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Article: Live birth and cumulative live birth rates in expected poor ovarian responders defined by the Bologna criteria following IVF/ICSI treatment

TitleLive birth and cumulative live birth rates in expected poor ovarian responders defined by the Bologna criteria following IVF/ICSI treatment
Authors
Issue Date2015
PublisherPublic Library of Science. The Journal's web site is located at http://www.plosone.org/home.action
Citation
PLoS One, 2015, v. 10 n. 3, p. Article no. e0119149 How to Cite?
AbstractObjective: To determine the live birth and cumulative live birth rates of expected poor ovarian responders according to the Bologna criteria and to compare their outcomes with those of expected normal responders Design: Retrospective analysis Setting: University infertility clinic Patients: A total of 1,152 subfertile women undergoing their first in vitro fertilization (IVF) cycle Interventions: Women were classified into 4 groups according to the Bologna criteria for comparison Main Outcome Measure(s): Live birth and cumulative live birth rates Results: Women with expected poor response (POR) had the lowest live birth rate than the other 3 groups (23.8%, p = 0.031). Cumulative live birth rates were significantly lower in those with expected POR than those with expected normal ovarian response (NOR) (35.8% vs 62.8%, p<0.0001). In the subgroup analysis, the cumulative live birth rates in expected PORs were significantly lower in those who had ≤3 oocytes retrieved (18.6% for ≤3 oocytes vs 44.0% for >3 oocytes, p = 0.006) whereas the live birth rates in fresh cycle did not differ (17.8% vs 30.9%, p = 0.108). Conclusion: Women who were expected POR according to the Bologna criteria had lower live birth and cumulative live birth than expected NOR but they still can achieve reasonable treatment outcomes and IVF treatment should not be precluded. © 2015 Chai et al.
Persistent Identifierhttp://hdl.handle.net/10722/212035
ISSN
2015 Impact Factor: 3.057
2015 SCImago Journal Rankings: 1.395
ISI Accession Number ID
Errata

 

DC FieldValueLanguage
dc.contributor.authorChai, J-
dc.contributor.authorLee, VC-
dc.contributor.authorYeung, TW-
dc.contributor.authorLi, RHW-
dc.contributor.authorHo, PC-
dc.contributor.authorNg, EHY-
dc.date.accessioned2015-07-21T02:20:15Z-
dc.date.available2015-07-21T02:20:15Z-
dc.date.issued2015-
dc.identifier.citationPLoS One, 2015, v. 10 n. 3, p. Article no. e0119149-
dc.identifier.issn1932-6203-
dc.identifier.urihttp://hdl.handle.net/10722/212035-
dc.description.abstractObjective: To determine the live birth and cumulative live birth rates of expected poor ovarian responders according to the Bologna criteria and to compare their outcomes with those of expected normal responders Design: Retrospective analysis Setting: University infertility clinic Patients: A total of 1,152 subfertile women undergoing their first in vitro fertilization (IVF) cycle Interventions: Women were classified into 4 groups according to the Bologna criteria for comparison Main Outcome Measure(s): Live birth and cumulative live birth rates Results: Women with expected poor response (POR) had the lowest live birth rate than the other 3 groups (23.8%, p = 0.031). Cumulative live birth rates were significantly lower in those with expected POR than those with expected normal ovarian response (NOR) (35.8% vs 62.8%, p<0.0001). In the subgroup analysis, the cumulative live birth rates in expected PORs were significantly lower in those who had ≤3 oocytes retrieved (18.6% for ≤3 oocytes vs 44.0% for >3 oocytes, p = 0.006) whereas the live birth rates in fresh cycle did not differ (17.8% vs 30.9%, p = 0.108). Conclusion: Women who were expected POR according to the Bologna criteria had lower live birth and cumulative live birth than expected NOR but they still can achieve reasonable treatment outcomes and IVF treatment should not be precluded. © 2015 Chai et al.-
dc.languageeng-
dc.publisherPublic Library of Science. The Journal's web site is located at http://www.plosone.org/home.action-
dc.relation.ispartofPLoS One-
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License-
dc.titleLive birth and cumulative live birth rates in expected poor ovarian responders defined by the Bologna criteria following IVF/ICSI treatment-
dc.typeArticle-
dc.identifier.emailChai, J: jchai@hkucc.hku.hk-
dc.identifier.emailLi, RHW: raymondli@hku.hk-
dc.identifier.emailHo, PC: pcho@hku.hk-
dc.identifier.emailNg, EHY: nghye@hku.hk-
dc.identifier.authorityChai, J=rp00241-
dc.identifier.authorityLi, RHW=rp01649-
dc.identifier.authorityHo, PC=rp00325-
dc.identifier.authorityNg, EHY=rp00426-
dc.description.naturepublished_or_final_version-
dc.identifier.doi10.1371/journal.pone.0119149-
dc.identifier.pmid25748478-
dc.identifier.scopuseid_2-s2.0-84929120389-
dc.identifier.hkuros244730-
dc.identifier.volume10-
dc.identifier.issue3-
dc.identifier.spageArticle no. e0119149-
dc.identifier.epageArticle no. e0119149-
dc.identifier.isiWOS:000350689400051-
dc.publisher.placeUnited States-
dc.relation.erratumdoi:10.1371/journal.pone.0131334-

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