
dc.contributor.authorKwong, WKen_HK
dc.contributor.authorChung, LPen_HK
dc.date.accessioned2007-03-23T04:50:09Z-
dc.date.available2007-03-23T04:50:09Z-
dc.date.issued1998en_HK
dc.identifier.citationJournal Of Clinical Pathology, 1998, v. 51 n. 8, p. 602-605en_HK
dc.identifier.issn0021-9746en_HK
dc.identifier.urihttp://hdl.handle.net/10722/43605-
dc.description.abstractAim - To examine the association of Epstein-Bart virus (EBV) with carcinoma of the ear. Methods - Five non-keratinising squamous cell carcinomas and two undifferentiated carcinomas of the ear were examined. In situ hybridisation was used to localised EBV-encoded RNAs (EBER). Immunohistochemical methods to detect LMP-1 and EBNA2 were performed in the EBER positive cases. Results - Two cases were EBER positive, including one non-keratinising and one undifferentiated carcinoma. Both showed identical morphology to those arising from the nasopharynx, with abundant lymphoid stroma. They were both negative for LMP-1 and EBNA2. Conclusions - EBV associated carcinoma with the morphology of lymphoepithelioma can also arise from the middle ear.en_HK
dc.format.extent259202 bytes-
dc.format.extent25600 bytes-
dc.format.mimetypeapplication/pdf-
dc.format.mimetypeapplication/msword-
dc.languageengen_HK
dc.publisherB M J Publishing Group. The Journal's web site is located at http://jcp.bmjjournals.com/en_HK
dc.relation.ispartofJournal of Clinical Pathologyen_HK
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License-
dc.rightsJournal of Clinical Pathology. Copyright © B M J Publishing Group.en_HK
dc.subjectEaren_HK
dc.subjectEpstein-Barr virusen_HK
dc.subjectLymphoepitheliomaen_HK
dc.subject.meshCarcinoma, squamous cell - pathology - radiography - virologyen_HK
dc.subject.meshEar, middleen_HK
dc.subject.meshEpstein-barr virus infections - complicationsen_HK
dc.subject.meshHerpesvirus 4, human - isolation & purificationen_HK
dc.subject.meshIn situ hybridizationen_HK
dc.titlePresence of Epstein-Barr virus in lymphoepithelioma-like carcinoma of the middle earen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0021-9746&volume=51&issue=8&spage=602&epage=605&date=1999&atitle=Presence+of+Epstein-Barr+virus+in+lymphoepithelioma-like+carcinoma+of+the+middle+earen_HK
dc.identifier.emailLeung, SY: suetyi@hku.hken_HK
dc.identifier.emailChung, LP: lpchung@hkucc.hku.hken_HK
dc.identifier.authorityLeung, SY=rp00359en_HK
dc.identifier.authorityChung, LP=rp00249en_HK
dc.description.naturepublished_or_final_versionen_HK
dc.identifier.pmid9828819-
dc.identifier.pmcidPMC500853-
dc.identifier.scopuseid_2-s2.0-0031872919en_HK
dc.identifier.hkuros40701-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0031872919&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume51en_HK
dc.identifier.issue8en_HK
dc.identifier.spage602en_HK
dc.identifier.epage605en_HK
dc.identifier.isiWOS:000075409200009-
dc.publisher.placeUnited Kingdomen_HK
dc.identifier.scopusauthoridLeung, SY=7202044886en_HK
dc.identifier.scopusauthoridYuen, ST=7103160927en_HK
dc.identifier.scopusauthoridHo, CM=7404652540en_HK
dc.identifier.scopusauthoridKwong, WK=7005955797en_HK
dc.identifier.scopusauthoridChung, LP=24315879100en_HK

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