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  Patent History
  • Application
    ZL200980150076.X 2009-10-09
  • Publication
    CN 102483414 2012-05-30

published patent: Cadherin-17 as diagnostic marker and therapeutic target for liver cancer

TitleCadherin-17 as diagnostic marker and therapeutic target for liver cancer
Priority Date2009-10-09 PCT/CN2009001117
2008-10-09 US 12/104038P
Inventors
Issue Date2012
Citation
China Published Patent Application CN 102483414. Beijing, PRC: State Intellectual Property Office (SIPO) of the P.R.C., 2012 How to Cite?
AbstractCompositions and methods for diagnosing, treating and/or preventing cancers characterized by CDH17 overexpression based on the detection of CDH17 or the use of CDH17 as a target for therapeutic intervention or prophylactic intervention are provided. Methods for diagnosing and/or monitoring liver cancers using the expressing of CDH17 involve detecting and/or quantitating the CDH17 protein or encoding nucleic acids (DNA or RNA) in a biological sample such as urine from the subject. Methods for treating liver cancers using CDH17 as a target and of sensitizing cells with aberrant expression of CDH17 have also been developed. The methods include suppression or knockdown of the expression of CDH17 by administering an effective amount of a CDH17 inhibitor.
Persistent Identifierhttp://hdl.handle.net/10722/213665

 

DC FieldValueLanguage
dc.date.accessioned2015-08-11T03:28:48Z-
dc.date.available2015-08-11T03:28:48Z-
dc.date.issued2012-
dc.identifier.citationChina Published Patent Application CN 102483414. Beijing, PRC: State Intellectual Property Office (SIPO) of the P.R.C., 2012-
dc.identifier.urihttp://hdl.handle.net/10722/213665-
dc.description.abstractCompositions and methods for diagnosing, treating and/or preventing cancers characterized by CDH17 overexpression based on the detection of CDH17 or the use of CDH17 as a target for therapeutic intervention or prophylactic intervention are provided. Methods for diagnosing and/or monitoring liver cancers using the expressing of CDH17 involve detecting and/or quantitating the CDH17 protein or encoding nucleic acids (DNA or RNA) in a biological sample such as urine from the subject. Methods for treating liver cancers using CDH17 as a target and of sensitizing cells with aberrant expression of CDH17 have also been developed. The methods include suppression or knockdown of the expression of CDH17 by administering an effective amount of a CDH17 inhibitor.-
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License for public patent documents-
dc.titleCadherin-17 as diagnostic marker and therapeutic target for liver cancer-
dc.typePatent-
dc.identifier.authorityLUK MOON CHING JOHN=rp00349-
dc.identifier.authorityLEE PUI YUE NIKKI=rp00263-
dc.identifier.authorityPOON TUNG PING RONNIE=rp00446-
dc.identifier.authorityFAN SHEUNG TAT=rp00355-
dc.description.naturepublished_or_final_version-
dc.contributor.inventorLUK MOON CHING JOHN-
dc.contributor.inventorLEE PUI YUE NIKKI-
dc.contributor.inventorLIU LINGXIAO-
dc.contributor.inventorPOON TUNG PING RONNIE-
dc.contributor.inventorFAN SHEUNG TAT-
patents.identifier.applicationZL200980150076.X-
patents.identifier.applicationCN 20098150076-
patents.description.assigneeUNIV HONG KONG -
patents.description.countryChina, PRC-
patents.date.publication2012-05-30-
patents.identifier.hkutechidSurg-2008-00285-7-
patents.date.application2009-10-09-
patents.date.priority2009-10-09 PCT/CN2009001117-
patents.date.priority2008-10-09 US 12/104038P-
patents.description.cccn-
patents.identifier.publicationCN 102483414-
patents.relation.familyEP 2342568 (A1) 2011-07-13 -
patents.relation.familyUS 2010092978 (A1) 2010-04-15-
patents.relation.familyWO 2010040277 (A1) 2010-04-15-
patents.description.kindA-
patents.typePatent_published-

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