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Article: Cardiovascular symptoms and signs in evaluating cardiac murmurs in children
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TitleCardiovascular symptoms and signs in evaluating cardiac murmurs in children
 
AuthorsKoo, S1
Yung, TC1
Lun, KS1
Chau, AKT1
Cheung, YF1
 
Issue Date2008
 
PublisherWiley-Blackwell Publishing Asia. The Journal's web site is located at http://www.blackwellpublishing.com/journals/PED
 
CitationPediatrics International, 2008, v. 50 n. 2, p. 145-149 [How to Cite?]
DOI: http://dx.doi.org/10.1111/j.1442-200X.2008.02560.x
 
AbstractBackground: The aim of the present study was to determine the usefulness of cardiovascular symptoms and signs in the recognition of significant congenital heart lesions that required surgical or catheter interventions in different pediatric age groups. Methods: A retrospective chart review was carried out of 110 patients with significant heart anomalies that required surgical or catheter interventions (group I) and 113 children, presenting with cardiac murmurs, with congenital heart conditions not requiring any interventions. (group II) Results: Clinical symptoms or signs were significantly more common in group I than in group II subjects (85% vs 32%, P < 0.0001). The odds of having significant lesions requiring interventions in the presence of either cardiovascular symptoms or signs were 37.5 (95% confidence interval [CI]: 6.5-218.1) for neonates, 14.5 (95%CI: 4.7-51.7) for infants, and 8.0 (95%CI: 3.3-19.2) for children and adolescents. In neonates, the negative predictive values of the absence of symptoms or signs in isolation were relatively low at 64% and 65%, respectively. In children beyond infancy, the positive predictive values of the presence of symptoms or signs in isolation were also low at 62% and 68%, respectively. Conclusions: Clinical assessment of cardiovascular symptoms and signs remains useful in the evaluation of the significance of pathological cardiac murmurs in children in the present era of technology. Nonetheless, the predictive values vary with different pediatric age groups. © 2008 Japan Pediatric Society.
 
ISSN1328-8067
2013 Impact Factor: 0.731
 
DOIhttp://dx.doi.org/10.1111/j.1442-200X.2008.02560.x
 
ISI Accession Number IDWOS:000254054800001
 
ReferencesReferences in Scopus
 
DC FieldValue
dc.contributor.authorKoo, S
 
dc.contributor.authorYung, TC
 
dc.contributor.authorLun, KS
 
dc.contributor.authorChau, AKT
 
dc.contributor.authorCheung, YF
 
dc.date.accessioned2012-10-30T06:07:59Z
 
dc.date.available2012-10-30T06:07:59Z
 
dc.date.issued2008
 
dc.description.abstractBackground: The aim of the present study was to determine the usefulness of cardiovascular symptoms and signs in the recognition of significant congenital heart lesions that required surgical or catheter interventions in different pediatric age groups. Methods: A retrospective chart review was carried out of 110 patients with significant heart anomalies that required surgical or catheter interventions (group I) and 113 children, presenting with cardiac murmurs, with congenital heart conditions not requiring any interventions. (group II) Results: Clinical symptoms or signs were significantly more common in group I than in group II subjects (85% vs 32%, P < 0.0001). The odds of having significant lesions requiring interventions in the presence of either cardiovascular symptoms or signs were 37.5 (95% confidence interval [CI]: 6.5-218.1) for neonates, 14.5 (95%CI: 4.7-51.7) for infants, and 8.0 (95%CI: 3.3-19.2) for children and adolescents. In neonates, the negative predictive values of the absence of symptoms or signs in isolation were relatively low at 64% and 65%, respectively. In children beyond infancy, the positive predictive values of the presence of symptoms or signs in isolation were also low at 62% and 68%, respectively. Conclusions: Clinical assessment of cardiovascular symptoms and signs remains useful in the evaluation of the significance of pathological cardiac murmurs in children in the present era of technology. Nonetheless, the predictive values vary with different pediatric age groups. © 2008 Japan Pediatric Society.
 
dc.description.naturelink_to_subscribed_fulltext
 
dc.identifier.citationPediatrics International, 2008, v. 50 n. 2, p. 145-149 [How to Cite?]
DOI: http://dx.doi.org/10.1111/j.1442-200X.2008.02560.x
 
dc.identifier.doihttp://dx.doi.org/10.1111/j.1442-200X.2008.02560.x
 
dc.identifier.epage149
 
dc.identifier.isiWOS:000254054800001
 
dc.identifier.issn1328-8067
2013 Impact Factor: 0.731
 
dc.identifier.issue2
 
dc.identifier.pmid18353047
 
dc.identifier.scopuseid_2-s2.0-40949121106
 
dc.identifier.spage145
 
dc.identifier.urihttp://hdl.handle.net/10722/170393
 
dc.identifier.volume50
 
dc.languageeng
 
dc.publisherWiley-Blackwell Publishing Asia. The Journal's web site is located at http://www.blackwellpublishing.com/journals/PED
 
dc.publisher.placeAustralia
 
dc.relation.ispartofPediatrics International
 
dc.relation.referencesReferences in Scopus
 
dc.subject.meshAdolescent
 
dc.subject.meshCardiovascular Diseases - Complications
 
dc.subject.meshChild
 
dc.subject.meshChild, Preschool
 
dc.subject.meshCohort Studies
 
dc.subject.meshFemale
 
dc.subject.meshHeart Defects, Congenital - Complications - Diagnosis - Surgery
 
dc.subject.meshHeart Murmurs - Etiology
 
dc.subject.meshHumans
 
dc.subject.meshInfant
 
dc.subject.meshMale
 
dc.subject.meshPredictive Value Of Tests
 
dc.subject.meshRetrospective Studies
 
dc.titleCardiovascular symptoms and signs in evaluating cardiac murmurs in children
 
dc.typeArticle
 
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<description.abstract>Background: The aim of the present study was to determine the usefulness of cardiovascular symptoms and signs in the recognition of significant congenital heart lesions that required surgical or catheter interventions in different pediatric age groups. Methods: A retrospective chart review was carried out of 110 patients with significant heart anomalies that required surgical or catheter interventions (group I) and 113 children, presenting with cardiac murmurs, with congenital heart conditions not requiring any interventions. (group II) Results: Clinical symptoms or signs were significantly more common in group I than in group II subjects (85% vs 32%, P &lt; 0.0001). The odds of having significant lesions requiring interventions in the presence of either cardiovascular symptoms or signs were 37.5 (95% confidence interval [CI]: 6.5-218.1) for neonates, 14.5 (95%CI: 4.7-51.7) for infants, and 8.0 (95%CI: 3.3-19.2) for children and adolescents. In neonates, the negative predictive values of the absence of symptoms or signs in isolation were relatively low at 64% and 65%, respectively. In children beyond infancy, the positive predictive values of the presence of symptoms or signs in isolation were also low at 62% and 68%, respectively. Conclusions: Clinical assessment of cardiovascular symptoms and signs remains useful in the evaluation of the significance of pathological cardiac murmurs in children in the present era of technology. Nonetheless, the predictive values vary with different pediatric age groups. &#169; 2008 Japan Pediatric Society.</description.abstract>
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Author Affiliations
  1. The University of Hong Kong