File Download
There are no files associated with this item.
Links for fulltext
(May Require Subscription)
- Publisher Website: 10.1159/000430461
- Scopus: eid_2-s2.0-84930246214
- PMID: 26021692
- WOS: WOS:000355316900015
- Find via
Supplementary
- Citations:
- Appears in Collections:
Article: Diffusion-perfusion mismatch in single subcortical infarction: A predictor of early neurological deterioration and poor functional outcome
Title | Diffusion-perfusion mismatch in single subcortical infarction: A predictor of early neurological deterioration and poor functional outcome |
---|---|
Authors | |
Keywords | Prognosis Single subcortical infarction Diffusion-perfusion mismatch Neurological deterioration |
Issue Date | 2015 |
Citation | European Neurology, 2015, v. 73, n. 5-6, p. 353-359 How to Cite? |
Abstract | © 2015 S. Karger AG, Basel.Background/Aims: Early neurological deterioration (END) is frequently observed and related to poor functional outcome in patients with single subcortical infarction (SSI). We evaluated the role of diffusion-perfusion mismatch (DPM) as a predictor of END and functional outcome in patients with SSI. Methods: We retrospectively analyzed data for 274 patients with acute SSI. DPM was positive in the presence of a lesion on the perfusion map that was larger than that on the corresponding slice on diffusion-weighted imaging. END was defined as an increase of <1 points in the motor portion of the National Institute of Health Stroke Scale (NIHSS) within 72 h from MRI acquisition. Patients with a modified Rankin Scale (mRS) score of 3 or more at day 30 were considered having a poor functional outcome. Results: DPM was more frequently observed in the END (+) than in the END (-) group (21/35 (60.0%) vs. 50/239 (20.9%); p < 0.001). After adjusting for covariates, the presence of DPM and NIHSS score on admission were independently associated with END (DPM, OR 5.03, p < 0.001; NIHSS, OR 1.14, p = 0.033) and poor functional outcome (DPM, OR 2.44, p = 0.018; NIHSS, OR 1.48, p < 0.001). Conclusions: The DPM concept is applicable to prediction of END and functional disability in patients with SSI. |
Persistent Identifier | http://hdl.handle.net/10722/238135 |
ISSN | 2023 Impact Factor: 2.1 2023 SCImago Journal Rankings: 0.573 |
ISI Accession Number ID |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, Jun Pyo | - |
dc.contributor.author | Kim, Suk Jae | - |
dc.contributor.author | Lee, Jung Jae | - |
dc.contributor.author | Cha, Ji Hoon | - |
dc.contributor.author | Bang, Oh Young | - |
dc.contributor.author | Chung, Chin Sang | - |
dc.contributor.author | Lee, Kwang Ho | - |
dc.contributor.author | Kim, Gyeong Moon | - |
dc.date.accessioned | 2017-02-03T02:13:09Z | - |
dc.date.available | 2017-02-03T02:13:09Z | - |
dc.date.issued | 2015 | - |
dc.identifier.citation | European Neurology, 2015, v. 73, n. 5-6, p. 353-359 | - |
dc.identifier.issn | 0014-3022 | - |
dc.identifier.uri | http://hdl.handle.net/10722/238135 | - |
dc.description.abstract | © 2015 S. Karger AG, Basel.Background/Aims: Early neurological deterioration (END) is frequently observed and related to poor functional outcome in patients with single subcortical infarction (SSI). We evaluated the role of diffusion-perfusion mismatch (DPM) as a predictor of END and functional outcome in patients with SSI. Methods: We retrospectively analyzed data for 274 patients with acute SSI. DPM was positive in the presence of a lesion on the perfusion map that was larger than that on the corresponding slice on diffusion-weighted imaging. END was defined as an increase of <1 points in the motor portion of the National Institute of Health Stroke Scale (NIHSS) within 72 h from MRI acquisition. Patients with a modified Rankin Scale (mRS) score of 3 or more at day 30 were considered having a poor functional outcome. Results: DPM was more frequently observed in the END (+) than in the END (-) group (21/35 (60.0%) vs. 50/239 (20.9%); p < 0.001). After adjusting for covariates, the presence of DPM and NIHSS score on admission were independently associated with END (DPM, OR 5.03, p < 0.001; NIHSS, OR 1.14, p = 0.033) and poor functional outcome (DPM, OR 2.44, p = 0.018; NIHSS, OR 1.48, p < 0.001). Conclusions: The DPM concept is applicable to prediction of END and functional disability in patients with SSI. | - |
dc.language | eng | - |
dc.relation.ispartof | European Neurology | - |
dc.subject | Prognosis | - |
dc.subject | Single subcortical infarction | - |
dc.subject | Diffusion-perfusion mismatch | - |
dc.subject | Neurological deterioration | - |
dc.title | Diffusion-perfusion mismatch in single subcortical infarction: A predictor of early neurological deterioration and poor functional outcome | - |
dc.type | Article | - |
dc.description.nature | link_to_subscribed_fulltext | - |
dc.identifier.doi | 10.1159/000430461 | - |
dc.identifier.pmid | 26021692 | - |
dc.identifier.scopus | eid_2-s2.0-84930246214 | - |
dc.identifier.volume | 73 | - |
dc.identifier.issue | 5-6 | - |
dc.identifier.spage | 353 | - |
dc.identifier.epage | 359 | - |
dc.identifier.eissn | 1421-9913 | - |
dc.identifier.isi | WOS:000355316900015 | - |
dc.identifier.issnl | 0014-3022 | - |