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  Patent History
  • Application
    PC T/CN2012000891 2012-06-29
  • Publication
    WO 2013000278 2013-01-03
  Patent Family
Supplementary

published patent: TWO-WAY, PORTABLE RIBOSWITCH MEDIATED GENE EXPRESSION CONTROL DEVICE

TitleTWO-WAY, PORTABLE RIBOSWITCH MEDIATED GENE EXPRESSION CONTROL DEVICE
Priority Date2011-06-30 US 12/1503453P
Inventors
Issue Date2013
Citation
WO Published patent application WO 2013000278. World Intellectual Property Organization (WIPO), PatentScope, 2013 How to Cite?
AbstractA regulatable gene expression construct comprising a nucleic acid molecule comprising a two- way riboswitch operably linked to a target sequence. Also provided is a library screening strategy for efficient creation of target-specific riboswitches. A theophylline-repressible and IPTG-inducible riboswitch device achieves portable control of gene expression control in a 'two- way' manner. The default state of target genes is ON; the targets are switched off by adding theophylline, and switched back to the ON-state by adding IPTG without changing growth medium. The riboswitch device regulates gene expression in a portabe, adjustable, and two-way manner with a variety of scientific and biotechnological applications.
Persistent Identifierhttp://hdl.handle.net/10722/195810
References

 

DC FieldValueLanguage
dc.date.accessioned2014-03-12T09:14:30Z-
dc.date.available2014-03-12T09:14:30Z-
dc.date.issued2013-
dc.identifier.citationWO Published patent application WO 2013000278. World Intellectual Property Organization (WIPO), PatentScope, 2013en_US
dc.identifier.urihttp://hdl.handle.net/10722/195810-
dc.description.abstractA regulatable gene expression construct comprising a nucleic acid molecule comprising a two- way riboswitch operably linked to a target sequence. Also provided is a library screening strategy for efficient creation of target-specific riboswitches. A theophylline-repressible and IPTG-inducible riboswitch device achieves portable control of gene expression control in a 'two- way' manner. The default state of target genes is ON; the targets are switched off by adding theophylline, and switched back to the ON-state by adding IPTG without changing growth medium. The riboswitch device regulates gene expression in a portabe, adjustable, and two-way manner with a variety of scientific and biotechnological applications.en_US
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License for public patent documentsen_US
dc.titleTWO-WAY, PORTABLE RIBOSWITCH MEDIATED GENE EXPRESSION CONTROL DEVICEen_US
dc.typePatenten_US
dc.identifier.authorityHUANG, JIANDONG=rp00451en_US
dc.description.naturepublished_or_final_version-
dc.contributor.inventorHUANG, JIANDONGen_US
dc.contributor.inventorJIN, YEen_US
patents.identifier.applicationPC T/CN2012000891en_US
patents.description.assigneeUNIV HONG KONG [CN]; HUANG JIANDONG [CN]; JIN YE [CN]en_US
patents.description.countryWorld Intellectual Property Organization (WIPO)en_US
patents.date.publication2013-01-03en_US
dc.relation.referencesUS 2009170793 (A1) 2009-07-02en_US
dc.relation.referencesUS 7563601 (B1) 2009-07-21en_US
patents.identifier.hkutechidBioch-2011-00381-2-
patents.date.application2012-06-29en_US
patents.date.priority2011-06-30 US 12/1503453Pen_US
patents.description.ccwoen_US
patents.identifier.publicationWO 2013000278en_US
patents.relation.familyUS 2013004980 (A1) 2013-01-03en_US
patents.description.kindA1en_US
patents.typePatent_publisheden_US

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