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Article: Gender disparity of hepatocellular carcinoma: role of hepatitis B virus X protein and androgen receptor

TitleGender disparity of hepatocellular carcinoma: role of hepatitis B virus X protein and androgen receptor
Authors
Issue Date2016
PublisherHong Kong Academy of Medicine Press. The Journal's web site is located at http://www.hkmj.org/
Citation
Hong Kong Medical Journal, 2016, v. 22 n. 3, suppl 4, p. 43-47 How to Cite?
AbstractKey Messages 1. The natural COOH-terminal truncated HBx was more frequently detected in hepatocellular carcinoma (HCC) in male than female patients. 2. There was no significant clinicopathological correlation with the HBx status or remarkable changes in androgen receptor (AR) expression in the presence of different truncated HBx mutants compared with full-length HBx. 3. Lower expression of AR was associated with more aggressive tumour phenotype and a higher metastatic potential of HCC.
Persistent Identifierhttp://hdl.handle.net/10722/232160
ISSN
2015 Impact Factor: 0.887
2015 SCImago Journal Rankings: 0.279

 

DC FieldValueLanguage
dc.contributor.authorChiu, YT-
dc.contributor.authorNg, IOL-
dc.date.accessioned2016-09-20T05:28:08Z-
dc.date.available2016-09-20T05:28:08Z-
dc.date.issued2016-
dc.identifier.citationHong Kong Medical Journal, 2016, v. 22 n. 3, suppl 4, p. 43-47-
dc.identifier.issn1024-2708-
dc.identifier.urihttp://hdl.handle.net/10722/232160-
dc.description.abstractKey Messages 1. The natural COOH-terminal truncated HBx was more frequently detected in hepatocellular carcinoma (HCC) in male than female patients. 2. There was no significant clinicopathological correlation with the HBx status or remarkable changes in androgen receptor (AR) expression in the presence of different truncated HBx mutants compared with full-length HBx. 3. Lower expression of AR was associated with more aggressive tumour phenotype and a higher metastatic potential of HCC.-
dc.languageeng-
dc.publisherHong Kong Academy of Medicine Press. The Journal's web site is located at http://www.hkmj.org/-
dc.relation.ispartofHong Kong Medical Journal-
dc.rightsHong Kong Medical Journal. Copyright © Hong Kong Academy of Medicine Press.-
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License-
dc.titleGender disparity of hepatocellular carcinoma: role of hepatitis B virus X protein and androgen receptor-
dc.typeArticle-
dc.identifier.emailChiu, YT: ellechiu@pathology.hku.hk-
dc.identifier.emailNg, IOL: iolng@hku.hk-
dc.identifier.authorityNg, IOL=rp00335-
dc.description.naturepublished_or_final_version-
dc.identifier.pmid27390010-
dc.identifier.hkuros264753-
dc.identifier.volume22-
dc.identifier.issue3, suppl 4-
dc.identifier.spage43-
dc.identifier.epage47-
dc.publisher.placeHong Kong-

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