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Book Chapter: Adefovir dipivoxil

TitleAdefovir dipivoxil
Authors
Issue Date2018
PublisherCRC Press
Citation
Adefovir dipivoxil. In Grayson, ML (Editor-in-chief), Kucers' The Use of Antibiotics: A Clinical Review of Antibacterial, Antifungal, Antiparasitic, and Antiviral Drugs (7th ed.), v. 3, p. 4335-4344. Boca Raton, FL: CRC Press, 2018 How to Cite?
AbstractAdefovir dipivoxil, 9-[2[[bis[(pivaloyloxy)-methoxy]phosphinyl]- methoxy]ethyl] adenine, also known as bis(POM)- PMEA, and PMEA-9-2-phosphonylmethoxyethyl-adenine, is the oral diester prodrug of adefovir, an acyclic nucleotide analog of deoxyadenosine monophosphate (Dando and Plosker, 2003). Adefovir dipivoxil is rapidly converted to adefovir in the gastrointestinal tract and then further sequentially phosphorylated intracellularly by cellular kinases to its active metabolite, adefovir diphosphate. © 2018 by Taylor & Francis Group, LLC.
DescriptionSection 5 - part 5.3 - chapter 255
Persistent Identifierhttp://hdl.handle.net/10722/246905
ISBN

 

DC FieldValueLanguage
dc.contributor.authorSeto, WKW-
dc.contributor.authorLai, CL-
dc.contributor.authorYuen, RMF-
dc.date.accessioned2017-10-18T08:19:11Z-
dc.date.available2017-10-18T08:19:11Z-
dc.date.issued2018-
dc.identifier.citationAdefovir dipivoxil. In Grayson, ML (Editor-in-chief), Kucers' The Use of Antibiotics: A Clinical Review of Antibacterial, Antifungal, Antiparasitic, and Antiviral Drugs (7th ed.), v. 3, p. 4335-4344. Boca Raton, FL: CRC Press, 2018-
dc.identifier.isbn9781498747950-
dc.identifier.urihttp://hdl.handle.net/10722/246905-
dc.descriptionSection 5 - part 5.3 - chapter 255-
dc.description.abstractAdefovir dipivoxil, 9-[2[[bis[(pivaloyloxy)-methoxy]phosphinyl]- methoxy]ethyl] adenine, also known as bis(POM)- PMEA, and PMEA-9-2-phosphonylmethoxyethyl-adenine, is the oral diester prodrug of adefovir, an acyclic nucleotide analog of deoxyadenosine monophosphate (Dando and Plosker, 2003). Adefovir dipivoxil is rapidly converted to adefovir in the gastrointestinal tract and then further sequentially phosphorylated intracellularly by cellular kinases to its active metabolite, adefovir diphosphate. © 2018 by Taylor & Francis Group, LLC.-
dc.languageeng-
dc.publisherCRC Press-
dc.relation.ispartofKucers' The Use of Antibiotics: A Clinical Review of Antibacterial, Antifungal, Antiparasitic, and Antiviral Drugs (7th ed.)-
dc.titleAdefovir dipivoxil-
dc.typeBook_Chapter-
dc.identifier.emailSeto, WKW: wkseto@hku.hk-
dc.identifier.emailLai, CL: hrmelcl@hkucc.hku.hk-
dc.identifier.emailYuen, RMF: mfyuen@hku.hk-
dc.identifier.authoritySeto, WKW=rp01659-
dc.identifier.authorityLai, CL=rp00314-
dc.identifier.authorityYuen, RMF=rp00479-
dc.identifier.doi10.1201/9781315152110-
dc.identifier.scopuseid_2-s2.0-85056686855-
dc.identifier.hkuros280081-
dc.identifier.volume3-
dc.identifier.spage4335-
dc.identifier.epage4344-
dc.publisher.placeBoca Raton, FL-

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