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Conference Paper: Methylation status at HPV16 E2 binding sites is a potential molecular marker for monitoring patients with Cervical Intraepithelial Neoplasia (CIN)

TitleMethylation status at HPV16 E2 binding sites is a potential molecular marker for monitoring patients with Cervical Intraepithelial Neoplasia (CIN)
Authors
Leung, TWLiu, SSCheung, ANYNgan, HYS
Issue Date2012
PublisherHPV2012.
Citation
The 28th International Papillomavirus Conference (HPV 2012) & Clinical and Public Health Workshops, San Juan, Puerto Rico, Brazil, 30 November-6 December 2012. In HPV2012 Abstract Book: Clinical Sciences, 2012, p. 18 How to Cite?
AbstractOBJECTIVES: There are four E2 binding sites (E2BSs) at the LCR region of HPV16 genome. Binding of E2 protein to different E2BSs may exert either transcriptional activation/repression on E6 and E7 oncoprotein, depending on their distance from the TATA box of the promoter. Methylation status at the E2BSs may affect the relative binding of E2 protein to them and may change during cervical carcinogenesis. Such change in methylation status of the E2BSs may be a potential molecular mark...
DescriptionSession - Clinical Sciences Biomarkers: New and improved for cancer prevention/management of disease
Persistent Identifierhttp://hdl.handle.net/10722/190113

 

DC FieldValueLanguage
dc.contributor.authorLeung, TWen_US
dc.contributor.authorLiu, SSen_US
dc.contributor.authorCheung, ANYen_US
dc.contributor.authorNgan, HYSen_US
dc.date.accessioned2013-09-17T15:09:55Z-
dc.date.available2013-09-17T15:09:55Z-
dc.date.issued2012en_US
dc.identifier.citationThe 28th International Papillomavirus Conference (HPV 2012) & Clinical and Public Health Workshops, San Juan, Puerto Rico, Brazil, 30 November-6 December 2012. In HPV2012 Abstract Book: Clinical Sciences, 2012, p. 18en_US
dc.identifier.urihttp://hdl.handle.net/10722/190113-
dc.descriptionSession - Clinical Sciences Biomarkers: New and improved for cancer prevention/management of disease-
dc.description.abstractOBJECTIVES: There are four E2 binding sites (E2BSs) at the LCR region of HPV16 genome. Binding of E2 protein to different E2BSs may exert either transcriptional activation/repression on E6 and E7 oncoprotein, depending on their distance from the TATA box of the promoter. Methylation status at the E2BSs may affect the relative binding of E2 protein to them and may change during cervical carcinogenesis. Such change in methylation status of the E2BSs may be a potential molecular mark...-
dc.languageengen_US
dc.publisherHPV2012.-
dc.relation.ispartofHPV 2012 & Clinical & Public Health Workshopsen_US
dc.titleMethylation status at HPV16 E2 binding sites is a potential molecular marker for monitoring patients with Cervical Intraepithelial Neoplasia (CIN)en_US
dc.typeConference_Paperen_US
dc.identifier.emailLiu, SS: stephasl@hku.hken_US
dc.identifier.emailCheung, ANY: anycheun@hkucc.hku.hken_US
dc.identifier.emailNgan, HYS: hysngan@hkucc.hku.hken_US
dc.identifier.authorityLiu, SS=rp00372en_US
dc.identifier.authorityCheung, ANY=rp00542en_US
dc.identifier.authorityNgan, HYS=rp00346en_US
dc.description.naturelink_to_OA_fulltext-
dc.identifier.hkuros223411en_US
dc.identifier.spage18-
dc.identifier.epage18-
dc.publisher.placeBrazil-

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