File Download
Patent History
- ApplicationUS 12/469319 2009-05-20
- PublicationUS 2009298797 2009-12-03
Patent Family
Supplementary
-
Citations:
- Appears in Collections:
published patent: COMBINATION THERAPY FOR THE TREATMENT OF INFLUENZA
Title | COMBINATION THERAPY FOR THE TREATMENT OF INFLUENZA |
---|---|
Priority Date | 2009-05-20 US 12/469319 2008-05-23 US 12/055573P |
Inventors | |
Issue Date | 2009 |
Citation | US Published patent application US 2009298797. Washington, DC: US Patent and Trademark Office (USPTO), 2009 How to Cite? |
Abstract | Compositions and methods for treating one or more symptoms of influenza, preferably influenza due to infection with influenza A (H5N1) are provided. It has been discovered that administration of a combination of a neuraminidase inhibitor with two immunomodulators increases survivability in subjects 24, 48, or even 72 hours post infection compared to administration of the neuraminidase inhibitor alone. A preferred neuraminidase inhibitor is zanamivir. Preferred immunomodulators include, but are not limited to celecoxib and mesalazine. Another embodiment provides a method for treating influenza, preferably, influenza due to infection with avian influenza A (H5N1) by administering to subject infected with the influenza virus, an effective amount of a neuraminidase inhibitor to inhibit or reduce budding of the influenza virus from infected cells of the subject, and an effective amount of at least two immunomodulators effective to reduce or inhibit one or more symptoms of inflammation in the subject. |
Persistent Identifier | http://hdl.handle.net/10722/176984 |
DC Field | Value | Language |
---|---|---|
dc.date.accessioned | 2012-11-30T08:38:53Z | - |
dc.date.available | 2012-11-30T08:38:53Z | - |
dc.date.issued | 2009 | - |
dc.identifier.citation | US Published patent application US 2009298797. Washington, DC: US Patent and Trademark Office (USPTO), 2009 | en_HK |
dc.identifier.uri | http://hdl.handle.net/10722/176984 | - |
dc.description.abstract | Compositions and methods for treating one or more symptoms of influenza, preferably influenza due to infection with influenza A (H5N1) are provided. It has been discovered that administration of a combination of a neuraminidase inhibitor with two immunomodulators increases survivability in subjects 24, 48, or even 72 hours post infection compared to administration of the neuraminidase inhibitor alone. A preferred neuraminidase inhibitor is zanamivir. Preferred immunomodulators include, but are not limited to celecoxib and mesalazine. Another embodiment provides a method for treating influenza, preferably, influenza due to infection with avian influenza A (H5N1) by administering to subject infected with the influenza virus, an effective amount of a neuraminidase inhibitor to inhibit or reduce budding of the influenza virus from infected cells of the subject, and an effective amount of at least two immunomodulators effective to reduce or inhibit one or more symptoms of inflammation in the subject. | en_HK |
dc.title | COMBINATION THERAPY FOR THE TREATMENT OF INFLUENZA | en_HK |
dc.type | Patent | en_US |
dc.description.nature | published_or_final_version | en_US |
dc.contributor.inventor | Zheng, B | en_HK |
dc.contributor.inventor | Yuen, KY | en_HK |
patents.identifier.application | US 12/469319 | en_HK |
patents.description.assignee | UNIV HONG KONG | en_HK |
patents.description.country | United States of America | en_HK |
patents.date.publication | 2009-12-03 | en_HK |
patents.identifier.hkutechid | Micro-2008-00283 | - |
patents.date.application | 2009-05-20 | en_HK |
patents.date.priority | 2009-05-20 US 12/469319 | en_HK |
patents.date.priority | 2008-05-23 US 12/055573P | en_HK |
patents.description.cc | US | en_HK |
patents.identifier.publication | US 2009298797 | en_HK |
patents.relation.family | CN 102036658 (A) 2011-04-27 | en_HK |
patents.relation.family | US 2009298797 (A1) 2009-12-03 | en_HK |
patents.relation.family | WO 2009140853 (A1) 2009-11-26 | en_HK |
patents.description.kind | A1 | en_HK |
patents.type | Patent_published | en_HK |