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  Patent History
  • Application
    US 12/3534774 2012-06-27
  • Publication
    US 20130004980 2013-01-03
Supplementary

published patent: TWO-WAY, PORTABLE RIBOSWITCH MEDIATED GENE EXPRESSION CONTROL DEVICE

TitleTWO-WAY, PORTABLE RIBOSWITCH MEDIATED GENE EXPRESSION CONTROL DEVICE
Priority Date2012-06-27 US 12/3534774
2011-06-30 US 12/1503453P
Inventors
Issue Date2013
Citation
US Published patent application US 20130004980. Washington, DC: US Patent and Trademark Office (USPTO), 2013 How to Cite?
AbstractA regulatable gene expression construct comprising a nucleic acid molecule comprising a two-way riboswitch operably linked to a target sequence. Also provided is a library screening strategy for efficient creation of target-specific riboswitches. A theophylline-repressible and IPTG-inducible riboswitch device achieves portable control of gene expression control in a two-way manner. The default state of target genes is ON; the targets are switched off by adding theophylline, and switched back to the ON-state by adding IPTG without changing growth medium. The riboswitch device regulates gene expression in a portable, adjustable, and two-way manner with a variety of scientific and biotechnological applications.
Persistent Identifierhttp://hdl.handle.net/10722/206617

 

DC FieldValueLanguage
dc.date.accessioned2014-11-21T08:05:34Z-
dc.date.available2014-11-21T08:05:34Z-
dc.date.issued2013en_US
dc.identifier.citationUS Published patent application US 20130004980. Washington, DC: US Patent and Trademark Office (USPTO), 2013en_US
dc.identifier.urihttp://hdl.handle.net/10722/206617-
dc.description.abstractA regulatable gene expression construct comprising a nucleic acid molecule comprising a two-way riboswitch operably linked to a target sequence. Also provided is a library screening strategy for efficient creation of target-specific riboswitches. A theophylline-repressible and IPTG-inducible riboswitch device achieves portable control of gene expression control in a two-way manner. The default state of target genes is ON; the targets are switched off by adding theophylline, and switched back to the ON-state by adding IPTG without changing growth medium. The riboswitch device regulates gene expression in a portable, adjustable, and two-way manner with a variety of scientific and biotechnological applications.en_US
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License for public patent documentsen_US
dc.titleTWO-WAY, PORTABLE RIBOSWITCH MEDIATED GENE EXPRESSION CONTROL DEVICEen_US
dc.typePatenten_US
dc.identifier.authorityHUANG, JIAN-DONG=rp00451en_US
dc.description.naturepublished_or_final_versionen_US
dc.contributor.inventorHUANG, JIAN-DONGen_US
dc.contributor.inventorJIN, YEen_US
patents.identifier.applicationUS 12/3534774en_US
patents.description.assigneeUNIV HONG KIONG [CN]; HUANG JIAN-DONG [CN]; JIN YE [CN]en_US
patents.description.countryUnited States of Americaen_US
patents.date.publication2013-01-03en_US
patents.identifier.hkutechidBioch-2011-00381-1en_US
patents.date.application2012-06-27en_US
patents.date.priority2012-06-27 US 12/3534774en_US
patents.date.priority2011-06-30 US 12/1503453Pen_US
patents.description.ccusen_US
patents.identifier.publicationUS 20130004980en_US
patents.relation.familyCN 103797118 (A) 2014-05-14en_US
patents.relation.familyEP 2726608 (A1) 2014-05-07en_US
patents.relation.familyWO 2013000278 (A1) 2013-01-03en_US
patents.description.kindA1en_US
patents.typePatent_publisheden_US

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