published patent: PROTECTIVE AGENT FOR RETINAL NERVE OR OPTIC NERVE

TitlePROTECTIVE AGENT FOR RETINAL NERVE OR OPTIC NERVE
Priority Date2007-01-31 JP20070021852
2008-01-30 PCT/JP2008051338
Inventors
Issue Date2010
Citation
US Published patent application US 2010216856. Washington, DC: US Patent and Trademark Office (USPTO), 2010 How to Cite?
AbstractThe present invention provides a protective agent for retinal nerve or optic nerve which exerts its effect through a different mechanism from that of conventional therapeutic agents and can be taken for long periods. The present invention is the protective agent for retinal nerve or optic nerve which comprises a compound with aldose reductase inhibiting activity such as the compound represented by the following general formula as an active ingredient. A preferable compound thereof is (2S,4S)-6-fluoro-2',5'-dioxospiro[chroman-4,4'-imidazolidine]-2-carboxamide: wherein X represents a halogen atom or a hydrogen atom, R1 and R2 independently represent a hydrogen atom or an optionally substituted C1 to C6 alkyl group, or R1 and R2, together with a nitrogen atom bound thereto, or optionally another nitrogen atom or an oxygen atom, are combined to form a 5- to 6-membered heterocycle.
Persistent Identifierhttp://hdl.handle.net/10722/177001
References

 

DC FieldValueLanguage
dc.date.accessioned2012-11-30T08:38:55Z-
dc.date.available2012-11-30T08:38:55Z-
dc.date.issued2010-
dc.identifier.citationUS Published patent application US 2010216856. Washington, DC: US Patent and Trademark Office (USPTO), 2010en_HK
dc.identifier.urihttp://hdl.handle.net/10722/177001-
dc.description.abstractThe present invention provides a protective agent for retinal nerve or optic nerve which exerts its effect through a different mechanism from that of conventional therapeutic agents and can be taken for long periods. The present invention is the protective agent for retinal nerve or optic nerve which comprises a compound with aldose reductase inhibiting activity such as the compound represented by the following general formula as an active ingredient. A preferable compound thereof is (2S,4S)-6-fluoro-2',5'-dioxospiro[chroman-4,4'-imidazolidine]-2-carboxamide: wherein X represents a halogen atom or a hydrogen atom, R1 and R2 independently represent a hydrogen atom or an optionally substituted C1 to C6 alkyl group, or R1 and R2, together with a nitrogen atom bound thereto, or optionally another nitrogen atom or an oxygen atom, are combined to form a 5- to 6-membered heterocycle.en_HK
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License For Public Patent Documentsen_US
dc.titlePROTECTIVE AGENT FOR RETINAL NERVE OR OPTIC NERVEen_HK
dc.typePatenten_US
dc.description.naturepublished_or_final_versionen_US
dc.contributor.inventorChung, SKen_HK
dc.contributor.inventorChung, Stephenen_HK
dc.contributor.inventorHibi, Chihiroen_HK
patents.identifier.applicationUS 12/517882en_HK
patents.description.assigneeSANWA KAGAKU KENKYUSHO CO [JP]en_HK
patents.description.countryUnited States of Americaen_HK
patents.date.publication2010-08-26en_HK
dc.relation.referencesUS 4966452 (A) 1990-10-30en_HK
dc.relation.referencesUS 5212196 (A) 1993-05-18en_HK
dc.relation.referencesEP 0258476 (A1) 1988-03-09en_HK
dc.relation.referencesEP 0258476 (B1) 1990-04-25en_HK
patents.date.application2008-01-30en_HK
patents.date.priority2007-01-31 JP20070021852en_HK
patents.date.priority2008-01-30 PCT/JP2008051338en_HK
patents.description.ccUSen_HK
patents.identifier.publicationUS 2010216856en_HK
patents.relation.familyAU 2008210970 (A1) 2008-08-07en_HK
patents.relation.familyCA 2673751 (A1) 2008-08-07en_HK
patents.relation.familyCN 101594884 (A) 2009-12-02en_HK
patents.relation.familyEP 2110141 (A1) 2009-10-21en_HK
patents.relation.familyUS 2010216856 (A1) 2010-08-26en_HK
patents.relation.familyWO 2008093691 (A1) 2008-08-07en_HK
patents.description.kindA1en_HK
patents.typePatent_publisheden_HK

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