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Book Chapter: Circulating Biomarkers for Esophageal Squamous Cell Carcinoma

TitleCirculating Biomarkers for Esophageal Squamous Cell Carcinoma
Authors
Issue Date2013
PublisherHumana Press
Citation
Circulating Biomarkers for Esophageal Squamous Cell Carcinoma. In Lee, NP ... (et al) (Eds.), New advances on disease biomarkers and molecular targets in biomedicine, p. 85-103. New York, NY: Humana Press, 2013 How to Cite?
AbstractEsophageal cancer is the eighth most common cancer worldwide and esophageal squamous cell carcinoma (ESCC) is the predominant type in Asia. Surgical resection of the tumor is the mainstay treatment for ESCC. Recent advances in neoadjuvant or adjuvant chemotherapy/chemoradiotherapy for treatment of ESCC have significantly improved prognosis. Despite these advancements, survival of some patients still remains poor in particular for those diagnosed at a late stage. In view of the asymptomatic nature of early ESCC and the limitations of currently used diagnostic methods, there is a pressing need to identify circulatory biomarkers to allow noninvasive and early detection of ESCC. In this chapter, we summarize circulating cancer biomarkers including circulatory proteins, microRNAs, and tumor cells that are found to have elevated level in serum and plasma of ESCC patients when compared to healthy subjects. These biomarkers could help improve the diagnostic efficiency of ESCC.
Persistent Identifierhttp://hdl.handle.net/10722/187474
ISSN

 

DC FieldValueLanguage
dc.contributor.authorLai, KKen_US
dc.contributor.authorChan, KTen_US
dc.contributor.authorFatima, Sen_US
dc.contributor.authorLee, NPYen_US
dc.contributor.authorLaw, SYKen_US
dc.date.accessioned2013-08-20T12:50:08Z-
dc.date.available2013-08-20T12:50:08Z-
dc.date.issued2013en_US
dc.identifier.citationCirculating Biomarkers for Esophageal Squamous Cell Carcinoma. In Lee, NP ... (et al) (Eds.), New advances on disease biomarkers and molecular targets in biomedicine, p. 85-103. New York, NY: Humana Press, 2013en_US
dc.identifier.issn9781627034555-
dc.identifier.urihttp://hdl.handle.net/10722/187474-
dc.description.abstractEsophageal cancer is the eighth most common cancer worldwide and esophageal squamous cell carcinoma (ESCC) is the predominant type in Asia. Surgical resection of the tumor is the mainstay treatment for ESCC. Recent advances in neoadjuvant or adjuvant chemotherapy/chemoradiotherapy for treatment of ESCC have significantly improved prognosis. Despite these advancements, survival of some patients still remains poor in particular for those diagnosed at a late stage. In view of the asymptomatic nature of early ESCC and the limitations of currently used diagnostic methods, there is a pressing need to identify circulatory biomarkers to allow noninvasive and early detection of ESCC. In this chapter, we summarize circulating cancer biomarkers including circulatory proteins, microRNAs, and tumor cells that are found to have elevated level in serum and plasma of ESCC patients when compared to healthy subjects. These biomarkers could help improve the diagnostic efficiency of ESCC.-
dc.languageengen_US
dc.publisherHumana Pressen_US
dc.relation.ispartofNew advances on disease biomarkers and molecular targets in biomedicine-
dc.titleCirculating Biomarkers for Esophageal Squamous Cell Carcinomaen_US
dc.typeBook_Chapteren_US
dc.identifier.emailChan, KT: ktchan66@hku.hken_US
dc.identifier.emailLee, NPY: nikkilee@hku.hken_US
dc.identifier.emailLaw, SYK: slaw@hku.hken_US
dc.identifier.authorityLee, NPY=rp00263en_US
dc.identifier.authorityLaw, SYK=rp00437en_US
dc.identifier.doi10.1007/978-1-62703-456-2_6-
dc.identifier.hkuros224883en_US
dc.identifier.hkuros220291-
dc.identifier.spage85en_US
dc.identifier.epage103en_US
dc.publisher.placeNew York, NYen_US

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