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Article: Post-esophagectomy gastric conduit cancers: treatment experiences and literature review

TitlePost-esophagectomy gastric conduit cancers: treatment experiences and literature review
Authors
Issue Date2014
PublisherWiley-Blackwell Publishing Asia. The Journal's web site is located at http://www.blackwellpublishing.com/journals/DES
Citation
Diseases of the Esophagus, 2014, v. 27, n. 2, p. 141-145 How to Cite?
AbstractSummary: Esophagectomy remains the mainstay of treatment for esophageal cancer. The stomach is the commonest organ used to restore intestinal continuity after esophagectomy. Metachronous gastric cancer in the gastric conduit after esophagectomy is rare; the etiology remains unclear. Possible risk factors include Helicobacter pylori infection, biliary or pancreatic reflux and prior radiotherapy. Prognosis of these patients remains poor. Treatment of this particular entity poses unique challenges to the surgeon and oncologist. Early diagnosis by endoscopy may allow endoscopic excision such as endoscopic mucosal resection or endoscopic submucosal dissection. In more advanced cancers, surgery is difficult, reconstruction is complicated, and further radiation may not be feasible because of previous neoadjuvant therapy. In this report, four patients who developed gastric conduit cancers are presented. They were treated with either surgery alone or combined with chemoradiotherapy. All four patients were still alive after at least 21 months, with three patients currently still alive (21-48 months). The literature is also reviewed, in particular addressing the incidence, possible underlying causes, prognosis and options of treatment for this specific clinical scenario. © 2013 Wiley Periodicals, Inc. and the International Society for Diseases of the Esophagus.
Persistent Identifierhttp://hdl.handle.net/10722/195930
ISSN
2015 Impact Factor: 2.146
2015 SCImago Journal Rankings: 0.760
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorHo, Cen_US
dc.contributor.authorTong, DKHen_US
dc.contributor.authorTsang, JSen_US
dc.contributor.authorLaw, SYKen_US
dc.date.accessioned2014-03-21T02:22:37Z-
dc.date.available2014-03-21T02:22:37Z-
dc.date.issued2014en_US
dc.identifier.citationDiseases of the Esophagus, 2014, v. 27, n. 2, p. 141-145en_US
dc.identifier.issn1120-8694-
dc.identifier.urihttp://hdl.handle.net/10722/195930-
dc.description.abstractSummary: Esophagectomy remains the mainstay of treatment for esophageal cancer. The stomach is the commonest organ used to restore intestinal continuity after esophagectomy. Metachronous gastric cancer in the gastric conduit after esophagectomy is rare; the etiology remains unclear. Possible risk factors include Helicobacter pylori infection, biliary or pancreatic reflux and prior radiotherapy. Prognosis of these patients remains poor. Treatment of this particular entity poses unique challenges to the surgeon and oncologist. Early diagnosis by endoscopy may allow endoscopic excision such as endoscopic mucosal resection or endoscopic submucosal dissection. In more advanced cancers, surgery is difficult, reconstruction is complicated, and further radiation may not be feasible because of previous neoadjuvant therapy. In this report, four patients who developed gastric conduit cancers are presented. They were treated with either surgery alone or combined with chemoradiotherapy. All four patients were still alive after at least 21 months, with three patients currently still alive (21-48 months). The literature is also reviewed, in particular addressing the incidence, possible underlying causes, prognosis and options of treatment for this specific clinical scenario. © 2013 Wiley Periodicals, Inc. and the International Society for Diseases of the Esophagus.-
dc.languageengen_US
dc.publisherWiley-Blackwell Publishing Asia. The Journal's web site is located at http://www.blackwellpublishing.com/journals/DES-
dc.relation.ispartofDiseases of the Esophagusen_US
dc.rightsThe definitive version is available at www3.interscience.wiley.com-
dc.titlePost-esophagectomy gastric conduit cancers: treatment experiences and literature reviewen_US
dc.typeArticleen_US
dc.identifier.emailTong, DKH: esodtong@hku.hken_US
dc.identifier.emailLaw, SYK: slaw@hku.hken_US
dc.identifier.authorityLaw, SYK=rp00437en_US
dc.identifier.doi10.1111/dote.12070-
dc.identifier.pmid23551754-
dc.identifier.scopuseid_2-s2.0-84893024824-
dc.identifier.hkuros228316en_US
dc.identifier.volume27en_US
dc.identifier.issue2en_US
dc.identifier.spage141en_US
dc.identifier.epage145en_US
dc.identifier.isiWOS:000331129500008-
dc.publisher.placeAustralia-

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