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Conference Paper: Prevalence, predictors and clinical outcome of residual pulmonary hypertension following tricuspid annuloplasty
Title | Prevalence, predictors and clinical outcome of residual pulmonary hypertension following tricuspid annuloplasty |
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Authors | |
Issue Date | 2016 |
Publisher | Oxford University Press. The Journal's web site is located at http://eurheartj.oxfordjournals.org/ |
Citation | The 2016 Annual Congress of the European Society of Cardiology (ESC), Rome Italy, 27-31 August 2016. In European Heart Journal, 2016, v. 37 n. Suppl. 1, p. 752, abstract no. P3704 How to Cite? |
Abstract | BACKGROUND: Tricuspid annuloplasty (TA) is increasingly performed during left heart valve surgery but the postoperative clinical outcome is poor. PURPOSE: The aim of this study was to determine whether residual pulmonary hypertension (PHT) contributes to the adverse outcome. METHODS: 137 patients (age, 61±11 years; men, 30%) who underwent TA during left-side valve surgery were enrolled. The mean pulmonary artery systolic pressure (PASP) before surgery was 49±13mmHg and 32±15mmHg following surgery. Patients were divided into three groups according to postoperative PASP: no residual PHT (n=78, 57%), mild residual PHT (n=43, 31%), or significant residual PHT (n=16, 12%). RESULTS: A preoperative larger RV geometry and TV tethering area were associated with mild or significant residual PHT. A total of 24 adverse events (20 heart failure and 4 cardiovascular death) occurred during a median follow-up of 25 months. Kaplan-Meier survival curve demonstrated that patients with significant residual PHT had the highest percentage of adverse events followed by those with mild residual PHT. Patients with no residual PHT had a very low risk of adverse events. Multivariable Cox regression analysis revealed that both mild (hazard ratio=4.94; 95% confidence interval=1.34–18.16; P=0.02) and significant residual PHT (hazard ratio=8.67; 95% confidence interval=2.43–30.98; P<0.01) were independent factors associated with adverse events. CONCLUSIONS: The present study demonstrated that 43% of patients who underwent TA had residual PHT. The presence of mild or significant residual PHT was associated with adverse events in these patients. |
Description | Poster Session 4 - Aortic valve disease: no. P3704 |
Persistent Identifier | http://hdl.handle.net/10722/232396 |
ISSN | 2023 Impact Factor: 37.6 2023 SCImago Journal Rankings: 4.091 |
DC Field | Value | Language |
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dc.contributor.author | Chen, Y | - |
dc.contributor.author | Liu, J | - |
dc.contributor.author | Chan, DTM | - |
dc.contributor.author | Wong, CK | - |
dc.contributor.author | Zhen, Z | - |
dc.contributor.author | Tse, HF | - |
dc.contributor.author | Yiu, KH | - |
dc.date.accessioned | 2016-09-20T05:29:41Z | - |
dc.date.available | 2016-09-20T05:29:41Z | - |
dc.date.issued | 2016 | - |
dc.identifier.citation | The 2016 Annual Congress of the European Society of Cardiology (ESC), Rome Italy, 27-31 August 2016. In European Heart Journal, 2016, v. 37 n. Suppl. 1, p. 752, abstract no. P3704 | - |
dc.identifier.issn | 0195-668X | - |
dc.identifier.uri | http://hdl.handle.net/10722/232396 | - |
dc.description | Poster Session 4 - Aortic valve disease: no. P3704 | - |
dc.description.abstract | BACKGROUND: Tricuspid annuloplasty (TA) is increasingly performed during left heart valve surgery but the postoperative clinical outcome is poor. PURPOSE: The aim of this study was to determine whether residual pulmonary hypertension (PHT) contributes to the adverse outcome. METHODS: 137 patients (age, 61±11 years; men, 30%) who underwent TA during left-side valve surgery were enrolled. The mean pulmonary artery systolic pressure (PASP) before surgery was 49±13mmHg and 32±15mmHg following surgery. Patients were divided into three groups according to postoperative PASP: no residual PHT (n=78, 57%), mild residual PHT (n=43, 31%), or significant residual PHT (n=16, 12%). RESULTS: A preoperative larger RV geometry and TV tethering area were associated with mild or significant residual PHT. A total of 24 adverse events (20 heart failure and 4 cardiovascular death) occurred during a median follow-up of 25 months. Kaplan-Meier survival curve demonstrated that patients with significant residual PHT had the highest percentage of adverse events followed by those with mild residual PHT. Patients with no residual PHT had a very low risk of adverse events. Multivariable Cox regression analysis revealed that both mild (hazard ratio=4.94; 95% confidence interval=1.34–18.16; P=0.02) and significant residual PHT (hazard ratio=8.67; 95% confidence interval=2.43–30.98; P<0.01) were independent factors associated with adverse events. CONCLUSIONS: The present study demonstrated that 43% of patients who underwent TA had residual PHT. The presence of mild or significant residual PHT was associated with adverse events in these patients. | - |
dc.language | eng | - |
dc.publisher | Oxford University Press. The Journal's web site is located at http://eurheartj.oxfordjournals.org/ | - |
dc.relation.ispartof | European Heart Journal | - |
dc.relation.ispartof | The 2016 Annual Congress of the European Society of Cardiology (ESC) | - |
dc.title | Prevalence, predictors and clinical outcome of residual pulmonary hypertension following tricuspid annuloplasty | - |
dc.type | Conference_Paper | - |
dc.identifier.email | Liu, J: liujuhua@hku.hk | - |
dc.identifier.email | Chan, DTM: dtmchan@hku.hk | - |
dc.identifier.email | Tse, HF: hftse@hkucc.hku.hk | - |
dc.identifier.email | Yiu, KH: khkyiu@hku.hk | - |
dc.identifier.authority | Chan, DTM=rp00394 | - |
dc.identifier.authority | Tse, HF=rp00428 | - |
dc.identifier.authority | Yiu, KH=rp01490 | - |
dc.identifier.hkuros | 263234 | - |
dc.identifier.hkuros | 311815 | - |
dc.identifier.volume | 37 | - |
dc.identifier.issue | Suppl. 1 | - |
dc.identifier.spage | 752 | - |
dc.identifier.epage | 752 | - |
dc.publisher.place | United Kingdom | - |
dc.identifier.partofdoi | 10.1093/eurheartj/ehw433 | - |
dc.identifier.issnl | 0195-668X | - |