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Article: Concentrations of endometrial protein PP 14 and CA-125 in uterine flushings performed in natural and stimulated cycles

TitleConcentrations of endometrial protein PP 14 and CA-125 in uterine flushings performed in natural and stimulated cycles
Authors
Issue Date2004
PublisherOxford University Press. The Journal's web site is located at http://humrep.oxfordjournals.org/
Citation
Human Reproduction, 2004, v. 19 n. 4, p. 905-910 How to Cite?
AbstractBackground: Impaired implantation in assisted reproduction cycles with high serum estradiol (E2) concentrations may be attributed to abnormal endometrial development. This study compared concentrations of endometrial proteins in uterine flushings of infertile patients between natural and stimulated cycles. Methods: Patients received a standard regimen of ovarian stimulation. Seven days after the LH surge in natural cycles or the hCG injection in stimulated cycles, uterine flushings were performed by slowly injecting and aspirating normal saline through a paediatric Foley catheter. Natural cycles were considered as group A whereas stimulated cycles with serum E2 <20 000 pmol/l and serum E2 >20 000 pmol/l were classified as groups B and C respectively. PP 14 and CA-125 in uterine flushings were measured and expressed per total protein content. Results: Concentrations of the total protein, PP 14 and CA-125 in the uterine flushings were similar among the three groups. PP 14 per total protein in the uterine flushings was significantly correlated with serum E2 on the day of hCG (r = 0.459; P = 0.009) in natural cycles only but not in stimulated cycles. Conclusion: There was no significant difference between natural and stimulated cycles in concentrations of PP 14 and CA-125 in uterine flushings performed in the mid-luteal phase. © European Society of Human Reproduction and Embryology 2004; all rights reserved.
Persistent Identifierhttp://hdl.handle.net/10722/173284
ISSN
2015 Impact Factor: 4.621
2015 SCImago Journal Rankings: 2.271
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorNg, EHYen_US
dc.contributor.authorLaird, SMen_US
dc.contributor.authorLi, TCen_US
dc.contributor.authorYeung, WSBen_US
dc.contributor.authorHo, PCen_US
dc.date.accessioned2012-10-30T06:29:04Z-
dc.date.available2012-10-30T06:29:04Z-
dc.date.issued2004en_US
dc.identifier.citationHuman Reproduction, 2004, v. 19 n. 4, p. 905-910en_US
dc.identifier.issn0268-1161en_US
dc.identifier.urihttp://hdl.handle.net/10722/173284-
dc.description.abstractBackground: Impaired implantation in assisted reproduction cycles with high serum estradiol (E2) concentrations may be attributed to abnormal endometrial development. This study compared concentrations of endometrial proteins in uterine flushings of infertile patients between natural and stimulated cycles. Methods: Patients received a standard regimen of ovarian stimulation. Seven days after the LH surge in natural cycles or the hCG injection in stimulated cycles, uterine flushings were performed by slowly injecting and aspirating normal saline through a paediatric Foley catheter. Natural cycles were considered as group A whereas stimulated cycles with serum E2 <20 000 pmol/l and serum E2 >20 000 pmol/l were classified as groups B and C respectively. PP 14 and CA-125 in uterine flushings were measured and expressed per total protein content. Results: Concentrations of the total protein, PP 14 and CA-125 in the uterine flushings were similar among the three groups. PP 14 per total protein in the uterine flushings was significantly correlated with serum E2 on the day of hCG (r = 0.459; P = 0.009) in natural cycles only but not in stimulated cycles. Conclusion: There was no significant difference between natural and stimulated cycles in concentrations of PP 14 and CA-125 in uterine flushings performed in the mid-luteal phase. © European Society of Human Reproduction and Embryology 2004; all rights reserved.en_US
dc.languageengen_US
dc.publisherOxford University Press. The Journal's web site is located at http://humrep.oxfordjournals.org/en_US
dc.relation.ispartofHuman Reproductionen_US
dc.rightsHuman Reproduction. Copyright © Oxford University Press.-
dc.subject.meshAdulten_US
dc.subject.meshCa-125 Antigen - Metabolismen_US
dc.subject.meshChorionic Gonadotropin - Administration & Dosage - Therapeutic Useen_US
dc.subject.meshEndometrium - Metabolismen_US
dc.subject.meshEstradiol - Blooden_US
dc.subject.meshFemaleen_US
dc.subject.meshGlycoproteins - Metabolismen_US
dc.subject.meshHumansen_US
dc.subject.meshInfertility - Drug Therapy - Metabolismen_US
dc.subject.meshInjections, Intramuscularen_US
dc.subject.meshLuteal Phaseen_US
dc.subject.meshOsmolar Concentrationen_US
dc.subject.meshOvulation Inductionen_US
dc.subject.meshPregnancy Proteins - Metabolismen_US
dc.subject.meshTherapeutic Irrigationen_US
dc.titleConcentrations of endometrial protein PP 14 and CA-125 in uterine flushings performed in natural and stimulated cyclesen_US
dc.typeArticleen_US
dc.identifier.emailNg, EHY:nghye@hkucc.hku.hken_US
dc.identifier.emailYeung, WSB:wsbyeung@hkucc.hku.hken_US
dc.identifier.emailHo, PC:pcho@hku.hken_US
dc.identifier.authorityNg, EHY=rp00426en_US
dc.identifier.authorityYeung, WSB=rp00331en_US
dc.identifier.authorityHo, PC=rp00325en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1093/humrep/deh163en_US
dc.identifier.pmid15016783-
dc.identifier.scopuseid_2-s2.0-1842639551en_US
dc.identifier.hkuros87437-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-1842639551&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume19en_US
dc.identifier.issue4en_US
dc.identifier.spage905en_US
dc.identifier.epage910en_US
dc.identifier.isiWOS:000220486800023-
dc.publisher.placeUnited Kingdomen_US
dc.identifier.scopusauthoridNg, EHY=35238184300en_US
dc.identifier.scopusauthoridLaird, SM=7005020725en_US
dc.identifier.scopusauthoridLi, TC=7406374412en_US
dc.identifier.scopusauthoridYeung, WSB=7102370745en_US
dc.identifier.scopusauthoridHo, PC=7402211440en_US

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