File Download
Supplementary

Conference Paper: Molecular pathogenesis of hepatocellular carcinoma

TitleMolecular pathogenesis of hepatocellular carcinoma
Authors
Issue Date2013
PublisherKorean Association for the Study of the Liver.
Citation
19th Annual Meeting of the Korean Association for the Study of the Liver (KASL), Seoul, Korea, 14-15 Jun 2013 How to Cite?
AbstractHepatocarcinogenesis is a multistep process evolving from chronic hepatitis and cirrhosis to dysplastic nodules and ultimately hepatocellular carcinoma. Recent advances in molecular methods have led to a growing understanding of the underlying mechanisms of hepatocarcinogenesis. Hepatocarcinogenesis is closely associated with allelic losses, chromosomal changes, gene mutations, and epigenetic alterations. Allelic losses show a stepwise increase at different stages of hepatocarcinogenesis. Chromosomal, genetic, and epigenetic abnormalities can lead to deregulation in many cell signaling pathways implicated in tumour proliferation, progression, and survival. Discoveries and insight into these complex pathways have created opportunities for targeted agents and new therapeutic approaches for this malignant disease. More recent evidence also suggests the involvement of aberrant microRNA expression and the concept of liverspecific cancer stem cells in hepatocarcinogenesis. Detailed undeㄴstanding of the molecular pathogenesis is crucial for the development of new therapeutic approaches against hepatocellular carcinoma. This talk summarises the molecular mechanisms currently implicated in the pathogenesis of hepatocellular carcinoma and their potential roles in improving the clinical management of this disease.
DescriptionPowerpoint presentation with video (SYMPOSIUM 3 : KASL-KLCSG Joint Symposium on HCC)
Persistent Identifierhttp://hdl.handle.net/10722/228306

 

DC FieldValueLanguage
dc.contributor.authorNg, IOL-
dc.date.accessioned2016-08-09T02:26:51Z-
dc.date.available2016-08-09T02:26:51Z-
dc.date.issued2013-
dc.identifier.citation19th Annual Meeting of the Korean Association for the Study of the Liver (KASL), Seoul, Korea, 14-15 Jun 2013-
dc.identifier.urihttp://hdl.handle.net/10722/228306-
dc.descriptionPowerpoint presentation with video (SYMPOSIUM 3 : KASL-KLCSG Joint Symposium on HCC)-
dc.description.abstractHepatocarcinogenesis is a multistep process evolving from chronic hepatitis and cirrhosis to dysplastic nodules and ultimately hepatocellular carcinoma. Recent advances in molecular methods have led to a growing understanding of the underlying mechanisms of hepatocarcinogenesis. Hepatocarcinogenesis is closely associated with allelic losses, chromosomal changes, gene mutations, and epigenetic alterations. Allelic losses show a stepwise increase at different stages of hepatocarcinogenesis. Chromosomal, genetic, and epigenetic abnormalities can lead to deregulation in many cell signaling pathways implicated in tumour proliferation, progression, and survival. Discoveries and insight into these complex pathways have created opportunities for targeted agents and new therapeutic approaches for this malignant disease. More recent evidence also suggests the involvement of aberrant microRNA expression and the concept of liverspecific cancer stem cells in hepatocarcinogenesis. Detailed undeㄴstanding of the molecular pathogenesis is crucial for the development of new therapeutic approaches against hepatocellular carcinoma. This talk summarises the molecular mechanisms currently implicated in the pathogenesis of hepatocellular carcinoma and their potential roles in improving the clinical management of this disease.-
dc.languageeng-
dc.publisherKorean Association for the Study of the Liver. -
dc.relation.ispartofAnnual Meeting of the Korean Association for the Study of the Liver (KASL)-
dc.titleMolecular pathogenesis of hepatocellular carcinoma-
dc.typeConference_Paper-
dc.identifier.emailNg, IOL: iolng@hku.hk-
dc.identifier.authorityNg, IOL=rp00335-
dc.description.naturelink_to_OA_fulltext-
dc.identifier.hkuros217285-
dc.publisher.placeSeoul, Korea-

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats