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- Publisher Website: 10.1093/humrep/deh163
- Scopus: eid_2-s2.0-1842639551
- PMID: 15016783
- WOS: WOS:000220486800023
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Article: Concentrations of endometrial protein PP 14 and CA-125 in uterine flushings performed in natural and stimulated cycles
Title | Concentrations of endometrial protein PP 14 and CA-125 in uterine flushings performed in natural and stimulated cycles |
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Authors | |
Keywords | CA-125 Excessive responders PP14 Uterine flushing |
Issue Date | 2004 |
Publisher | Oxford University Press. The Journal's web site is located at http://humrep.oxfordjournals.org/ |
Citation | Human Reproduction, 2004, v. 19 n. 4, p. 905-910 How to Cite? |
Abstract | Background: Impaired implantation in assisted reproduction cycles with high serum estradiol (E2) concentrations may be attributed to abnormal endometrial development. This study compared concentrations of endometrial proteins in uterine flushings of infertile patients between natural and stimulated cycles. Methods: Patients received a standard regimen of ovarian stimulation. Seven days after the LH surge in natural cycles or the hCG injection in stimulated cycles, uterine flushings were performed by slowly injecting and aspirating normal saline through a paediatric Foley catheter. Natural cycles were considered as group A whereas stimulated cycles with serum E2 <20 000 pmol/l and serum E2 >20 000 pmol/l were classified as groups B and C respectively. PP 14 and CA-125 in uterine flushings were measured and expressed per total protein content. Results: Concentrations of the total protein, PP 14 and CA-125 in the uterine flushings were similar among the three groups. PP 14 per total protein in the uterine flushings was significantly correlated with serum E2 on the day of hCG (r = 0.459; P = 0.009) in natural cycles only but not in stimulated cycles. Conclusion: There was no significant difference between natural and stimulated cycles in concentrations of PP 14 and CA-125 in uterine flushings performed in the mid-luteal phase. © European Society of Human Reproduction and Embryology 2004; all rights reserved. |
Persistent Identifier | http://hdl.handle.net/10722/173284 |
ISSN | 2023 Impact Factor: 6.0 2023 SCImago Journal Rankings: 1.852 |
ISI Accession Number ID | |
References |
DC Field | Value | Language |
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dc.contributor.author | Ng, EHY | en_US |
dc.contributor.author | Laird, SM | en_US |
dc.contributor.author | Li, TC | en_US |
dc.contributor.author | Yeung, WSB | en_US |
dc.contributor.author | Ho, PC | en_US |
dc.date.accessioned | 2012-10-30T06:29:04Z | - |
dc.date.available | 2012-10-30T06:29:04Z | - |
dc.date.issued | 2004 | en_US |
dc.identifier.citation | Human Reproduction, 2004, v. 19 n. 4, p. 905-910 | en_US |
dc.identifier.issn | 0268-1161 | en_US |
dc.identifier.uri | http://hdl.handle.net/10722/173284 | - |
dc.description.abstract | Background: Impaired implantation in assisted reproduction cycles with high serum estradiol (E2) concentrations may be attributed to abnormal endometrial development. This study compared concentrations of endometrial proteins in uterine flushings of infertile patients between natural and stimulated cycles. Methods: Patients received a standard regimen of ovarian stimulation. Seven days after the LH surge in natural cycles or the hCG injection in stimulated cycles, uterine flushings were performed by slowly injecting and aspirating normal saline through a paediatric Foley catheter. Natural cycles were considered as group A whereas stimulated cycles with serum E2 <20 000 pmol/l and serum E2 >20 000 pmol/l were classified as groups B and C respectively. PP 14 and CA-125 in uterine flushings were measured and expressed per total protein content. Results: Concentrations of the total protein, PP 14 and CA-125 in the uterine flushings were similar among the three groups. PP 14 per total protein in the uterine flushings was significantly correlated with serum E2 on the day of hCG (r = 0.459; P = 0.009) in natural cycles only but not in stimulated cycles. Conclusion: There was no significant difference between natural and stimulated cycles in concentrations of PP 14 and CA-125 in uterine flushings performed in the mid-luteal phase. © European Society of Human Reproduction and Embryology 2004; all rights reserved. | en_US |
dc.language | eng | en_US |
dc.publisher | Oxford University Press. The Journal's web site is located at http://humrep.oxfordjournals.org/ | en_US |
dc.relation.ispartof | Human Reproduction | en_US |
dc.rights | Human Reproduction. Copyright © Oxford University Press. | - |
dc.subject | CA-125 | - |
dc.subject | Excessive responders | - |
dc.subject | PP14 | - |
dc.subject | Uterine flushing | - |
dc.subject.mesh | Adult | en_US |
dc.subject.mesh | Ca-125 Antigen - Metabolism | en_US |
dc.subject.mesh | Chorionic Gonadotropin - Administration & Dosage - Therapeutic Use | en_US |
dc.subject.mesh | Endometrium - Metabolism | en_US |
dc.subject.mesh | Estradiol - Blood | en_US |
dc.subject.mesh | Female | en_US |
dc.subject.mesh | Glycoproteins - Metabolism | en_US |
dc.subject.mesh | Humans | en_US |
dc.subject.mesh | Infertility - Drug Therapy - Metabolism | en_US |
dc.subject.mesh | Injections, Intramuscular | en_US |
dc.subject.mesh | Luteal Phase | en_US |
dc.subject.mesh | Osmolar Concentration | en_US |
dc.subject.mesh | Ovulation Induction | en_US |
dc.subject.mesh | Pregnancy Proteins - Metabolism | en_US |
dc.subject.mesh | Therapeutic Irrigation | en_US |
dc.title | Concentrations of endometrial protein PP 14 and CA-125 in uterine flushings performed in natural and stimulated cycles | en_US |
dc.type | Article | en_US |
dc.identifier.email | Ng, EHY:nghye@hkucc.hku.hk | en_US |
dc.identifier.email | Yeung, WSB:wsbyeung@hkucc.hku.hk | en_US |
dc.identifier.email | Ho, PC:pcho@hku.hk | en_US |
dc.identifier.authority | Ng, EHY=rp00426 | en_US |
dc.identifier.authority | Yeung, WSB=rp00331 | en_US |
dc.identifier.authority | Ho, PC=rp00325 | en_US |
dc.description.nature | link_to_subscribed_fulltext | en_US |
dc.identifier.doi | 10.1093/humrep/deh163 | en_US |
dc.identifier.pmid | 15016783 | - |
dc.identifier.scopus | eid_2-s2.0-1842639551 | en_US |
dc.identifier.hkuros | 87437 | - |
dc.relation.references | http://www.scopus.com/mlt/select.url?eid=2-s2.0-1842639551&selection=ref&src=s&origin=recordpage | en_US |
dc.identifier.volume | 19 | en_US |
dc.identifier.issue | 4 | en_US |
dc.identifier.spage | 905 | en_US |
dc.identifier.epage | 910 | en_US |
dc.identifier.isi | WOS:000220486800023 | - |
dc.publisher.place | United Kingdom | en_US |
dc.identifier.scopusauthorid | Ng, EHY=35238184300 | en_US |
dc.identifier.scopusauthorid | Laird, SM=7005020725 | en_US |
dc.identifier.scopusauthorid | Li, TC=7406374412 | en_US |
dc.identifier.scopusauthorid | Yeung, WSB=7102370745 | en_US |
dc.identifier.scopusauthorid | Ho, PC=7402211440 | en_US |
dc.identifier.issnl | 0268-1161 | - |