Article: Midterm outcomes of transcatheter closure of atrial septal defect using the amplatzer septal occluder in children
| Title | Midterm outcomes of transcatheter closure of atrial septal defect using the amplatzer septal occluder in children |
|---|---|
| Authors | Chau, AKT1 Chung, BHY1 Lun, KS1 Cheung, YF1 Yung, TC1 |
| Keywords | Amplatzer Septal Occluder Children Secundum Atrial Septal Defect Transcatheter Closure |
| Issue Date | 2005 |
| Publisher | Medcom Limited. The Journal's web site is located at http://www.hkjpaed.org/index.asp |
| Citation | Hong Kong Journal Of Paediatrics, 2005, v. 10 n. 4, p. 251-256+311 [How to Cite?] |
| Abstract | Purpose: This study reports the clinical experience and midterm outcomes of transcatheter closure of secundum atrial septal defect with the Amplatzer septal occluder in children. Methods: From April 1998 to June 2002, 41 children (male = 14) with a median age of 11.0 years (range = 3.2-18.9 years) and median weight of 31.5 kg (range = 13.5-65 kg) underwent transcatheter closure of secundum atrial septal defect using the Amplatzer Septal Occluder after a detailed pre-implantation evaluation. The procedures were performed under general anaesthesia with fluoroscopic guidance and transesophageal echocardiographic monitoring. The size of the device deployed was determined by the balloon-stretched diameter of the defect. Patients were followed for any residual shunts and possible complications. Results: The mean diameter of atrial septal defect measured by transesophageal echocardiography was 14.3±4.1 mm and 19.2±4.7 mm by balloon-stretched diameter. The mean device diameter was 19.2±4.7 mm (range = 11-30 mm). The mean fluoroscopy time was 17.3 minutes (range = 7.4 to 30 minutes) and the mean procedure time was 100 minutes (range = 35-190 minutes). All devices were successfully deployed. Two patients developed transient atrioventricular dissociation with spontaneous recovery. Complete closure rate at 24 hours, one week, one, 6 and 12 months were 83% [90% confidence limit (CL): 73-91%], 93% (90% CL: 84-97%), 95% (90% CL: 81-96%) and 97% (90% CL: 91-99%), respectively. The mean follow-up period was 46.5±18.6 months (range = 10.7-86.6 months). All devices were in stable position with no late complications. Conclusions: Transcatheter closure of atrial septal defect using the Amplatzer Septal Occluder is safe and effective in children. The midterm results are excellent. However, long-term follow-up is needed to ascertain the absence of possible late complications. |
| ISSN | 1013-9923 2011 Impact Factor: 0.027 2011 SCImago Journal Rankings: 0.029 |
| References | References in Scopus |
| dc.contributor.author | Chau, AKT |
|---|---|
| dc.contributor.author | Chung, BHY |
| dc.contributor.author | Lun, KS |
| dc.contributor.author | Cheung, YF |
| dc.contributor.author | Yung, TC |
| dc.date.accessioned | 2012-10-30T06:07:45Z |
| dc.date.available | 2012-10-30T06:07:45Z |
| dc.date.issued | 2005 |
| dc.description.abstract | Purpose: This study reports the clinical experience and midterm outcomes of transcatheter closure of secundum atrial septal defect with the Amplatzer septal occluder in children. Methods: From April 1998 to June 2002, 41 children (male = 14) with a median age of 11.0 years (range = 3.2-18.9 years) and median weight of 31.5 kg (range = 13.5-65 kg) underwent transcatheter closure of secundum atrial septal defect using the Amplatzer Septal Occluder after a detailed pre-implantation evaluation. The procedures were performed under general anaesthesia with fluoroscopic guidance and transesophageal echocardiographic monitoring. The size of the device deployed was determined by the balloon-stretched diameter of the defect. Patients were followed for any residual shunts and possible complications. Results: The mean diameter of atrial septal defect measured by transesophageal echocardiography was 14.3±4.1 mm and 19.2±4.7 mm by balloon-stretched diameter. The mean device diameter was 19.2±4.7 mm (range = 11-30 mm). The mean fluoroscopy time was 17.3 minutes (range = 7.4 to 30 minutes) and the mean procedure time was 100 minutes (range = 35-190 minutes). All devices were successfully deployed. Two patients developed transient atrioventricular dissociation with spontaneous recovery. Complete closure rate at 24 hours, one week, one, 6 and 12 months were 83% [90% confidence limit (CL): 73-91%], 93% (90% CL: 84-97%), 95% (90% CL: 81-96%) and 97% (90% CL: 91-99%), respectively. The mean follow-up period was 46.5±18.6 months (range = 10.7-86.6 months). All devices were in stable position with no late complications. Conclusions: Transcatheter closure of atrial septal defect using the Amplatzer Septal Occluder is safe and effective in children. The midterm results are excellent. However, long-term follow-up is needed to ascertain the absence of possible late complications. |
| dc.description.nature | Link_to_subscribed_fulltext |
| dc.identifier.citation | Hong Kong Journal Of Paediatrics, 2005, v. 10 n. 4, p. 251-256+311 [How to Cite?] |
| dc.identifier.epage | 256+311 |
| dc.identifier.issn | 1013-9923 2011 Impact Factor: 0.027 2011 SCImago Journal Rankings: 0.029 |
| dc.identifier.issue | 4 |
| dc.identifier.scopus | eid_2-s2.0-27644558928 |
| dc.identifier.spage | 251 |
| dc.identifier.uri | http://hdl.handle.net/10722/170356 |
| dc.identifier.volume | 10 |
| dc.language | eng |
| dc.publisher | Medcom Limited. The Journal's web site is located at http://www.hkjpaed.org/index.asp |
| dc.publisher.place | Hong Kong |
| dc.relation.ispartof | Hong Kong Journal of Paediatrics |
| dc.relation.references | References in Scopus |
| dc.subject | Amplatzer Septal Occluder |
| dc.subject | Children |
| dc.subject | Secundum Atrial Septal Defect |
| dc.subject | Transcatheter Closure |
| dc.title | Midterm outcomes of transcatheter closure of atrial septal defect using the amplatzer septal occluder in children |
| dc.type | Article |
Author Affiliations
- The University of Hong Kong