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Conference Paper: Prognosis after Status Epilepticus

TitlePrognosis after Status Epilepticus
Authors
KeywordsMedical sciences
Psychiatry and neurology
Issue Date2013
PublisherLippincott Williams & Wilkins. The Journal's web site is located at http://www.neurology.org
Citation
The 65th Annual Meeting of the American Academy of Neurology (AAN 2013), San Diego, CA., 16-23 March 2013. In Neurology, 2013, v. 80 n. 1 meeting abstracts, abstract P07.175 How to Cite?
AbstractOBJECTIVE: To determine the clinical characteristics and prognostic factors of status epilepticus (SE) in Hong Kong. BACKGROUND: SE is a neurological emergency with significant mortality and morbidity. There is currently limited data regarding the causes and outcomes of SE in our locality. DESIGN/METHODS: We retrospectively studied the clinical characteristics, clinical outcome of adults diagnosed with convulsive SE and managed at a regional hospital in Hong Kong during January 1st 2007 – December 31st 2011. RESULTS: A total of 38 patients with convulsive SE were identified during the study period. The mean age was 58 years (range 21-92 years) and 61% were males. Underlying cerebrovascular disease (34%), poor compliance to anti-convulsants in patients with known epilepsy (16%) and infection of the central nervous system (11%) were the main causes of convulsive SE. SE was associated with 21% mortality during hospitalization period and 32% mortality within 6-months of admission. Age 65 years, prior history of seizures, a higher blood glucose level during SE and a Status Epilepticus Severity Score (STESS) 4 were associated with 6-month mortality (p<0.05). Multi-variate analysis subsequently identified a STESS 4 as an independent predictor of poor prognosis (p=0.03). CONCLUSIONS: Convulsive SE in adults is most commonly due to underlying cerebrovascular disease and is associated with a high mortality. The STESS is a useful tool in predicting 6-month mortality.
DescriptionSession P07 - Epilepsy: Clinical Epilepsy: abstract P07.175
Abstracts from the AAN Annual Meeting in San Diego were published online only this year, and can be viewed at: www.abstracts2view.com/aan or http://www.neurology.org/content/vol80/1_MeetingAbstracts
Persistent Identifierhttp://hdl.handle.net/10722/182111
ISSN
2015 Impact Factor: 8.166
2015 SCImago Journal Rankings: 3.691

 

DC FieldValueLanguage
dc.contributor.authorYeung, Men_US
dc.contributor.authorFung, FHFen_US
dc.contributor.authorWong, YKen_US
dc.contributor.authorChang, RSKen_US
dc.contributor.authorMak, Wen_US
dc.contributor.authorHon, SFKen_US
dc.contributor.authorCheung, Ren_US
dc.contributor.authorHo, SLen_US
dc.contributor.authorChan, KHen_US
dc.contributor.authorLau, Gen_US
dc.date.accessioned2013-04-17T07:22:00Z-
dc.date.available2013-04-17T07:22:00Z-
dc.date.issued2013en_US
dc.identifier.citationThe 65th Annual Meeting of the American Academy of Neurology (AAN 2013), San Diego, CA., 16-23 March 2013. In Neurology, 2013, v. 80 n. 1 meeting abstracts, abstract P07.175en_US
dc.identifier.issn0028-3878-
dc.identifier.urihttp://hdl.handle.net/10722/182111-
dc.descriptionSession P07 - Epilepsy: Clinical Epilepsy: abstract P07.175-
dc.descriptionAbstracts from the AAN Annual Meeting in San Diego were published online only this year, and can be viewed at: www.abstracts2view.com/aan or http://www.neurology.org/content/vol80/1_MeetingAbstracts-
dc.description.abstractOBJECTIVE: To determine the clinical characteristics and prognostic factors of status epilepticus (SE) in Hong Kong. BACKGROUND: SE is a neurological emergency with significant mortality and morbidity. There is currently limited data regarding the causes and outcomes of SE in our locality. DESIGN/METHODS: We retrospectively studied the clinical characteristics, clinical outcome of adults diagnosed with convulsive SE and managed at a regional hospital in Hong Kong during January 1st 2007 – December 31st 2011. RESULTS: A total of 38 patients with convulsive SE were identified during the study period. The mean age was 58 years (range 21-92 years) and 61% were males. Underlying cerebrovascular disease (34%), poor compliance to anti-convulsants in patients with known epilepsy (16%) and infection of the central nervous system (11%) were the main causes of convulsive SE. SE was associated with 21% mortality during hospitalization period and 32% mortality within 6-months of admission. Age 65 years, prior history of seizures, a higher blood glucose level during SE and a Status Epilepticus Severity Score (STESS) 4 were associated with 6-month mortality (p<0.05). Multi-variate analysis subsequently identified a STESS 4 as an independent predictor of poor prognosis (p=0.03). CONCLUSIONS: Convulsive SE in adults is most commonly due to underlying cerebrovascular disease and is associated with a high mortality. The STESS is a useful tool in predicting 6-month mortality.-
dc.languageengen_US
dc.publisherLippincott Williams & Wilkins. The Journal's web site is located at http://www.neurology.org-
dc.relation.ispartofNeurologyen_US
dc.subjectMedical sciences-
dc.subjectPsychiatry and neurology-
dc.titlePrognosis after Status Epilepticusen_US
dc.typeConference_Paperen_US
dc.identifier.emailWong, YK: debbieyk@hku.hken_US
dc.identifier.emailChang, RSK: richardcsk@gmail.comen_US
dc.identifier.emailMak, W: makwaiwo@hotmail.comen_US
dc.identifier.emailCheung, R: rtcheung@hku.hken_US
dc.identifier.emailHo, SL: slho@hku.hken_US
dc.identifier.emailChan, KH: koonho@hku.hken_US
dc.identifier.emailLau, G: gkklau@hku.hk-
dc.identifier.authorityCheung, R=rp00434en_US
dc.identifier.authorityHo, SL=rp00240en_US
dc.identifier.authorityChan, KH=rp00537en_US
dc.identifier.authorityLau, G=rp01499en_US
dc.description.naturelink_to_OA_fulltext-
dc.identifier.hkuros213854en_US
dc.identifier.volume80-
dc.identifier.issue1 meeting abstracts-
dc.publisher.placeUnited States-

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