Patent History
  • Application
    US 12/4078742 2013-11-13
  • Granted
    US 20140142080
Supplementary

Patent: NOVEL GOLD(III) COMPLEXES CONTAINING N-HETEROCYCLIC CARBENE LIGAND, SYNTHESIS, AND THEIR APPLICATIONS IN CANCER TREATMENT AND THIOL DETECTION

TitleNOVEL GOLD(III) COMPLEXES CONTAINING N-HETEROCYCLIC CARBENE LIGAND, SYNTHESIS, AND THEIR APPLICATIONS IN CANCER TREATMENT AND THIOL DETECTION
Granted PatentUS 20140142080
US 8828984
Priority Date2013-11-13 US 12/4078742
2012-11-19 US 12/1728039P
Inventors
Issue Date2014
Citation
US Published patent application US 20140142080. Washington, DC: US Patent and Trademark Office (USPTO), 2014 How to Cite?
AbstractProvided herein is a method of synthesis of Au(III)-NHC complexes, a pharmaceutical composition comprises thereof. Also provided herein are the methods for the treatment and prevention of cancer/tumor in patients in need thereof by the administration of the Au(III)-NHC complexes. Also provided is method of detecting thiol in a biological system. The Au(III)-NHC complexes possess anticancer activity such as the induction of cell death, inhibition of cellular proliferation, inhibition of thioredoxin reductase activity, and inhibition of tumor growth in vivo.
Persistent Identifierhttp://hdl.handle.net/10722/208121

 

DC FieldValueLanguage
dc.date.accessioned2015-02-12T04:33:18Z-
dc.date.available2015-02-12T04:33:18Z-
dc.date.issued2014en_US
dc.identifier.citationUS Published patent application US 20140142080. Washington, DC: US Patent and Trademark Office (USPTO), 2014en_US
dc.identifier.urihttp://hdl.handle.net/10722/208121-
dc.description.abstractProvided herein is a method of synthesis of Au(III)-NHC complexes, a pharmaceutical composition comprises thereof. Also provided herein are the methods for the treatment and prevention of cancer/tumor in patients in need thereof by the administration of the Au(III)-NHC complexes. Also provided is method of detecting thiol in a biological system. The Au(III)-NHC complexes possess anticancer activity such as the induction of cell death, inhibition of cellular proliferation, inhibition of thioredoxin reductase activity, and inhibition of tumor growth in vivo.en_US
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License for public patent documentsen_US
dc.titleNOVEL GOLD(III) COMPLEXES CONTAINING N-HETEROCYCLIC CARBENE LIGAND, SYNTHESIS, AND THEIR APPLICATIONS IN CANCER TREATMENT AND THIOL DETECTIONen_US
dc.typePatenten_US
dc.identifier.authorityCHE CHI MING=rp00670en_US
dc.description.naturepublished_or_final_versionen_US
dc.contributor.inventorChe, CMen_US
dc.contributor.inventorZou, TTen_US
patents.identifier.applicationUS 12/4078742en_US
patents.identifier.grantedUS 20140142080-
patents.identifier.grantedUS 8828984-
patents.description.assigneeUNIV HONG KONG [CN]en_US
patents.description.countryUnited States of Americaen_US
patents.date.publication2014-05-22en_US
patents.identifier.hkutechidChm-2012-00451-1-
patents.date.application2013-11-13en_US
patents.date.priority2013-11-13 US 12/4078742en_US
patents.date.priority2012-11-19 US 12/1728039Pen_US
patents.description.ccusen_US
patents.relation.familyUS 8828984 (B2) 2014-09-09en_US
patents.relation.familyWO 2014075394 (A1) 2014-05-22en_US
patents.description.kindA1en_US

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats