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Article: Cardiovascular symptoms and signs in evaluating cardiac murmurs in children

TitleCardiovascular symptoms and signs in evaluating cardiac murmurs in children
Authors
Issue Date2008
PublisherWiley-Blackwell Publishing Asia. The Journal's web site is located at http://www.blackwellpublishing.com/journals/PED
Citation
Pediatrics International, 2008, v. 50 n. 2, p. 145-149 How to Cite?
Abstract
Background: The aim of the present study was to determine the usefulness of cardiovascular symptoms and signs in the recognition of significant congenital heart lesions that required surgical or catheter interventions in different pediatric age groups. Methods: A retrospective chart review was carried out of 110 patients with significant heart anomalies that required surgical or catheter interventions (group I) and 113 children, presenting with cardiac murmurs, with congenital heart conditions not requiring any interventions. (group II) Results: Clinical symptoms or signs were significantly more common in group I than in group II subjects (85% vs 32%, P < 0.0001). The odds of having significant lesions requiring interventions in the presence of either cardiovascular symptoms or signs were 37.5 (95% confidence interval [CI]: 6.5-218.1) for neonates, 14.5 (95%CI: 4.7-51.7) for infants, and 8.0 (95%CI: 3.3-19.2) for children and adolescents. In neonates, the negative predictive values of the absence of symptoms or signs in isolation were relatively low at 64% and 65%, respectively. In children beyond infancy, the positive predictive values of the presence of symptoms or signs in isolation were also low at 62% and 68%, respectively. Conclusions: Clinical assessment of cardiovascular symptoms and signs remains useful in the evaluation of the significance of pathological cardiac murmurs in children in the present era of technology. Nonetheless, the predictive values vary with different pediatric age groups. © 2008 Japan Pediatric Society.
Persistent Identifierhttp://hdl.handle.net/10722/170393
ISSN
2013 Impact Factor: 0.731
ISI Accession Number ID
References

 

Author Affiliations
  1. The University of Hong Kong
DC FieldValueLanguage
dc.contributor.authorKoo, Sen_US
dc.contributor.authorYung, TCen_US
dc.contributor.authorLun, KSen_US
dc.contributor.authorChau, AKTen_US
dc.contributor.authorCheung, YFen_US
dc.date.accessioned2012-10-30T06:07:59Z-
dc.date.available2012-10-30T06:07:59Z-
dc.date.issued2008en_US
dc.identifier.citationPediatrics International, 2008, v. 50 n. 2, p. 145-149en_US
dc.identifier.issn1328-8067en_US
dc.identifier.urihttp://hdl.handle.net/10722/170393-
dc.description.abstractBackground: The aim of the present study was to determine the usefulness of cardiovascular symptoms and signs in the recognition of significant congenital heart lesions that required surgical or catheter interventions in different pediatric age groups. Methods: A retrospective chart review was carried out of 110 patients with significant heart anomalies that required surgical or catheter interventions (group I) and 113 children, presenting with cardiac murmurs, with congenital heart conditions not requiring any interventions. (group II) Results: Clinical symptoms or signs were significantly more common in group I than in group II subjects (85% vs 32%, P < 0.0001). The odds of having significant lesions requiring interventions in the presence of either cardiovascular symptoms or signs were 37.5 (95% confidence interval [CI]: 6.5-218.1) for neonates, 14.5 (95%CI: 4.7-51.7) for infants, and 8.0 (95%CI: 3.3-19.2) for children and adolescents. In neonates, the negative predictive values of the absence of symptoms or signs in isolation were relatively low at 64% and 65%, respectively. In children beyond infancy, the positive predictive values of the presence of symptoms or signs in isolation were also low at 62% and 68%, respectively. Conclusions: Clinical assessment of cardiovascular symptoms and signs remains useful in the evaluation of the significance of pathological cardiac murmurs in children in the present era of technology. Nonetheless, the predictive values vary with different pediatric age groups. © 2008 Japan Pediatric Society.en_US
dc.languageengen_US
dc.publisherWiley-Blackwell Publishing Asia. The Journal's web site is located at http://www.blackwellpublishing.com/journals/PEDen_US
dc.relation.ispartofPediatrics Internationalen_US
dc.subject.meshAdolescenten_US
dc.subject.meshCardiovascular Diseases - Complicationsen_US
dc.subject.meshChilden_US
dc.subject.meshChild, Preschoolen_US
dc.subject.meshCohort Studiesen_US
dc.subject.meshFemaleen_US
dc.subject.meshHeart Defects, Congenital - Complications - Diagnosis - Surgeryen_US
dc.subject.meshHeart Murmurs - Etiologyen_US
dc.subject.meshHumansen_US
dc.subject.meshInfanten_US
dc.subject.meshMaleen_US
dc.subject.meshPredictive Value Of Testsen_US
dc.subject.meshRetrospective Studiesen_US
dc.titleCardiovascular symptoms and signs in evaluating cardiac murmurs in childrenen_US
dc.typeArticleen_US
dc.identifier.emailCheung, YF:xfcheung@hku.hken_US
dc.identifier.authorityCheung, YF=rp00382en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1111/j.1442-200X.2008.02560.xen_US
dc.identifier.pmid18353047en_US
dc.identifier.scopuseid_2-s2.0-40949121106en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-40949121106&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume50en_US
dc.identifier.issue2en_US
dc.identifier.spage145en_US
dc.identifier.epage149en_US
dc.identifier.isiWOS:000254054800001-
dc.publisher.placeAustraliaen_US
dc.identifier.scopusauthoridKoo, S=23980457100en_US
dc.identifier.scopusauthoridYung, TC=9132842300en_US
dc.identifier.scopusauthoridLun, KS=8363663600en_US
dc.identifier.scopusauthoridChau, AKT=35787094400en_US
dc.identifier.scopusauthoridCheung, YF=7202111067en_US

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