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Conference Paper: Regulation of ubiquitination and degradation of CRTC1 transcriptional coactivator by salt-inducible kinase SIK1
Title | Regulation of ubiquitination and degradation of CRTC1 transcriptional coactivator by salt-inducible kinase SIK1 |
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Authors | |
Issue Date | 2014 |
Citation | The 2014 Hong Kong Inter-University Biochemistry Postgraduate Symposium, Hong Kong, 14 June 2014. In Program Booklet, 2014, p. 16, poster no. 7 How to Cite? |
Abstract | cAMP response element (CRE) binding protein (CREB) is a bZIP transcription factor centrally involved in the regulation of cellular proliferation, survival, energy metabolism and stress response. CREB-regulated transcriptional coactivator (CRTC) is an essential factor which potently activates the transcriptional activity of CREB by promoting the recruitment of TAFII130/135. Currently, several kinases and phosphatases are known to regulate the function of CRTCs. For example, salt-inducible kinases (SIKs) belonging to AMPK protein kinase family inhibit the activity of ... |
Description | Poster presentation - Theme 1: Cell biology |
Persistent Identifier | http://hdl.handle.net/10722/203843 |
DC Field | Value | Language |
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dc.contributor.author | Gao, W | en_US |
dc.contributor.author | Jin, DY | en_US |
dc.date.accessioned | 2014-09-19T16:41:16Z | - |
dc.date.available | 2014-09-19T16:41:16Z | - |
dc.date.issued | 2014 | en_US |
dc.identifier.citation | The 2014 Hong Kong Inter-University Biochemistry Postgraduate Symposium, Hong Kong, 14 June 2014. In Program Booklet, 2014, p. 16, poster no. 7 | en_US |
dc.identifier.uri | http://hdl.handle.net/10722/203843 | - |
dc.description | Poster presentation - Theme 1: Cell biology | - |
dc.description.abstract | cAMP response element (CRE) binding protein (CREB) is a bZIP transcription factor centrally involved in the regulation of cellular proliferation, survival, energy metabolism and stress response. CREB-regulated transcriptional coactivator (CRTC) is an essential factor which potently activates the transcriptional activity of CREB by promoting the recruitment of TAFII130/135. Currently, several kinases and phosphatases are known to regulate the function of CRTCs. For example, salt-inducible kinases (SIKs) belonging to AMPK protein kinase family inhibit the activity of ... | - |
dc.language | eng | en_US |
dc.relation.ispartof | Hong Kong Inter-University 2014 Biochemistry Postgraduate Symposium | en_US |
dc.title | Regulation of ubiquitination and degradation of CRTC1 transcriptional coactivator by salt-inducible kinase SIK1 | en_US |
dc.type | Conference_Paper | en_US |
dc.identifier.email | Gao, W: gaoww@hku.hk | en_US |
dc.identifier.email | Jin, DY: dyjin@hku.hk | en_US |
dc.identifier.authority | Jin, DY=rp00452 | en_US |
dc.description.nature | postprint | - |
dc.identifier.hkuros | 240312 | en_US |
dc.identifier.hkuros | 270428 | - |
dc.identifier.spage | 16, poster no. 7 | - |
dc.identifier.epage | 16, poster no. 7 | - |