File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)
Supplementary

Conference Paper: Recognition of membrane receptor by atomic force microscopy

TitleRecognition of membrane receptor by atomic force microscopy
Authors
KeywordsMembrane protein
AFM
AT1 receptor
Issue Date2007
Citation
Proceedings of the 2nd IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE NEMS 2007, 2007, p. 1133-1136 How to Cite?
AbstractMembrane receptors play important roles in the signal pathway to regulate cell functions, and therefore, they are usually the main drug targets. However, the study of cell membrane receptors in situ on molecular level is difficult due to the current technical limitations. The recent development of atomic force microscopy (AFM) opens a new way to study the functionalities of cell membrane receptors. In this paper, techniques involving the use of AFM to probe the membrane proteins are introduced. The technique for characterizing specific single receptor using the functionalized AFM tip is discussed. An example of probing angiotensin II type 1 (AT1) receptor on sensory neuron's membrane is also given in this paper. © 2007 IEEE.
Persistent Identifierhttp://hdl.handle.net/10722/212937

 

DC FieldValueLanguage
dc.contributor.authorLi, Guangyong-
dc.contributor.authorXi, Ning-
dc.contributor.authorWang, Donna H.-
dc.date.accessioned2015-07-28T04:05:30Z-
dc.date.available2015-07-28T04:05:30Z-
dc.date.issued2007-
dc.identifier.citationProceedings of the 2nd IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE NEMS 2007, 2007, p. 1133-1136-
dc.identifier.urihttp://hdl.handle.net/10722/212937-
dc.description.abstractMembrane receptors play important roles in the signal pathway to regulate cell functions, and therefore, they are usually the main drug targets. However, the study of cell membrane receptors in situ on molecular level is difficult due to the current technical limitations. The recent development of atomic force microscopy (AFM) opens a new way to study the functionalities of cell membrane receptors. In this paper, techniques involving the use of AFM to probe the membrane proteins are introduced. The technique for characterizing specific single receptor using the functionalized AFM tip is discussed. An example of probing angiotensin II type 1 (AT1) receptor on sensory neuron's membrane is also given in this paper. © 2007 IEEE.-
dc.languageeng-
dc.relation.ispartofProceedings of the 2nd IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE NEMS 2007-
dc.subjectMembrane protein-
dc.subjectAFM-
dc.subjectAT1 receptor-
dc.titleRecognition of membrane receptor by atomic force microscopy-
dc.typeConference_Paper-
dc.description.natureLink_to_subscribed_fulltext-
dc.identifier.doi10.1109/NEMS.2007.352217-
dc.identifier.scopuseid_2-s2.0-34548137661-
dc.identifier.spage1133-
dc.identifier.epage1136-

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats