File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)
Supplementary

Article: Left ventricular noncompaction in children

TitleLeft ventricular noncompaction in children
Authors
Issue Date2009
PublisherBlackwell Publishing, Inc. The Journal's web site is located at http://www.blackwellpublishing.com/chd
Citation
Congenital Heart Disease, 2009, v. 4 n. 4, p. 288-294 How to Cite?
AbstractObjective. Left ventricular noncompaction (LVNC) is an uncommon type of cardiomyopathy in children. We sought to determine the clinical presentations and outcomes of children diagnosed to have LVNC. Design. The case records of children diagnosed to have LVNC between 1999 and 2007 were reviewed. The diagnosis was based on echocardiographic finding of a thick noncompacted myocardium layer characterized by a trabecular meshwork with deep endomyocardial spaces. Results. Ten patients (seven males) were diagnosed to have LVNC at a median age of 2 years (range, 7 days to 12 years). Seven patients had isolated LVNC while three had associated structural congenital heart diseases. The right ventricle was also involved in two patients. Clinical presentations included congestive heart failure in eight patients, asymptomatic heart murmur in one, and syncope with exercise intolerance in one. At presentation, cardiomegaly was found in nine patients, electrocardiographic abnormalities in nine, and impaired LV contraction in six. Eight patients received anti-heart failure medications. Three patients died at a median of 1.5 years after diagnosis, two died suddenly of unknown causes, and one of heart failure. The seven surviving patients were followed up for a median of 2 years (range, 2 months to 3 years). Three patients developed cardiac arrhythmias. The LV function improved in three patients and worsened in one on follow-up. None of the patients developed thromboembolic complications. Conclusions. Left ventricular noncompaction in children is a heterogeneous condition. Long-term follow-up for development of progressive LV dysfunction and cardiac arrhythmias is indicated. © 2009 Copyright the Authors Journal compilation © 2009 Wiley Periodicals, Inc.
Persistent Identifierhttp://hdl.handle.net/10722/170419
ISSN
2015 Impact Factor: 1.21
2015 SCImago Journal Rankings: 0.695
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorKoh, Cen_US
dc.contributor.authorLee, PWen_US
dc.contributor.authorYung, TCen_US
dc.contributor.authorLun, KSen_US
dc.contributor.authorCheung, YFen_US
dc.date.accessioned2012-10-30T06:08:24Z-
dc.date.available2012-10-30T06:08:24Z-
dc.date.issued2009en_US
dc.identifier.citationCongenital Heart Disease, 2009, v. 4 n. 4, p. 288-294en_US
dc.identifier.issn1747-079Xen_US
dc.identifier.urihttp://hdl.handle.net/10722/170419-
dc.description.abstractObjective. Left ventricular noncompaction (LVNC) is an uncommon type of cardiomyopathy in children. We sought to determine the clinical presentations and outcomes of children diagnosed to have LVNC. Design. The case records of children diagnosed to have LVNC between 1999 and 2007 were reviewed. The diagnosis was based on echocardiographic finding of a thick noncompacted myocardium layer characterized by a trabecular meshwork with deep endomyocardial spaces. Results. Ten patients (seven males) were diagnosed to have LVNC at a median age of 2 years (range, 7 days to 12 years). Seven patients had isolated LVNC while three had associated structural congenital heart diseases. The right ventricle was also involved in two patients. Clinical presentations included congestive heart failure in eight patients, asymptomatic heart murmur in one, and syncope with exercise intolerance in one. At presentation, cardiomegaly was found in nine patients, electrocardiographic abnormalities in nine, and impaired LV contraction in six. Eight patients received anti-heart failure medications. Three patients died at a median of 1.5 years after diagnosis, two died suddenly of unknown causes, and one of heart failure. The seven surviving patients were followed up for a median of 2 years (range, 2 months to 3 years). Three patients developed cardiac arrhythmias. The LV function improved in three patients and worsened in one on follow-up. None of the patients developed thromboembolic complications. Conclusions. Left ventricular noncompaction in children is a heterogeneous condition. Long-term follow-up for development of progressive LV dysfunction and cardiac arrhythmias is indicated. © 2009 Copyright the Authors Journal compilation © 2009 Wiley Periodicals, Inc.en_US
dc.languageengen_US
dc.publisherBlackwell Publishing, Inc. The Journal's web site is located at http://www.blackwellpublishing.com/chden_US
dc.relation.ispartofCongenital Heart Diseaseen_US
dc.subject.meshCardiomyopathies - Therapy - Ultrasonographyen_US
dc.subject.meshChilden_US
dc.subject.meshChild, Preschoolen_US
dc.subject.meshFatal Outcomeen_US
dc.subject.meshFemaleen_US
dc.subject.meshHeart Defects, Congenital - Therapy - Ultrasonographyen_US
dc.subject.meshHeart Failure - Therapy - Ultrasonographyen_US
dc.subject.meshHumansen_US
dc.subject.meshInfanten_US
dc.subject.meshInfant, Newbornen_US
dc.subject.meshMaleen_US
dc.subject.meshRetrospective Studiesen_US
dc.subject.meshVentricular Dysfunction, Left - Therapy - Ultrasonographyen_US
dc.titleLeft ventricular noncompaction in childrenen_US
dc.typeArticleen_US
dc.identifier.emailLee, PW:ppwlee@hku.hken_US
dc.identifier.emailCheung, YF:xfcheung@hku.hken_US
dc.identifier.authorityLee, PW=rp00462en_US
dc.identifier.authorityCheung, YF=rp00382en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1111/j.1747-0803.2009.00269.xen_US
dc.identifier.pmid19664035-
dc.identifier.scopuseid_2-s2.0-68349090331en_US
dc.identifier.hkuros160073-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-68349090331&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume4en_US
dc.identifier.issue4en_US
dc.identifier.spage288en_US
dc.identifier.epage294en_US
dc.identifier.isiWOS:000207893700014-
dc.publisher.placeUnited Statesen_US
dc.identifier.scopusauthoridKoh, C=26321638500en_US
dc.identifier.scopusauthoridLee, PW=14048822200en_US
dc.identifier.scopusauthoridYung, TC=9132842300en_US
dc.identifier.scopusauthoridLun, KS=8363663600en_US
dc.identifier.scopusauthoridCheung, YF=7202111067en_US
dc.identifier.citeulike5490354-

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats