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Article: Hepatic progenitor cells: their role and functional significance in the new classification of primary liver cancers

TitleHepatic progenitor cells: their role and functional significance in the new classification of primary liver cancers
Authors
KeywordsClassification
Hepatic progenitor cells
Hepatocarcinogenesis
Hepatocellular carcinoma
Issue Date2013
PublisherS. Karger AG. The Journal's web site is located at http://content.karger.com/ProdukteDB/produkte.asp?Aktion=JournalHome&ProduktNr=255487
Citation
Liver Cancer, 2013, v. 2 n. 2, p. 84-92 How to Cite?
AbstractHepatic progenitor cells (HPCs) are bipotential cells residing in normal liver. Their proliferation is observed in reactive conditions of the liver and in primary liver cancers. The observation that some hepatocellular carcinomas (HCCs) express a biliary-like immunophenotype has led to the identification of HPCs in HCC. Accumulating evidence suggests that HPCs play a role as the cell of origin in a variety of primary liver cancers. This has led to the development of revolutionary concepts in hepatocarcinogenesis. In this article, the role and significance of HPCs in HCC, including its classification, are summarized and discussed.
Persistent Identifierhttp://hdl.handle.net/10722/182050
ISSN

 

DC FieldValueLanguage
dc.contributor.authorLo, RCLen_US
dc.contributor.authorNg, IOLen_US
dc.date.accessioned2013-04-17T07:20:28Z-
dc.date.available2013-04-17T07:20:28Z-
dc.date.issued2013en_US
dc.identifier.citationLiver Cancer, 2013, v. 2 n. 2, p. 84-92en_US
dc.identifier.issn2235-1795-
dc.identifier.urihttp://hdl.handle.net/10722/182050-
dc.description.abstractHepatic progenitor cells (HPCs) are bipotential cells residing in normal liver. Their proliferation is observed in reactive conditions of the liver and in primary liver cancers. The observation that some hepatocellular carcinomas (HCCs) express a biliary-like immunophenotype has led to the identification of HPCs in HCC. Accumulating evidence suggests that HPCs play a role as the cell of origin in a variety of primary liver cancers. This has led to the development of revolutionary concepts in hepatocarcinogenesis. In this article, the role and significance of HPCs in HCC, including its classification, are summarized and discussed.-
dc.languageengen_US
dc.publisherS. Karger AG. The Journal's web site is located at http://content.karger.com/ProdukteDB/produkte.asp?Aktion=JournalHome&ProduktNr=255487-
dc.relation.ispartofLiver Canceren_US
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License-
dc.subjectClassification-
dc.subjectHepatic progenitor cells-
dc.subjectHepatocarcinogenesis-
dc.subjectHepatocellular carcinoma-
dc.titleHepatic progenitor cells: their role and functional significance in the new classification of primary liver cancersen_US
dc.typeArticleen_US
dc.identifier.emailLo, RCL: loregina@hku.hken_US
dc.identifier.emailNg, IOL: iolng@hku.hken_US
dc.identifier.authorityLo, RCL=rp01359en_US
dc.identifier.authorityNg, IOL=rp00335en_US
dc.description.naturepostprint-
dc.identifier.doi10.1159/000343844-
dc.identifier.hkuros213890en_US
dc.identifier.volume2en_US
dc.identifier.issue2-
dc.identifier.spage84-
dc.identifier.epage92-
dc.publisher.placeSwitzerland-

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