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Article: A randomized double blind comparison of real and placebo acupuncture in IVF treatment

TitleA randomized double blind comparison of real and placebo acupuncture in IVF treatment
Authors
Issue Date2009
Citation
Deutsche Zeitschrift Fur Akupunktur, 2009, v. 52 n. 1, p. 49-50 How to Cite?
AbstractBackground: Acupuncture has been used during IVF treatment as it may improve outcome, however, there are concerns about the true efficacy of this approach. This randomized double blind study aimed to compare real acupuncture with placebo acupuncture in patients undergoing IVF treatment. Methods: On the day of embryo transfer (ET), 370 patients were randomly allocated to either real or placebo acupuncture according to a computer-generated randomization list in sealed opaque envelopes. They received 25 min of real or placebo acupuncture before and after ET. The endometrial and subendometrial vascularity, serum cortisol concentration and the anxiety level were evaluated before and after real and placebo acupuncture. Results: The overall pregnancy rate was significantly higher in the placebo acupuncture group than that in the real acupuncture group (55.1 versus 43.8 %, respectively, P = 0.038; Common odds ratio 1.578 95 % confidence interval 1.047-2.378). No significant differences were found in rates of ongoing pregnancy and live birth between the two groups. Conclusions: Reduction of endometrial and subendometrial vascularity, serum cortisol concentration and the anxiety level were observed following both real and placebo acupuncture, although there were no significant differences in the changes in all these indices between the two groups. Placebo acupuncture was associated with a significantly higher overall pregnancy rate when compared with real acupuncture. Placebo acupuncture may not be inert.
Persistent Identifierhttp://hdl.handle.net/10722/173345
ISSN
2015 SCImago Journal Rankings: 0.193
References

 

DC FieldValueLanguage
dc.contributor.authorSo, EWSen_US
dc.contributor.authorNg, EHYen_US
dc.contributor.authorWong, YYen_US
dc.contributor.authorLau, EYLen_US
dc.contributor.authorYeung, WSBen_US
dc.contributor.authorHo, PCen_US
dc.contributor.authorIrnich, Den_US
dc.date.accessioned2012-10-30T06:29:31Z-
dc.date.available2012-10-30T06:29:31Z-
dc.date.issued2009en_US
dc.identifier.citationDeutsche Zeitschrift Fur Akupunktur, 2009, v. 52 n. 1, p. 49-50en_US
dc.identifier.issn0415-6412en_US
dc.identifier.urihttp://hdl.handle.net/10722/173345-
dc.description.abstractBackground: Acupuncture has been used during IVF treatment as it may improve outcome, however, there are concerns about the true efficacy of this approach. This randomized double blind study aimed to compare real acupuncture with placebo acupuncture in patients undergoing IVF treatment. Methods: On the day of embryo transfer (ET), 370 patients were randomly allocated to either real or placebo acupuncture according to a computer-generated randomization list in sealed opaque envelopes. They received 25 min of real or placebo acupuncture before and after ET. The endometrial and subendometrial vascularity, serum cortisol concentration and the anxiety level were evaluated before and after real and placebo acupuncture. Results: The overall pregnancy rate was significantly higher in the placebo acupuncture group than that in the real acupuncture group (55.1 versus 43.8 %, respectively, P = 0.038; Common odds ratio 1.578 95 % confidence interval 1.047-2.378). No significant differences were found in rates of ongoing pregnancy and live birth between the two groups. Conclusions: Reduction of endometrial and subendometrial vascularity, serum cortisol concentration and the anxiety level were observed following both real and placebo acupuncture, although there were no significant differences in the changes in all these indices between the two groups. Placebo acupuncture was associated with a significantly higher overall pregnancy rate when compared with real acupuncture. Placebo acupuncture may not be inert.en_US
dc.languageengen_US
dc.relation.ispartofDeutsche Zeitschrift fur Akupunkturen_US
dc.titleA randomized double blind comparison of real and placebo acupuncture in IVF treatmenten_US
dc.typeArticleen_US
dc.identifier.emailNg, EHY:nghye@hkucc.hku.hken_US
dc.identifier.emailYeung, WSB:wsbyeung@hkucc.hku.hken_US
dc.identifier.emailHo, PC:pcho@hku.hken_US
dc.identifier.authorityNg, EHY=rp00426en_US
dc.identifier.authorityYeung, WSB=rp00331en_US
dc.identifier.authorityHo, PC=rp00325en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1016/j.dza.2009.02.008en_US
dc.identifier.scopuseid_2-s2.0-64549115940en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-64549115940&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume52en_US
dc.identifier.issue1en_US
dc.identifier.spage49en_US
dc.identifier.epage50en_US
dc.identifier.scopusauthoridSo, EWS=20936214700en_US
dc.identifier.scopusauthoridNg, EHY=35238184300en_US
dc.identifier.scopusauthoridWong, YY=7403041699en_US
dc.identifier.scopusauthoridLau, EYL=7103086093en_US
dc.identifier.scopusauthoridYeung, WSB=7102370745en_US
dc.identifier.scopusauthoridHo, PC=7402211440en_US
dc.identifier.scopusauthoridIrnich, D=26642964600en_US

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