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Article: Correlates of insight with symptomatology and executive function in patients with first-episode schizophrenia-spectrum disorder: A longitudinal perspective

TitleCorrelates of insight with symptomatology and executive function in patients with first-episode schizophrenia-spectrum disorder: A longitudinal perspective
Authors
KeywordsSymptomatology
First-episode schizophrenia spectrum disorder
Executive function
Insight
Issue Date2014
Citation
Psychiatry Research, 2014, v. 216, n. 2, p. 177-184 How to Cite?
AbstractThe present study aimed to examine the relationships of insight with symptomatology and executive function, both cross-sectionally and longitudinally in patients with first-episode schizophrenia-spectrum disorders. Ninety-two medication-naïve patients were recruited and 71 completed the assessments. Insight, symptoms and executive function were assessed at baseline, 6 months and 1 year. Insight was measured with the abridged version of Scale of Unawareness of Mental Disorder (SUMD). Symptoms were assessed using the Positive and Negative Syndrome Scale (PANSS). Executive function was measured with the Modified Wisconsin Card Sorting Test (MCST). The most significant improvement of insight and symptomatology was found over the first 6 months, whereas the perseverative errors of MCST were significantly improved between 6 and 12 months. Differential correlations of perseverative errors of the MCST and PANSS scores with SUMD were found at different time points. This suggests the involvement of different mechanisms in insight deficit at different stages of the illness. The baseline MCST perseverative errors were correlated significantly with the SUMD total score at 6 months and the change of SUMD scores over the first 6 months. Although the variance explained was small, it suggests better set-shifting capacity facilitates the improvement of insight at an early stage of the illness. © 2013 Elsevier Ireland Ltd.
Persistent Identifierhttp://hdl.handle.net/10722/207088
ISSN
2015 Impact Factor: 2.466
2015 SCImago Journal Rankings: 1.235
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorChan, Sherry Kit Wa-
dc.contributor.authorChan, Kevin Ka Shing-
dc.contributor.authorHui, CLM-
dc.contributor.authorWong, Gloria Hoi Yan-
dc.contributor.authorChang, Wing Chung-
dc.contributor.authorLee, Edwin-
dc.contributor.authorTang, YMJ-
dc.contributor.authorChen, Eric Y H-
dc.date.accessioned2014-12-09T04:31:23Z-
dc.date.available2014-12-09T04:31:23Z-
dc.date.issued2014-
dc.identifier.citationPsychiatry Research, 2014, v. 216, n. 2, p. 177-184-
dc.identifier.issn0165-1781-
dc.identifier.urihttp://hdl.handle.net/10722/207088-
dc.description.abstractThe present study aimed to examine the relationships of insight with symptomatology and executive function, both cross-sectionally and longitudinally in patients with first-episode schizophrenia-spectrum disorders. Ninety-two medication-naïve patients were recruited and 71 completed the assessments. Insight, symptoms and executive function were assessed at baseline, 6 months and 1 year. Insight was measured with the abridged version of Scale of Unawareness of Mental Disorder (SUMD). Symptoms were assessed using the Positive and Negative Syndrome Scale (PANSS). Executive function was measured with the Modified Wisconsin Card Sorting Test (MCST). The most significant improvement of insight and symptomatology was found over the first 6 months, whereas the perseverative errors of MCST were significantly improved between 6 and 12 months. Differential correlations of perseverative errors of the MCST and PANSS scores with SUMD were found at different time points. This suggests the involvement of different mechanisms in insight deficit at different stages of the illness. The baseline MCST perseverative errors were correlated significantly with the SUMD total score at 6 months and the change of SUMD scores over the first 6 months. Although the variance explained was small, it suggests better set-shifting capacity facilitates the improvement of insight at an early stage of the illness. © 2013 Elsevier Ireland Ltd.-
dc.languageeng-
dc.relation.ispartofPsychiatry Research-
dc.subjectSymptomatology-
dc.subjectFirst-episode schizophrenia spectrum disorder-
dc.subjectExecutive function-
dc.subjectInsight-
dc.titleCorrelates of insight with symptomatology and executive function in patients with first-episode schizophrenia-spectrum disorder: A longitudinal perspective-
dc.typeArticle-
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1016/j.psychres.2013.11.028-
dc.identifier.pmid24560612-
dc.identifier.scopuseid_2-s2.0-84897087773-
dc.identifier.hkuros228587-
dc.identifier.volume216-
dc.identifier.issue2-
dc.identifier.spage177-
dc.identifier.epage184-
dc.identifier.eissn1872-7123-
dc.identifier.isiWOS:000335099900003-

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