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  Patent History
  • Application
    US 08/030081 1993-04-12
  • Granted
    US 6063913 2000-05-16
Supplementary

granted patent: Stable heterologous propagation CFTR protein variant cDNA

TitleStable heterologous propagation CFTR protein variant cDNA
Granted PatentUS 6063913
Granted Date2000-05-16
Priority Date1993-04-12 US 08/030081
1991-09-20 PCT/CA1991000341
1990-09-21 GB19900020632
1989-08-31 US 07/401609
1989-08-24 US 07/399945
1989-08-22 US 07/396894
Inventors
Issue Date2000
Citation
US Patent US 6063913. Washington, DC: US Patent and Trademark Office (USPTO), 2000 How to Cite?
AbstractPCT No. PCT/CA91/00341 Sec. 371 Date Apr. 12, 1993 Sec. 102(e) Date Apr. 12, 1993 PCT Filed Sep. 20, 1991 PCT Pub. No. WO92/05252 PCT Pub. Date Apr. 2, 1992A modified DNA sequence encoding full length cystic fibrosis transmembrane conductance regulator protein is provided to facilitate propagation and/or expression of the protein in living cells and in particular, bacterial cells. The modified DNA sequence comprises at least one of the 13 base pair repeat of exon 6b of the normal gene encoding the conductance regulator protein, as one or more normal nucleotides of the 13 base repeat substituted with an alternate nucleotide which, however, continues to code for the corresponding normal amino acid. Mammalian cells transfected with a vector containing the modified DNA sequence enhances chlorine conductance through the cell wall.
Persistent Identifierhttp://hdl.handle.net/10722/177029
References

 

DC FieldValueLanguage
dc.date.accessioned2012-11-30T08:38:58Z-
dc.date.available2012-11-30T08:38:58Z-
dc.date.issued2000-
dc.identifier.citationUS Patent US 6063913. Washington, DC: US Patent and Trademark Office (USPTO), 2000en_HK
dc.identifier.urihttp://hdl.handle.net/10722/177029-
dc.description.abstractPCT No. PCT/CA91/00341 Sec. 371 Date Apr. 12, 1993 Sec. 102(e) Date Apr. 12, 1993 PCT Filed Sep. 20, 1991 PCT Pub. No. WO92/05252 PCT Pub. Date Apr. 2, 1992A modified DNA sequence encoding full length cystic fibrosis transmembrane conductance regulator protein is provided to facilitate propagation and/or expression of the protein in living cells and in particular, bacterial cells. The modified DNA sequence comprises at least one of the 13 base pair repeat of exon 6b of the normal gene encoding the conductance regulator protein, as one or more normal nucleotides of the 13 base repeat substituted with an alternate nucleotide which, however, continues to code for the corresponding normal amino acid. Mammalian cells transfected with a vector containing the modified DNA sequence enhances chlorine conductance through the cell wall.en_HK
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License For Public Patent Documentsen_US
dc.titleStable heterologous propagation CFTR protein variant cDNAen_HK
dc.typePatenten_US
dc.description.naturepublished_or_final_versionen_US
dc.contributor.inventorTsui, LCen_HK
dc.contributor.inventorRommens, Johanna Men_HK
patents.identifier.applicationUS 08/030081en_HK
patents.identifier.grantedUS 6063913en_HK
patents.description.assigneeHSC RES DEV LP [CA]en_HK
patents.description.countryUnited States of Americaen_HK
patents.date.granted2000-05-16en_HK
dc.relation.referencesUS 4322274 (A) 1982-03-30en_HK
dc.relation.referencesUS 4844893 (A) 1989-07-04en_HK
dc.relation.referencesUS 4847201 (A) 1989-07-11en_HK
dc.relation.referencesUS 4853331 (A) 1989-08-01en_HK
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dc.relation.referencesUS 5240846 (A) 1993-08-31en_HK
dc.relation.referencesEP 0226288 (A3) 1989-06-28en_HK
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dc.relation.referencesWO 9102796 (A1) 1991-03-07en_HK
dc.relation.referencesWO 9110734 (A1) 1991-07-25en_HK
patents.date.application1993-04-12en_HK
patents.date.priority1993-04-12 US 08/030081en_HK
patents.date.priority1991-09-20 PCT/CA1991000341en_HK
patents.date.priority1990-09-21 GB19900020632en_HK
patents.date.priority1989-08-31 US 07/401609en_HK
patents.date.priority1989-08-24 US 07/399945en_HK
patents.date.priority1989-08-22 US 07/396894en_HK
patents.description.ccUSen_HK
patents.relation.familyAT 253633 (T) 2003-11-15en_HK
patents.relation.familyAU 6161690 (A) 1991-04-03en_HK
patents.relation.familyAU 647408 (B2) 1994-03-24en_HK
patents.relation.familyAU 3489193 (A) 1993-09-13en_HK
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patents.relation.familyCA 2144314 (A1) 1994-03-31en_HK
patents.relation.familyCA 2161962 (A1) 1994-12-22en_HK
patents.relation.familyCA 2289222 (A1) 1992-03-19en_HK
patents.relation.familyDE 69034115 (T2) 2004-07-15en_HK
patents.relation.familyDK 0489058 (T3) 2004-03-22en_HK
patents.relation.familyEP 0489058 (A1) 1992-06-10en_HK
patents.relation.familyEP 0549691 (A1) 1993-07-07en_HK
patents.relation.familyEP 0659046 (A1) 1995-06-28en_HK
patents.relation.familyEP 0710123 (A1) 1996-05-08en_HK
patents.relation.familyEP 1418183 (A1) 2004-05-12en_HK
patents.relation.familyES 2210224 (T3) 2004-07-01en_HK
patents.relation.familyIE 903024 (A1) 1991-02-27en_HK
patents.relation.familyIE 20040698 (A1) 2004-12-01en_HK
patents.relation.familyJP H08504092 (A) 1996-05-07en_HK
patents.relation.familyJP 2801085 (B2) 1998-09-21en_HK
patents.relation.familyJP H09500524 (A) 1997-01-21en_HK
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patents.relation.familyJP 3253073 (B2) 2002-02-04en_HK
patents.relation.familyJP H05500306 (A) 1993-01-28en_HK
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patents.relation.familyUS 5240846 (A) 1993-08-31en_HK
patents.relation.familyUS 5434086 (A) 1995-07-18en_HK
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patents.relation.familyUS 5776677 (A) 1998-07-07en_HK
patents.relation.familyUS 5863770 (A) 1999-01-26en_HK
patents.relation.familyUS 6063913 (A) 2000-05-16en_HK
patents.relation.familyUS 6201107 (B1) 2001-03-13en_HK
patents.relation.familyUS 6730777 (B1) 2004-05-04en_HK
patents.relation.familyUS 6902907 (B1) 2005-06-07en_HK
patents.relation.familyUS 6984487 (B1) 2006-01-10en_HK
patents.relation.familyWO 9102796 (A1) 1991-03-07en_HK
patents.relation.familyWO 9205252 (A1) 1992-04-02en_HK
patents.relation.familyWO 9205273 (A1) 1992-04-02en_HK
patents.relation.familyWO 9307265 (A1) 1993-04-15en_HK
patents.relation.familyWO 9317040 (A2) 1993-09-02en_HK
patents.relation.familyWO 9406283 (A1) 1994-03-31en_HK
patents.relation.familyWO 9428938 (A1) 1994-12-22en_HK
patents.description.kindAen_HK
patents.typePatent_granteden_HK

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