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Conference Paper: Prevalence, predictors and clinical outcome of residual pulmonary hypertension following tricuspid annuloplasty

TitlePrevalence, predictors and clinical outcome of residual pulmonary hypertension following tricuspid annuloplasty
Authors
Issue Date2016
PublisherOxford University Press. The Journal's web site is located at http://eurheartj.oxfordjournals.org/
Citation
The 2016 Annual Congress of the European Society of Cardiology (ESC), Rome Italy, 27-31 August 2016. In European Heart Journal, 2016, v. 37 suppl. 1, p. 752 How to Cite?
AbstractBACKGROUND: Tricuspid annuloplasty (TA) is increasingly performed during left heart valve surgery but the postoperative clinical outcome is poor. PURPOSE: The aim of this study was to determine whether residual pulmonary hypertension (PHT) contributes to the adverse outcome. METHODS: 137 patients (age, 61±11 years; men, 30%) who underwent TA during left-side valve surgery were enrolled. The mean pulmonary artery systolic pressure (PASP) before surgery was 49±13mmHg and 32±15mmHg following surgery. Patients were divided into three groups according to postoperative PASP: no residual PHT (n=78, 57%), mild residual PHT (n=43, 31%), or significant residual PHT (n=16, 12%). RESULTS: A preoperative larger RV geometry and TV tethering area were associated with mild or significant residual PHT. A total of 24 adverse events (20 heart failure and 4 cardiovascular death) occurred during a median follow-up of 25 months. Kaplan-Meier survival curve demonstrated that patients with significant residual PHT had the highest percentage of adverse events followed by those with mild residual PHT. Patients with no residual PHT had a very low risk of adverse events. Multivariable Cox regression analysis revealed that both mild (hazard ratio=4.94; 95% confidence interval=1.34–18.16; P=0.02) and significant residual PHT (hazard ratio=8.67; 95% confidence interval=2.43–30.98; P<0.01) were independent factors associated with adverse events. CONCLUSIONS: The present study demonstrated that 43% of patients who underwent TA had residual PHT. The presence of mild or significant residual PHT was associated with adverse events in these patients.
DescriptionPoster Session 4 - Aortic valve disease: no. P3704
This journal suppl. entitled: ESC Congress 2016 27 - 31 August Rome, Italy
Persistent Identifierhttp://hdl.handle.net/10722/232396
ISSN
2015 Impact Factor: 15.064
2015 SCImago Journal Rankings: 6.997

 

DC FieldValueLanguage
dc.contributor.authorChen, Y-
dc.contributor.authorLiu, J-
dc.contributor.authorChan, D-
dc.contributor.authorWong, CK-
dc.contributor.authorZhen, Z-
dc.contributor.authorTse, HF-
dc.contributor.authorYiu, KH-
dc.date.accessioned2016-09-20T05:29:41Z-
dc.date.available2016-09-20T05:29:41Z-
dc.date.issued2016-
dc.identifier.citationThe 2016 Annual Congress of the European Society of Cardiology (ESC), Rome Italy, 27-31 August 2016. In European Heart Journal, 2016, v. 37 suppl. 1, p. 752-
dc.identifier.issn0195-668X-
dc.identifier.urihttp://hdl.handle.net/10722/232396-
dc.descriptionPoster Session 4 - Aortic valve disease: no. P3704-
dc.descriptionThis journal suppl. entitled: ESC Congress 2016 27 - 31 August Rome, Italy-
dc.description.abstractBACKGROUND: Tricuspid annuloplasty (TA) is increasingly performed during left heart valve surgery but the postoperative clinical outcome is poor. PURPOSE: The aim of this study was to determine whether residual pulmonary hypertension (PHT) contributes to the adverse outcome. METHODS: 137 patients (age, 61±11 years; men, 30%) who underwent TA during left-side valve surgery were enrolled. The mean pulmonary artery systolic pressure (PASP) before surgery was 49±13mmHg and 32±15mmHg following surgery. Patients were divided into three groups according to postoperative PASP: no residual PHT (n=78, 57%), mild residual PHT (n=43, 31%), or significant residual PHT (n=16, 12%). RESULTS: A preoperative larger RV geometry and TV tethering area were associated with mild or significant residual PHT. A total of 24 adverse events (20 heart failure and 4 cardiovascular death) occurred during a median follow-up of 25 months. Kaplan-Meier survival curve demonstrated that patients with significant residual PHT had the highest percentage of adverse events followed by those with mild residual PHT. Patients with no residual PHT had a very low risk of adverse events. Multivariable Cox regression analysis revealed that both mild (hazard ratio=4.94; 95% confidence interval=1.34–18.16; P=0.02) and significant residual PHT (hazard ratio=8.67; 95% confidence interval=2.43–30.98; P<0.01) were independent factors associated with adverse events. CONCLUSIONS: The present study demonstrated that 43% of patients who underwent TA had residual PHT. The presence of mild or significant residual PHT was associated with adverse events in these patients.-
dc.languageeng-
dc.publisherOxford University Press. The Journal's web site is located at http://eurheartj.oxfordjournals.org/-
dc.relation.ispartofEuropean Heart Journal-
dc.rightsPre-print: Journal Title] ©: [year] [owner as specified on the article] Published by Oxford University Press [on behalf of xxxxxx]. All rights reserved. Pre-print (Once an article is published, preprint notice should be amended to): This is an electronic version of an article published in [include the complete citation information for the final version of the Article as published in the print edition of the Journal.] Post-print: This is a pre-copy-editing, author-produced PDF of an article accepted for publication in [insert journal title] following peer review. The definitive publisher-authenticated version [insert complete citation information here] is available online at: xxxxxxx [insert URL that the author will receive upon publication here].-
dc.titlePrevalence, predictors and clinical outcome of residual pulmonary hypertension following tricuspid annuloplasty-
dc.typeConference_Paper-
dc.identifier.emailLiu, J: liujuhua@hku.hk-
dc.identifier.emailTse, HF: hftse@hkucc.hku.hk-
dc.identifier.emailYiu, KH: khkyiu@hku.hk-
dc.identifier.authorityTse, HF=rp00428-
dc.identifier.authorityYiu, KH=rp01490-
dc.identifier.doi10.1093/eurheartj/ehw433-
dc.identifier.hkuros263234-
dc.identifier.volume37-
dc.identifier.issuesuppl. 1-
dc.identifier.spage752-
dc.identifier.epage752-
dc.publisher.placeUnited Kingdom-

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