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Conference Paper: Proline-rich acidic protein 1 (PRAP1), a novel mitotic arrest deficient 1 (MAD1) interacting partner, suppresses mitotic checkpoint signaling in hepatocellular carcinoma

TitleProline-rich acidic protein 1 (PRAP1), a novel mitotic arrest deficient 1 (MAD1) interacting partner, suppresses mitotic checkpoint signaling in hepatocellular carcinoma
Authors
KeywordsMedical sciences
Oncology
Issue Date2013
PublisherAmerican Association for Cancer Research. The Journal's web site is located at http://cancerres.aacrjournals.org/
Citation
The 104th Annual Meeting of the American Association for Cancer Research (AACR 2013), Washington, DC, PA., 6-10 April 2013. In Cancer Research, 2013, v. 73 n. 8, suppl. 1, abstract no. 572 How to Cite?
AbstractDNA aneuploidy or chromosomal instability is commonly observed in major types of human cancers, and one of the causes for chromosomal instability is defective mitotic checkpoint signaling in cells. Loss of mitotic checkpoint contributes to chromosomal instability, leading to carcinogenesis. The mitotic checkpoint monitors the status of kinetochore-microtubule attachment and delays the onset of anaphase until all kinetochores have been attached with microtubules. Mitotic arrest deficient 1 (MAD1) is key component in mitotic checkpoint signaling. We previously identified a novel isoform of …
DescriptionPoster Presentations - Cell Cycle 1: abstract no. 572
Persistent Identifierhttp://hdl.handle.net/10722/186894
ISSN
2015 Impact Factor: 8.556
2015 SCImago Journal Rankings: 5.372

 

DC FieldValueLanguage
dc.contributor.authorSze, KMFen_US
dc.contributor.authorChu, GKYen_US
dc.contributor.authorMAK, QHYen_US
dc.contributor.authorNg, IOLen_US
dc.date.accessioned2013-08-20T12:23:37Z-
dc.date.available2013-08-20T12:23:37Z-
dc.date.issued2013en_US
dc.identifier.citationThe 104th Annual Meeting of the American Association for Cancer Research (AACR 2013), Washington, DC, PA., 6-10 April 2013. In Cancer Research, 2013, v. 73 n. 8, suppl. 1, abstract no. 572en_US
dc.identifier.issn0008-5472-
dc.identifier.urihttp://hdl.handle.net/10722/186894-
dc.descriptionPoster Presentations - Cell Cycle 1: abstract no. 572-
dc.description.abstractDNA aneuploidy or chromosomal instability is commonly observed in major types of human cancers, and one of the causes for chromosomal instability is defective mitotic checkpoint signaling in cells. Loss of mitotic checkpoint contributes to chromosomal instability, leading to carcinogenesis. The mitotic checkpoint monitors the status of kinetochore-microtubule attachment and delays the onset of anaphase until all kinetochores have been attached with microtubules. Mitotic arrest deficient 1 (MAD1) is key component in mitotic checkpoint signaling. We previously identified a novel isoform of …-
dc.languageengen_US
dc.publisherAmerican Association for Cancer Research. The Journal's web site is located at http://cancerres.aacrjournals.org/-
dc.relation.ispartofCancer Researchen_US
dc.subjectMedical sciences-
dc.subjectOncology-
dc.titleProline-rich acidic protein 1 (PRAP1), a novel mitotic arrest deficient 1 (MAD1) interacting partner, suppresses mitotic checkpoint signaling in hepatocellular carcinomaen_US
dc.typeConference_Paperen_US
dc.identifier.emailSze, KMF: karensze@hkucc.hku.hken_US
dc.identifier.emailChu, GKY: glanice@hku.hken_US
dc.identifier.emailNg, IOL: iolng@hku.hken_US
dc.description.naturelink_to_OA_fulltext-
dc.identifier.doi10.1158/1538-7445.AM2013-572-
dc.identifier.hkuros218911en_US
dc.identifier.volume73-
dc.identifier.issue8, suppl. 1-
dc.publisher.placeUnited States-

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