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Article: Cancer of the cervix stage Ib and IIa: Survival related to treatment and histopathological risk factors

TitleCancer of the cervix stage Ib and IIa: Survival related to treatment and histopathological risk factors
Authors
Issue Date1988
PublisherWB Saunders Co Ltd. The Journal's web site is located at http://www.elsevier.com/locate/ejso
Citation
European Journal Of Surgical Oncology, 1988, v. 14 n. 3, p. 203-208 How to Cite?
AbstractForty-five patients with carcinoma of the cervix stage Ib or IIa underwent primary radical surgery. The patho-histological examination of the surgical specimens showed, that pelvic lymph node metastases, tumour volume, depth of tumour invasion, lymphatic or vascular permeation and parametrial involvement were significant bad prognostic factors. The histological types of squamous cell carcinomas and local lympho-plasmocytic stromal reaction to the tumour had no statistical prognostic significance. A simple and objective method of assessing tumour volume is described. The 5-year actuarial survival rate for patients with metastatic pelvic lymph nodes (33% of the patients in this study) treated by surgery and additional postoperative external whole pelvis radiotherapy was 55%. This is significantly lower than the 86% 5-year actuarial surivival rate of patients without pelvic lymph node metastases treated by surgery alone (P < 0.05). The postoperative radiotherapy of carcinoma of the cervix with bad prognostic factors including pelvic lymph node metastases seems to improve local tumour control and perhaps survival in a subgroup of node negative tumours presenting other histopathological risk factors.
Persistent Identifierhttp://hdl.handle.net/10722/173133
ISSN
2015 Impact Factor: 2.94
2015 SCImago Journal Rankings: 1.327
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorNgan, HYSen_US
dc.contributor.authorObradovic, Den_US
dc.contributor.authorKrauer, Fen_US
dc.date.accessioned2012-10-30T06:28:07Z-
dc.date.available2012-10-30T06:28:07Z-
dc.date.issued1988en_US
dc.identifier.citationEuropean Journal Of Surgical Oncology, 1988, v. 14 n. 3, p. 203-208en_US
dc.identifier.issn0748-7983en_US
dc.identifier.urihttp://hdl.handle.net/10722/173133-
dc.description.abstractForty-five patients with carcinoma of the cervix stage Ib or IIa underwent primary radical surgery. The patho-histological examination of the surgical specimens showed, that pelvic lymph node metastases, tumour volume, depth of tumour invasion, lymphatic or vascular permeation and parametrial involvement were significant bad prognostic factors. The histological types of squamous cell carcinomas and local lympho-plasmocytic stromal reaction to the tumour had no statistical prognostic significance. A simple and objective method of assessing tumour volume is described. The 5-year actuarial survival rate for patients with metastatic pelvic lymph nodes (33% of the patients in this study) treated by surgery and additional postoperative external whole pelvis radiotherapy was 55%. This is significantly lower than the 86% 5-year actuarial surivival rate of patients without pelvic lymph node metastases treated by surgery alone (P < 0.05). The postoperative radiotherapy of carcinoma of the cervix with bad prognostic factors including pelvic lymph node metastases seems to improve local tumour control and perhaps survival in a subgroup of node negative tumours presenting other histopathological risk factors.en_US
dc.languageengen_US
dc.publisherWB Saunders Co Ltd. The Journal's web site is located at http://www.elsevier.com/locate/ejsoen_US
dc.relation.ispartofEuropean Journal of Surgical Oncologyen_US
dc.subject.meshAdulten_US
dc.subject.meshAgeden_US
dc.subject.meshCombined Modality Therapyen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshLymphatic Metastasisen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshNeoplasm Stagingen_US
dc.subject.meshPrognosisen_US
dc.subject.meshRisk Factorsen_US
dc.subject.meshUterine Cervical Neoplasms - Mortality - Pathology - Therapyen_US
dc.titleCancer of the cervix stage Ib and IIa: Survival related to treatment and histopathological risk factorsen_US
dc.typeArticleen_US
dc.identifier.emailNgan, HYS:hysngan@hkucc.hku.hken_US
dc.identifier.authorityNgan, HYS=rp00346en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.pmid3371471-
dc.identifier.scopuseid_2-s2.0-0023914356en_US
dc.identifier.volume14en_US
dc.identifier.issue3en_US
dc.identifier.spage203en_US
dc.identifier.epage208en_US
dc.identifier.isiWOS:A1988N887400002-
dc.publisher.placeUnited Kingdomen_US
dc.identifier.scopusauthoridNgan, HYS=34571944100en_US
dc.identifier.scopusauthoridObradovic, D=7005065269en_US
dc.identifier.scopusauthoridKrauer, F=7004223818en_US

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