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Article: Midterm results of transcatheter closure of moderate to large-sized patent ductus arteriosus using the amplatzer duct occluder
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TitleMidterm results of transcatheter closure of moderate to large-sized patent ductus arteriosus using the amplatzer duct occluder
 
AuthorsWong, KT1
Chau, AKT1
Cheung, YF1
Yung, TC1
Lun, KS1
 
KeywordsAmplatzer Duct Occluder
Children
Patent Ductus Arteriosus
Transcatheter Closure
 
Issue Date2005
 
PublisherMedcom Limited. The Journal's web site is located at http://www.hkjpaed.org/index.asp
 
CitationHong Kong Journal Of Paediatrics, 2005, v. 10 n. 4, p. 245-250+311 [How to Cite?]
 
AbstractTranscatheter closure is an established form of treatment for most patients with patent ductus arteriosus (PDA). The design of previously used devices has been associated with several drawbacks for closing moderate to large PDAs. The aim of this study was to examine the midterm results of transcatheter closure of moderate to large-sized PDA using the Amplatzer Duct Occluder (ADO). Ninety patients, aged 2.9 months to 16.5 years with a moderate to large-sized PDA, underwent successful transcatheter closure using the ADO. The median PDA diameter was 2.8 mm (range 1.5 to 5.0 mm). Complete immediate angiographic closure was seen in 34 of 90 patients (37.7%; 95% CI 27.7% to 47.7%). On colour Doppler interrogation, the closure rates at 1 day, 1 month and 3 months after implant were 81.1% (95% CI 73.0% to 89.2%), 88.9% (95% CI 82.5% to 95.3%) and 93.3% (95% CI 88.1% to 98.5%) respectively. At 12 months, all patients had complete closure. The median fluoroscopy time was 11.5 minutes (range 3 to 49.5 minutes) and the median procedure time was 68 minutes (range 32 to 180 minutes). Mild device-related turbulent blood flow but with no significant obstruction occurred in the left pulmonary artery of two patients and the descending aorta of another patient who had pre-existing isthmal hypoplasia. No device embolisation was encountered. Therefore transcatheter closure of moderate to large-sided PDA using the ADO is an effective and safe therapy. Further studies are required to establish long-term results in a larger patient population.
 
ISSN1013-9923
2012 Impact Factor: 0.068
2012 SCImago Journal Rankings: 0.107
 
ReferencesReferences in Scopus
 
DC FieldValue
dc.contributor.authorWong, KT
 
dc.contributor.authorChau, AKT
 
dc.contributor.authorCheung, YF
 
dc.contributor.authorYung, TC
 
dc.contributor.authorLun, KS
 
dc.date.accessioned2012-10-30T06:07:44Z
 
dc.date.available2012-10-30T06:07:44Z
 
dc.date.issued2005
 
dc.description.abstractTranscatheter closure is an established form of treatment for most patients with patent ductus arteriosus (PDA). The design of previously used devices has been associated with several drawbacks for closing moderate to large PDAs. The aim of this study was to examine the midterm results of transcatheter closure of moderate to large-sized PDA using the Amplatzer Duct Occluder (ADO). Ninety patients, aged 2.9 months to 16.5 years with a moderate to large-sized PDA, underwent successful transcatheter closure using the ADO. The median PDA diameter was 2.8 mm (range 1.5 to 5.0 mm). Complete immediate angiographic closure was seen in 34 of 90 patients (37.7%; 95% CI 27.7% to 47.7%). On colour Doppler interrogation, the closure rates at 1 day, 1 month and 3 months after implant were 81.1% (95% CI 73.0% to 89.2%), 88.9% (95% CI 82.5% to 95.3%) and 93.3% (95% CI 88.1% to 98.5%) respectively. At 12 months, all patients had complete closure. The median fluoroscopy time was 11.5 minutes (range 3 to 49.5 minutes) and the median procedure time was 68 minutes (range 32 to 180 minutes). Mild device-related turbulent blood flow but with no significant obstruction occurred in the left pulmonary artery of two patients and the descending aorta of another patient who had pre-existing isthmal hypoplasia. No device embolisation was encountered. Therefore transcatheter closure of moderate to large-sided PDA using the ADO is an effective and safe therapy. Further studies are required to establish long-term results in a larger patient population.
 
dc.description.natureLink_to_subscribed_fulltext
 
dc.identifier.citationHong Kong Journal Of Paediatrics, 2005, v. 10 n. 4, p. 245-250+311 [How to Cite?]
 
dc.identifier.epage250+311
 
dc.identifier.issn1013-9923
2012 Impact Factor: 0.068
2012 SCImago Journal Rankings: 0.107
 
dc.identifier.issue4
 
dc.identifier.scopuseid_2-s2.0-27644475761
 
dc.identifier.spage245
 
dc.identifier.urihttp://hdl.handle.net/10722/170353
 
dc.identifier.volume10
 
dc.languageeng
 
dc.publisherMedcom Limited. The Journal's web site is located at http://www.hkjpaed.org/index.asp
 
dc.publisher.placeHong Kong
 
dc.relation.ispartofHong Kong Journal of Paediatrics
 
dc.relation.referencesReferences in Scopus
 
dc.subjectAmplatzer Duct Occluder
 
dc.subjectChildren
 
dc.subjectPatent Ductus Arteriosus
 
dc.subjectTranscatheter Closure
 
dc.titleMidterm results of transcatheter closure of moderate to large-sized patent ductus arteriosus using the amplatzer duct occluder
 
dc.typeArticle
 
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<contributor.author>Lun, KS</contributor.author>
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Author Affiliations
  1. Grantham Hospital Hong Kong