granted patent: Introns and exons of the cystic fibrosis gene and mutations thereof

TitleIntrons and exons of the cystic fibrosis gene and mutations thereof
Granted PatentUS 6001588
Granted Date1999-12-14
Priority Date1990-01-12 CA19902007699
1990-03-01 CA19902011253
1990-07-10 CA19902020817
1991-01-11 PCT/CA1991000009
Inventors
Issue Date1999
Citation
US Patent US 6001588. Washington, DC: US Patent and Trademark Office (USPTO), 1999 How to Cite?
AbstractPCT No. PCT/CA91/00009 Sec. 371 Date Jul. 13, 1992 Sec. 102(e) Date Jul. 13, 1992 PCT Filed Jan. 11, 1991 PCT Pub. No. WO91/10734 PCT Pub. Date Jul. 25, 1991The identification, isolation and cloning of DNA sequences coding for mutant forms of the cystic fibrosis gene and their gene product are described. DNA sequence information and information relating to the genomic structure of the cystic fibrosis gene are provided. The mutant forms of the CF gene include specific sequence alterations in coding portions or of other genetic information at exon/intron boundaries and altered RNA transcripts and mutant protein products. Such DNA and protein information is useful in developing DNA or protein diagnosis for CF mutations, carrier and patient screening, as well as cloning of mutant genes and manufacturing of their proteins for investigation into therapies for cystic fibrosis.
Persistent Identifierhttp://hdl.handle.net/10722/177028
References

 

DC FieldValueLanguage
dc.date.accessioned2012-11-30T08:38:58Z-
dc.date.available2012-11-30T08:38:58Z-
dc.date.issued1999-
dc.identifier.citationUS Patent US 6001588. Washington, DC: US Patent and Trademark Office (USPTO), 1999en_HK
dc.identifier.urihttp://hdl.handle.net/10722/177028-
dc.description.abstractPCT No. PCT/CA91/00009 Sec. 371 Date Jul. 13, 1992 Sec. 102(e) Date Jul. 13, 1992 PCT Filed Jan. 11, 1991 PCT Pub. No. WO91/10734 PCT Pub. Date Jul. 25, 1991The identification, isolation and cloning of DNA sequences coding for mutant forms of the cystic fibrosis gene and their gene product are described. DNA sequence information and information relating to the genomic structure of the cystic fibrosis gene are provided. The mutant forms of the CF gene include specific sequence alterations in coding portions or of other genetic information at exon/intron boundaries and altered RNA transcripts and mutant protein products. Such DNA and protein information is useful in developing DNA or protein diagnosis for CF mutations, carrier and patient screening, as well as cloning of mutant genes and manufacturing of their proteins for investigation into therapies for cystic fibrosis.en_HK
dc.relation.isreferencedbyUS 2003194699 (A1) 2003-10-16en_HK
dc.relation.isreferencedbyUS 6653078 (B2) 2003-11-25en_HK
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License For Public Patent Documentsen_US
dc.titleIntrons and exons of the cystic fibrosis gene and mutations thereofen_HK
dc.typePatenten_US
dc.description.naturepublished_or_final_versionen_US
dc.contributor.inventorTsui, LCen_HK
dc.contributor.inventorRommens, Johanna Men_HK
dc.contributor.inventorKerem, Bat-Shevaen_HK
patents.identifier.applicationUS 07/890609en_HK
patents.identifier.grantedUS 6001588en_HK
patents.description.assigneeHSC RES DEV CORP [CA]en_HK
patents.description.countryUnited States of Americaen_HK
patents.date.granted1999-12-14en_HK
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dc.relation.referencesGB 2203742 (A) 1988-10-26en_HK
dc.relation.referencesWO 9102796 (A1) 1991-03-07en_HK
patents.date.application1992-07-13en_HK
patents.date.priority1990-01-12 CA19902007699en_HK
patents.date.priority1990-03-01 CA19902011253en_HK
patents.date.priority1990-07-10 CA19902020817en_HK
patents.date.priority1991-01-11 PCT/CA1991000009en_HK
patents.description.ccUSen_HK
patents.relation.familyAU 7060591 (A) 1991-08-05en_HK
patents.relation.familyCA 2007699 (A1) 1991-07-12en_HK
patents.relation.familyCA 2011253 (A1) 1991-09-01en_HK
patents.relation.familyCA 2020817 (A1) 1992-01-11en_HK
patents.relation.familyCA 2073441 (A1) 1991-07-13en_HK
patents.relation.familyDE 69132616 (T2) 2002-02-21en_HK
patents.relation.familyEP 0667900 (A1) 1995-08-23en_HK
patents.relation.familyUS 5981178 (A) 1999-11-09en_HK
patents.relation.familyUS 6001588 (A) 1999-12-14en_HK
patents.relation.familyWO 9110734 (A1) 1991-07-25en_HK
patents.description.kindAen_HK
patents.typePatent_granteden_HK

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