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Article: Serial assessment of left ventricular diastolic function after Fontan procedure

TitleSerial assessment of left ventricular diastolic function after Fontan procedure
Authors
KeywordsDiastolic function
Fontan procedure
Issue Date2000
PublisherB M J Publishing Group. The Journal's web site is located at http://heart.bmjjournals.com/
Citation
Heart, 2000, v. 83 n. 4, p. 420-424 How to Cite?
AbstractObjective - To assess longitudinal changes in systemic ventricular diastolic function late after the Fontan procedure. Design and patients - Prospective study of 13 patients at 2.8 (2.0) years (early) and again at 11.4 (2.0) years (late) after the Fontan procedure by Doppler echocardiography with simultaneous ECG, phonocardiogram, and respirometer. Setting - Tertiary paediatric cardiac centre. Results - The isovolumic relaxation time (IVRT) was significantly longer, and E wave deceleration time, E and A wave velocities, and E:A velocity ratio were reduced compared to normal both early and late after the procedure. The mean (SD) z score of IVRT decreased significantly from +2.50 (1.00) to +1.24 (0.80) (p = 0.002), and the z score of the E wave deceleration time decreased from -1.69 (1.31) to -2.40 (1.47) (p = 0.03) during follow up. The A wave deceleration time also tended to decrease (early 80 (12) ms v late 73 (11) ms, p = 0.13) with increased follow up. There were no changes of the E and A wave velocities and E:A velocity ratio. The E wave velocity was inversely related to IVRT both early (r = - 0.82, p = 0.001) and late (r = -0.59, p = 0.034) after the operation. The prevalence of diastolic flow during isovolumic relaxation decreased from 85% (11/13) to 38% (5/13) (p = 0.04), while that of mid diastolic flow increased from 23% (3/13) to 77% (10/13) (p = 0.02) between the two assessments. Conclusions - Left ventricular diastolic function remains highly abnormal late after the Fontan procedure. The longitudinal changes demonstrated on follow up are compatible with reduction of left ventricular compliance in addition to persisting abnormalities of relaxation.
Persistent Identifierhttp://hdl.handle.net/10722/43144
ISSN
2015 Impact Factor: 5.693
2015 SCImago Journal Rankings: 2.647
PubMed Central ID
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorCheung, YFen_HK
dc.contributor.authorPenny, DJen_HK
dc.contributor.authorRedington, ANen_HK
dc.date.accessioned2007-03-23T04:39:55Z-
dc.date.available2007-03-23T04:39:55Z-
dc.date.issued2000en_HK
dc.identifier.citationHeart, 2000, v. 83 n. 4, p. 420-424en_HK
dc.identifier.issn1355-6037en_HK
dc.identifier.urihttp://hdl.handle.net/10722/43144-
dc.description.abstractObjective - To assess longitudinal changes in systemic ventricular diastolic function late after the Fontan procedure. Design and patients - Prospective study of 13 patients at 2.8 (2.0) years (early) and again at 11.4 (2.0) years (late) after the Fontan procedure by Doppler echocardiography with simultaneous ECG, phonocardiogram, and respirometer. Setting - Tertiary paediatric cardiac centre. Results - The isovolumic relaxation time (IVRT) was significantly longer, and E wave deceleration time, E and A wave velocities, and E:A velocity ratio were reduced compared to normal both early and late after the procedure. The mean (SD) z score of IVRT decreased significantly from +2.50 (1.00) to +1.24 (0.80) (p = 0.002), and the z score of the E wave deceleration time decreased from -1.69 (1.31) to -2.40 (1.47) (p = 0.03) during follow up. The A wave deceleration time also tended to decrease (early 80 (12) ms v late 73 (11) ms, p = 0.13) with increased follow up. There were no changes of the E and A wave velocities and E:A velocity ratio. The E wave velocity was inversely related to IVRT both early (r = - 0.82, p = 0.001) and late (r = -0.59, p = 0.034) after the operation. The prevalence of diastolic flow during isovolumic relaxation decreased from 85% (11/13) to 38% (5/13) (p = 0.04), while that of mid diastolic flow increased from 23% (3/13) to 77% (10/13) (p = 0.02) between the two assessments. Conclusions - Left ventricular diastolic function remains highly abnormal late after the Fontan procedure. The longitudinal changes demonstrated on follow up are compatible with reduction of left ventricular compliance in addition to persisting abnormalities of relaxation.en_HK
dc.format.extent192586 bytes-
dc.format.extent25600 bytes-
dc.format.mimetypeapplication/pdf-
dc.format.mimetypeapplication/msword-
dc.languageengen_HK
dc.publisherB M J Publishing Group. The Journal's web site is located at http://heart.bmjjournals.com/en_HK
dc.relation.ispartofHearten_HK
dc.rightsHeart. Copyright © B M J Publishing Group.en_HK
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License-
dc.subjectDiastolic functionen_HK
dc.subjectFontan procedureen_HK
dc.subject.meshDiastolic functionen_HK
dc.subject.meshFontan procedureen_HK
dc.subject.meshVentricular function, leften_HK
dc.subject.meshEchocardiography, doppleren_HK
dc.subject.meshElectrocardiographyen_HK
dc.titleSerial assessment of left ventricular diastolic function after Fontan procedureen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1355-6037&volume=83&issue=4&spage=420&epage=424&date=2000&atitle=Serial+assessment+of+left+ventricular+diastolic+function+after+Fontan+procedureen_HK
dc.identifier.emailCheung, YF:xfcheung@hku.hken_HK
dc.identifier.authorityCheung, YF=rp00382en_HK
dc.description.naturepublished_or_final_versionen_HK
dc.identifier.doi10.1136/heart.83.4.420en_HK
dc.identifier.pmid10722541-
dc.identifier.pmcidPMC1729362-
dc.identifier.scopuseid_2-s2.0-0034122961en_HK
dc.identifier.hkuros48342-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0034122961&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume83en_HK
dc.identifier.issue4en_HK
dc.identifier.spage420en_HK
dc.identifier.epage424en_HK
dc.identifier.isiWOS:000086141900013-
dc.publisher.placeUnited Kingdomen_HK
dc.identifier.scopusauthoridCheung, YF=7202111067en_HK
dc.identifier.scopusauthoridPenny, DJ=7101751367en_HK
dc.identifier.scopusauthoridRedington, AN=7102622991en_HK
dc.identifier.citeulike3417385-

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