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  Patent History
  • Application
    US 12/569386 2009-09-29
  • Publication
    US 2010092978 2010-04-15

published patent: CADHERIN-17 AS DIAGNOSTIC MARKER AND THERAPEUTIC TARGET FOR LIVER CANCER

TitleCADHERIN-17 AS DIAGNOSTIC MARKER AND THERAPEUTIC TARGET FOR LIVER CANCER
Priority Date2009-09-29 US 12/569386
2008-10-09 US 12/104038P
Inventors
Issue Date2010
Citation
US Published patent application US 2010092978. Washington, DC: US Patent and Trademark Office (USPTO), 2010 How to Cite?
AbstractCompositions and methods for diagnosing, treating and/or preventing cancers characterized by CDH17 overexpression based on the detection of CDH17 or the use of CDH17 as a target for therapeutic intervention or prophylactic intervention are provided. Methods for diagnosing and/or monitoring liver cancers using the expressing of CDH17 involve detecting and/or quantitating the CDH17 protein or encoding nucleic acids (DNA or RNA) in a biological sample such as urine from the subject. Methods for treating liver cancers using CDH17 as a target and of sensitizing cells with aberrant expression of CDH17 have also been developed. The methods include suppression or knockdown of the expression of CDH17 by administering an effective amount of a CDH17 inhibitor.
Persistent Identifierhttp://hdl.handle.net/10722/176995

 

DC FieldValueLanguage
dc.date.accessioned2012-11-30T08:38:54Z-
dc.date.available2012-11-30T08:38:54Z-
dc.date.issued2010-
dc.identifier.citationUS Published patent application US 2010092978. Washington, DC: US Patent and Trademark Office (USPTO), 2010en_HK
dc.identifier.urihttp://hdl.handle.net/10722/176995-
dc.description.abstractCompositions and methods for diagnosing, treating and/or preventing cancers characterized by CDH17 overexpression based on the detection of CDH17 or the use of CDH17 as a target for therapeutic intervention or prophylactic intervention are provided. Methods for diagnosing and/or monitoring liver cancers using the expressing of CDH17 involve detecting and/or quantitating the CDH17 protein or encoding nucleic acids (DNA or RNA) in a biological sample such as urine from the subject. Methods for treating liver cancers using CDH17 as a target and of sensitizing cells with aberrant expression of CDH17 have also been developed. The methods include suppression or knockdown of the expression of CDH17 by administering an effective amount of a CDH17 inhibitor.en_HK
dc.relation.isreferencedbyWO 2011127467 (A1) 2011-10-13en_HK
dc.relation.isreferencedbyUS 2011195871 (A1) 2011-08-11en_HK
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License For Public Patent Documentsen_US
dc.titleCADHERIN-17 AS DIAGNOSTIC MARKER AND THERAPEUTIC TARGET FOR LIVER CANCERen_HK
dc.typePatenten_US
dc.description.naturepublished_or_final_versionen_US
dc.contributor.inventorLuk, JMCen_HK
dc.contributor.inventorLee Pui Yue Nikkien_HK
dc.contributor.inventorLiu Lingxiaoen_HK
dc.contributor.inventorPoon, RTPen_HK
dc.contributor.inventorFan, STen_HK
patents.identifier.applicationUS 12/569386en_HK
patents.description.assigneeUNIV HONG KONG [HK]en_HK
patents.description.countryUnited States of Americaen_HK
patents.date.publication2010-04-15en_HK
patents.identifier.hkutechidSurg-2008-00285-1-
patents.date.application2009-09-29en_HK
patents.date.priority2009-09-29 US 12/569386en_HK
patents.date.priority2008-10-09 US 12/104038Pen_HK
patents.description.ccUSen_HK
patents.identifier.publicationUS 2010092978en_HK
patents.relation.familyCN 102483414 (A) 2012-05-30en_HK
patents.relation.familyEP 2342568 (A1) 2011-07-13en_HK
patents.relation.familyUS 2010092978 (A1) 2010-04-15en_HK
patents.relation.familyWO 2010040277 (A1) 2010-04-15en_HK
patents.description.kindA1en_HK
patents.typePatent_publisheden_HK

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