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Conference Paper: Pattern on atherosclerosis for coronary, carotid and aortic arteries calcification in rheumatoid arthritis: a multidetector CT study

TitlePattern on atherosclerosis for coronary, carotid and aortic arteries calcification in rheumatoid arthritis: a multidetector CT study
Authors
Issue Date2009
PublisherElsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/jac
Citation
The 58th Annual Scientific Session and i2 Summit: Innovation in Intervention of the American College of Cardiology, Orlando, FL, 29-31 March 2009. In Journal of American College of Cardiology, 2009, v. 53 n. 10S, p. A432, abstract no. 1022-119 How to Cite?
AbstractBackground: Multi-detector computed tomography (MDCT) measured coronary, carotid and aortic artery calcium score (CS) reflecting calcified atherosclerotic plaque (CAP) which are associated with coronary artery disease (CAD) and stroke. This study is designed to evaluate the prevalence and pattern of CS in asymptomatic rheumatoid arthritis (RA) patients compare with controls subjects. Methods: 85 age and sex matched RA patients (mean age 53.9±11.8) and controls (mean age 56.3±10.0) were enrolled. All subjects underwent 64MDCT scan to evaluate CS in coronary, carotid arteries and the aorta. Results: Presence of CAP were more prevalent in RA patients compared to controls in coronary artery (41% vs. 18%, p=0.013), carotid artery (19% vs. 6%, p=0.018) and aorta (64% vs. 12%, p<0.001). The prevalence of calcium was over 90% in RA patients at the age of 60 or above and in 55% of control subjects. After adjustment with age and sex, RA patients had a 5.0, 5.7 and 19.5 risk folds to have CAP in coronary, carotid and aortic artery. Aorta of RA patients had the highest frequency of CS > 0 (63.5%) compared with coronary artery in control subjects (11.8%) and this pattern remained the same upon age stratification (42.9-85.2% in RA patients and 4.2-34.5% in control subjects). Conclusions-RA patients have significantly higher prevalence and extent of CAP compared with age and sex matched controls. In addition, a significant different calcification pattern was noted between RA patients and control subjects.
DescriptionSession - Vascular Disease
This journal suppl. entitled: Abstracts of Original Contributions Presented at the American College of Cardiology 58th Annual Scientific Session and i2 Summit: Innovation in Intervention
Persistent Identifierhttp://hdl.handle.net/10722/223459
ISSN
2015 Impact Factor: 17.759
2015 SCImago Journal Rankings: 10.097

 

DC FieldValueLanguage
dc.contributor.authorYiu, KH-
dc.contributor.authorWang, SL-
dc.contributor.authorMok, TMY-
dc.contributor.authorOoi, CGC-
dc.contributor.authorKhong, PL-
dc.contributor.authorMak, HKF-
dc.contributor.authorLau, WCS-
dc.contributor.authorTse, HF-
dc.date.accessioned2016-02-29T02:50:33Z-
dc.date.available2016-02-29T02:50:33Z-
dc.date.issued2009-
dc.identifier.citationThe 58th Annual Scientific Session and i2 Summit: Innovation in Intervention of the American College of Cardiology, Orlando, FL, 29-31 March 2009. In Journal of American College of Cardiology, 2009, v. 53 n. 10S, p. A432, abstract no. 1022-119-
dc.identifier.issn0735-1097-
dc.identifier.urihttp://hdl.handle.net/10722/223459-
dc.descriptionSession - Vascular Disease-
dc.descriptionThis journal suppl. entitled: Abstracts of Original Contributions Presented at the American College of Cardiology 58th Annual Scientific Session and i2 Summit: Innovation in Intervention-
dc.description.abstractBackground: Multi-detector computed tomography (MDCT) measured coronary, carotid and aortic artery calcium score (CS) reflecting calcified atherosclerotic plaque (CAP) which are associated with coronary artery disease (CAD) and stroke. This study is designed to evaluate the prevalence and pattern of CS in asymptomatic rheumatoid arthritis (RA) patients compare with controls subjects. Methods: 85 age and sex matched RA patients (mean age 53.9±11.8) and controls (mean age 56.3±10.0) were enrolled. All subjects underwent 64MDCT scan to evaluate CS in coronary, carotid arteries and the aorta. Results: Presence of CAP were more prevalent in RA patients compared to controls in coronary artery (41% vs. 18%, p=0.013), carotid artery (19% vs. 6%, p=0.018) and aorta (64% vs. 12%, p<0.001). The prevalence of calcium was over 90% in RA patients at the age of 60 or above and in 55% of control subjects. After adjustment with age and sex, RA patients had a 5.0, 5.7 and 19.5 risk folds to have CAP in coronary, carotid and aortic artery. Aorta of RA patients had the highest frequency of CS > 0 (63.5%) compared with coronary artery in control subjects (11.8%) and this pattern remained the same upon age stratification (42.9-85.2% in RA patients and 4.2-34.5% in control subjects). Conclusions-RA patients have significantly higher prevalence and extent of CAP compared with age and sex matched controls. In addition, a significant different calcification pattern was noted between RA patients and control subjects.-
dc.languageeng-
dc.publisherElsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/jac-
dc.relation.ispartofJournal of American College of Cardiology-
dc.rights© <2009>. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/-
dc.titlePattern on atherosclerosis for coronary, carotid and aortic arteries calcification in rheumatoid arthritis: a multidetector CT study-
dc.typeConference_Paper-
dc.identifier.emailYiu, KH: khkyiu@hku.hk-
dc.identifier.emailMok, TMY: temy@hkucc.hku.hk-
dc.identifier.emailOoi, CGC: cgcooi@hkucc.hku.hk-
dc.identifier.emailKhong, PL: plkhong@hkucc.hku.hk-
dc.identifier.emailMak, HKF: makkf@hkucc.hku.hk-
dc.identifier.emailLau, WCS: cslau@hku.hk-
dc.identifier.emailTse, HF: hftse@hkucc.hku.hk-
dc.identifier.authorityYiu, KH=rp01490-
dc.identifier.authorityMok, TMY=rp00490-
dc.identifier.authorityKhong, PL=rp00467-
dc.identifier.authorityMak, HKF=rp00533-
dc.identifier.authorityLau, WCS=rp01348-
dc.identifier.authorityTse, HF=rp00428-
dc.description.naturelink_to_OA_fulltext-
dc.identifier.doi10.1016/j.jacc.2009.01.022-
dc.identifier.hkuros160320-
dc.identifier.volume53-
dc.identifier.issue10S-
dc.identifier.spageA432, abstract no. 1022-119-
dc.identifier.epageA432, abstract no. 1022-119-
dc.publisher.placeUnited States-

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