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  Patent History
  • Application
    US 11/187160 2005-07-22
  • Granted
    US 7645917 2010-01-12
Supplementary

granted patent: Mutant mice comprising a mutated type II procollagen alpha-1

TitleMutant mice comprising a mutated type II procollagen alpha-1
Granted PatentUS 7645917
Granted Date2010-01-12
Priority Date2005-07-22 US 11/187160
2004-07-26 US 10/591935P
Inventors
Issue Date2010
Citation
US Patent US 7645917. Washington, DC: US Patent and Trademark Office (USPTO), 2010 How to Cite?
AbstractThis invention relates to the production of dual models of Congenital Heart Defects and Hypertrophic Cardiomyopathy with the use of mice which are genetically modified by transgenic (gene-knockout) techniques. The present invention produces knockout mice that show multiple cardiovascular malformations which will serve as a model of cardiovascular diseases for the screening of potential drugs against ventricular remodeling, malignant arrhythmias, primary pulmonary hypertension, and degenerative valvular diseases, and congenital heart disease.
Persistent Identifierhttp://hdl.handle.net/10722/177042

 

DC FieldValueLanguage
dc.date.accessioned2012-11-30T08:38:59Z-
dc.date.available2012-11-30T08:38:59Z-
dc.date.issued2010-
dc.identifier.citationUS Patent US 7645917. Washington, DC: US Patent and Trademark Office (USPTO), 2010en_HK
dc.identifier.urihttp://hdl.handle.net/10722/177042-
dc.description.abstractThis invention relates to the production of dual models of Congenital Heart Defects and Hypertrophic Cardiomyopathy with the use of mice which are genetically modified by transgenic (gene-knockout) techniques. The present invention produces knockout mice that show multiple cardiovascular malformations which will serve as a model of cardiovascular diseases for the screening of potential drugs against ventricular remodeling, malignant arrhythmias, primary pulmonary hypertension, and degenerative valvular diseases, and congenital heart disease.en_HK
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License For Public Patent Documentsen_US
dc.titleMutant mice comprising a mutated type II procollagen alpha-1en_HK
dc.typePatenten_US
dc.description.naturepublished_or_final_versionen_US
dc.contributor.inventorCheah, KSEen_HK
dc.contributor.inventorZhang Janet Chyng-Jiau Len_HK
patents.identifier.applicationUS 11/187160en_HK
patents.identifier.grantedUS 7645917en_HK
patents.description.assigneeUNIV HONG KONG [CN]en_HK
patents.description.countryUnited States of Americaen_HK
patents.date.granted2010-01-12en_HK
patents.date.application2005-07-22en_HK
patents.date.priority2005-07-22 US 11/187160en_HK
patents.date.priority2004-07-26 US 10/591935Pen_HK
patents.description.ccUSen_HK
patents.relation.familyCN 101001948 (A) 2007-07-18en_HK
patents.relation.familyGB 2431657 (A) 2007-05-02en_HK
patents.relation.familyUS 2006031953 (A1) 2006-02-09en_HK
patents.relation.familyUS 7645917 (B2) 2010-01-12en_HK
patents.relation.familyWO 2006010323 (A1) 2006-02-02en_HK
patents.description.kindB2en_HK
patents.typePatent_granteden_HK

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