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Article: Atrial mechanics after surgical repair of tetralogy of Fallot

TitleAtrial mechanics after surgical repair of tetralogy of Fallot
Authors
KeywordsAtrial strain
Speckle tracking echocardiography
Tetralogy of Fallot
Issue Date2015
PublisherBlackwell Publishing, Inc. The Journal's web site is located at http://www.blackwellpublishing.com/journals/ECHO
Citation
Echocardiography, 2015, v. 32 n. 1, p. 126-134 How to Cite?
AbstractBackground Ventricular diastolic dysfunction in patients with repaired tetralogy of Fallot (TOF) may affect atrial mechanics. This study aimed to explore right atrial (RA) and left atrial (LA) mechanics in repaired TOF patients and their relationship with ventricular diastolic function. Methods Fifty-four patients (36 males), aged 17.8 ± 8.3 years, who had undergone TOF repair at 3.9 ± 3.3 years and 40 healthy subjects aged 16.9 ± 6.3 years (P = 0.57) were studied. Right and LA peak positive, peak negative, and total strain, strain rate at ventricular systole (SRs), early diastole (SRed), and atrial contraction (SRac), and electromechanical delay were determined using speckle tracking echocardiography (STE). Ventricular diastolic function was assessed by tissue Doppler imaging and STE. Ventricular volumes and pulmonary regurgitant volume were derived from 3D echocardiography. Results Compared with controls, patients had significantly lower RA and LA peak positive and total strain, SRs, SRed, and SRac (all P < 0.001). The timing of RA (178 ± 33 msec vs. 152 ± 17 msec, P < 0.001) and LA (170 ± 32 msec vs. 152 ± 24 msec, P = 0.006) electromechanical coupling (EMC) was significantly longer in patients than in controls. The RA total strain, SRs, SRed, SRac, and EMC correlated positively with corresponding LA parameters (all P < 0.001). The RA and LA total strain and SRed were associated positively with diastolic annular velocities and strain rates of respective ventricles (all P < 0.05). The LA SRed correlated negatively with pulmonary regurgitant volume (r = -0.33, P = 0.016) and RV end-diastolic volume (r = -0.33, P = 0.015). Conclusion Mechanics of both atria are impaired in patients after repair of TOF and are associated with diastolic performance of the respective ventricles. © 2014, Wiley Periodicals, Inc.
Persistent Identifierhttp://hdl.handle.net/10722/196571
ISSN
2015 Impact Factor: 1.432
2015 SCImago Journal Rankings: 0.596

 

DC FieldValueLanguage
dc.contributor.authorHou, Jen_US
dc.contributor.authorYu, HKen_US
dc.contributor.authorWong, SJen_US
dc.contributor.authorCheung, YFen_US
dc.date.accessioned2014-04-22T08:37:18Z-
dc.date.available2014-04-22T08:37:18Z-
dc.date.issued2015en_US
dc.identifier.citationEchocardiography, 2015, v. 32 n. 1, p. 126-134en_US
dc.identifier.issn0742-2822-
dc.identifier.urihttp://hdl.handle.net/10722/196571-
dc.description.abstractBackground Ventricular diastolic dysfunction in patients with repaired tetralogy of Fallot (TOF) may affect atrial mechanics. This study aimed to explore right atrial (RA) and left atrial (LA) mechanics in repaired TOF patients and their relationship with ventricular diastolic function. Methods Fifty-four patients (36 males), aged 17.8 ± 8.3 years, who had undergone TOF repair at 3.9 ± 3.3 years and 40 healthy subjects aged 16.9 ± 6.3 years (P = 0.57) were studied. Right and LA peak positive, peak negative, and total strain, strain rate at ventricular systole (SRs), early diastole (SRed), and atrial contraction (SRac), and electromechanical delay were determined using speckle tracking echocardiography (STE). Ventricular diastolic function was assessed by tissue Doppler imaging and STE. Ventricular volumes and pulmonary regurgitant volume were derived from 3D echocardiography. Results Compared with controls, patients had significantly lower RA and LA peak positive and total strain, SRs, SRed, and SRac (all P < 0.001). The timing of RA (178 ± 33 msec vs. 152 ± 17 msec, P < 0.001) and LA (170 ± 32 msec vs. 152 ± 24 msec, P = 0.006) electromechanical coupling (EMC) was significantly longer in patients than in controls. The RA total strain, SRs, SRed, SRac, and EMC correlated positively with corresponding LA parameters (all P < 0.001). The RA and LA total strain and SRed were associated positively with diastolic annular velocities and strain rates of respective ventricles (all P < 0.05). The LA SRed correlated negatively with pulmonary regurgitant volume (r = -0.33, P = 0.016) and RV end-diastolic volume (r = -0.33, P = 0.015). Conclusion Mechanics of both atria are impaired in patients after repair of TOF and are associated with diastolic performance of the respective ventricles. © 2014, Wiley Periodicals, Inc.-
dc.languageengen_US
dc.publisherBlackwell Publishing, Inc. The Journal's web site is located at http://www.blackwellpublishing.com/journals/ECHO-
dc.relation.ispartofEchocardiographyen_US
dc.rightsThe definitive version is available at www.blackwell-synergy.com-
dc.subjectAtrial strain-
dc.subjectSpeckle tracking echocardiography-
dc.subjectTetralogy of Fallot-
dc.titleAtrial mechanics after surgical repair of tetralogy of Falloten_US
dc.typeArticleen_US
dc.identifier.emailWong, SJ: sjwong@hku.hken_US
dc.identifier.emailCheung, YF: xfcheung@hku.hken_US
dc.identifier.authorityCheung, YF=rp00382en_US
dc.description.naturelink_to_OA_fulltext-
dc.identifier.doi10.1111/echo.12611en_US
dc.identifier.pmid24697926-
dc.identifier.hkuros228543en_US
dc.identifier.volume32-
dc.identifier.issue1-
dc.identifier.spage126en_US
dc.identifier.epage134en_US
dc.publisher.placeUnited States-

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