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Article: Midterm outcomes of transcatheter closure of atrial septal defect using the amplatzer septal occluder in children
Title | Midterm outcomes of transcatheter closure of atrial septal defect using the amplatzer septal occluder in children |
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Authors | |
Keywords | Amplatzer Septal Occluder Children Secundum Atrial Septal Defect Transcatheter Closure |
Issue Date | 2005 |
Publisher | Medcom Limited. The Journal's web site is located at http://www.hkjpaed.org/index.asp |
Citation | Hong Kong Journal Of Paediatrics, 2005, v. 10 n. 4, p. 251-256+311 How to Cite? |
Abstract | Purpose: This study reports the clinical experience and midterm outcomes of transcatheter closure of secundum atrial septal defect with the Amplatzer septal occluder in children. Methods: From April 1998 to June 2002, 41 children (male = 14) with a median age of 11.0 years (range = 3.2-18.9 years) and median weight of 31.5 kg (range = 13.5-65 kg) underwent transcatheter closure of secundum atrial septal defect using the Amplatzer Septal Occluder after a detailed pre-implantation evaluation. The procedures were performed under general anaesthesia with fluoroscopic guidance and transesophageal echocardiographic monitoring. The size of the device deployed was determined by the balloon-stretched diameter of the defect. Patients were followed for any residual shunts and possible complications. Results: The mean diameter of atrial septal defect measured by transesophageal echocardiography was 14.3±4.1 mm and 19.2±4.7 mm by balloon-stretched diameter. The mean device diameter was 19.2±4.7 mm (range = 11-30 mm). The mean fluoroscopy time was 17.3 minutes (range = 7.4 to 30 minutes) and the mean procedure time was 100 minutes (range = 35-190 minutes). All devices were successfully deployed. Two patients developed transient atrioventricular dissociation with spontaneous recovery. Complete closure rate at 24 hours, one week, one, 6 and 12 months were 83% [90% confidence limit (CL): 73-91%], 93% (90% CL: 84-97%), 95% (90% CL: 81-96%) and 97% (90% CL: 91-99%), respectively. The mean follow-up period was 46.5±18.6 months (range = 10.7-86.6 months). All devices were in stable position with no late complications. Conclusions: Transcatheter closure of atrial septal defect using the Amplatzer Septal Occluder is safe and effective in children. The midterm results are excellent. However, long-term follow-up is needed to ascertain the absence of possible late complications. |
Persistent Identifier | http://hdl.handle.net/10722/170356 |
ISSN | 2023 Impact Factor: 0.1 2023 SCImago Journal Rankings: 0.117 |
References |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Chau, AKT | en_US |
dc.contributor.author | Chung, BHY | en_US |
dc.contributor.author | Lun, KS | en_US |
dc.contributor.author | Cheung, YF | en_US |
dc.contributor.author | Yung, TC | en_US |
dc.date.accessioned | 2012-10-30T06:07:45Z | - |
dc.date.available | 2012-10-30T06:07:45Z | - |
dc.date.issued | 2005 | en_US |
dc.identifier.citation | Hong Kong Journal Of Paediatrics, 2005, v. 10 n. 4, p. 251-256+311 | en_US |
dc.identifier.issn | 1013-9923 | en_US |
dc.identifier.uri | http://hdl.handle.net/10722/170356 | - |
dc.description.abstract | Purpose: This study reports the clinical experience and midterm outcomes of transcatheter closure of secundum atrial septal defect with the Amplatzer septal occluder in children. Methods: From April 1998 to June 2002, 41 children (male = 14) with a median age of 11.0 years (range = 3.2-18.9 years) and median weight of 31.5 kg (range = 13.5-65 kg) underwent transcatheter closure of secundum atrial septal defect using the Amplatzer Septal Occluder after a detailed pre-implantation evaluation. The procedures were performed under general anaesthesia with fluoroscopic guidance and transesophageal echocardiographic monitoring. The size of the device deployed was determined by the balloon-stretched diameter of the defect. Patients were followed for any residual shunts and possible complications. Results: The mean diameter of atrial septal defect measured by transesophageal echocardiography was 14.3±4.1 mm and 19.2±4.7 mm by balloon-stretched diameter. The mean device diameter was 19.2±4.7 mm (range = 11-30 mm). The mean fluoroscopy time was 17.3 minutes (range = 7.4 to 30 minutes) and the mean procedure time was 100 minutes (range = 35-190 minutes). All devices were successfully deployed. Two patients developed transient atrioventricular dissociation with spontaneous recovery. Complete closure rate at 24 hours, one week, one, 6 and 12 months were 83% [90% confidence limit (CL): 73-91%], 93% (90% CL: 84-97%), 95% (90% CL: 81-96%) and 97% (90% CL: 91-99%), respectively. The mean follow-up period was 46.5±18.6 months (range = 10.7-86.6 months). All devices were in stable position with no late complications. Conclusions: Transcatheter closure of atrial septal defect using the Amplatzer Septal Occluder is safe and effective in children. The midterm results are excellent. However, long-term follow-up is needed to ascertain the absence of possible late complications. | en_US |
dc.language | eng | en_US |
dc.publisher | Medcom Limited. The Journal's web site is located at http://www.hkjpaed.org/index.asp | en_US |
dc.relation.ispartof | Hong Kong Journal of Paediatrics | en_US |
dc.subject | Amplatzer Septal Occluder | en_US |
dc.subject | Children | en_US |
dc.subject | Secundum Atrial Septal Defect | en_US |
dc.subject | Transcatheter Closure | en_US |
dc.title | Midterm outcomes of transcatheter closure of atrial septal defect using the amplatzer septal occluder in children | en_US |
dc.type | Article | en_US |
dc.identifier.email | Chung, BHY:bhychung@hku.hk | en_US |
dc.identifier.email | Cheung, YF:xfcheung@hku.hk | en_US |
dc.identifier.authority | Chung, BHY=rp00473 | en_US |
dc.identifier.authority | Cheung, YF=rp00382 | en_US |
dc.description.nature | link_to_subscribed_fulltext | en_US |
dc.identifier.scopus | eid_2-s2.0-27644558928 | en_US |
dc.relation.references | http://www.scopus.com/mlt/select.url?eid=2-s2.0-27644558928&selection=ref&src=s&origin=recordpage | en_US |
dc.identifier.volume | 10 | en_US |
dc.identifier.issue | 4 | en_US |
dc.identifier.spage | 251 | en_US |
dc.identifier.epage | 256+311 | en_US |
dc.publisher.place | Hong Kong | en_US |
dc.identifier.scopusauthorid | Chau, AKT=35787094400 | en_US |
dc.identifier.scopusauthorid | Chung, BHY=7203043997 | en_US |
dc.identifier.scopusauthorid | Lun, KS=8363663600 | en_US |
dc.identifier.scopusauthorid | Cheung, YF=7202111067 | en_US |
dc.identifier.scopusauthorid | Yung, TC=9132842300 | en_US |
dc.identifier.issnl | 1013-9923 | - |