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Patent History
- ApplicationUS 11/187160 2005-07-22
- GrantedUS 7645917 2010-01-12
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granted patent: Mutant mice comprising a mutated type II procollagen alpha-1
| Title | Mutant mice comprising a mutated type II procollagen alpha-1 |
|---|---|
| Granted Patent | US 7645917 |
| Granted Date | 2010-01-12 |
| Priority Date | 2005-07-22 US 11/187160 2004-07-26 US 10/591935P |
| Inventors | |
| Issue Date | 2010 |
| Citation | US Patent US 7645917. Washington, DC: US Patent and Trademark Office (USPTO), 2010 How to Cite? |
| Abstract | This invention relates to the production of dual models of Congenital Heart Defects and Hypertrophic Cardiomyopathy with the use of mice which are genetically modified by transgenic (gene-knockout) techniques. The present invention produces knockout mice that show multiple cardiovascular malformations which will serve as a model of cardiovascular diseases for the screening of potential drugs against ventricular remodeling, malignant arrhythmias, primary pulmonary hypertension, and degenerative valvular diseases, and congenital heart disease. |
| Persistent Identifier | http://hdl.handle.net/10722/177042 |
| DC Field | Value | Language |
|---|---|---|
| dc.date.accessioned | 2012-11-30T08:38:59Z | - |
| dc.date.available | 2012-11-30T08:38:59Z | - |
| dc.date.issued | 2010 | - |
| dc.identifier.citation | US Patent US 7645917. Washington, DC: US Patent and Trademark Office (USPTO), 2010 | en_HK |
| dc.identifier.uri | http://hdl.handle.net/10722/177042 | - |
| dc.description.abstract | This invention relates to the production of dual models of Congenital Heart Defects and Hypertrophic Cardiomyopathy with the use of mice which are genetically modified by transgenic (gene-knockout) techniques. The present invention produces knockout mice that show multiple cardiovascular malformations which will serve as a model of cardiovascular diseases for the screening of potential drugs against ventricular remodeling, malignant arrhythmias, primary pulmonary hypertension, and degenerative valvular diseases, and congenital heart disease. | en_HK |
| dc.title | Mutant mice comprising a mutated type II procollagen alpha-1 | en_HK |
| dc.type | Patent | en_US |
| dc.description.nature | published_or_final_version | en_US |
| dc.contributor.inventor | Cheah, KSE | en_HK |
| dc.contributor.inventor | Zhang Janet Chyng-Jiau L | en_HK |
| patents.identifier.application | US 11/187160 | en_HK |
| patents.identifier.granted | US 7645917 | en_HK |
| patents.description.assignee | UNIV HONG KONG [CN] | en_HK |
| patents.description.country | United States of America | en_HK |
| patents.date.granted | 2010-01-12 | en_HK |
| patents.date.application | 2005-07-22 | en_HK |
| patents.date.priority | 2005-07-22 US 11/187160 | en_HK |
| patents.date.priority | 2004-07-26 US 10/591935P | en_HK |
| patents.description.cc | US | en_HK |
| patents.relation.family | CN 101001948 (A) 2007-07-18 | en_HK |
| patents.relation.family | GB 2431657 (A) 2007-05-02 | en_HK |
| patents.relation.family | US 2006031953 (A1) 2006-02-09 | en_HK |
| patents.relation.family | US 7645917 (B2) 2010-01-12 | en_HK |
| patents.relation.family | WO 2006010323 (A1) 2006-02-02 | en_HK |
| patents.description.kind | B2 | en_HK |
| patents.type | Patent_granted | en_HK |