Article: Midterm results of transcatheter closure of moderate to large-sized patent ductus arteriosus using the amplatzer duct occluder

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TitleMidterm results of transcatheter closure of moderate to large-sized patent ductus arteriosus using the amplatzer duct occluder
AuthorsWong, KT1
Chau, AKT1
Cheung, YF1
Yung, TC1
Lun, KS1
KeywordsAmplatzer Duct Occluder
Children
Patent Ductus Arteriosus
Transcatheter Closure
Issue Date2005
PublisherMedcom Limited. The Journal's web site is located at http://www.hkjpaed.org/index.asp
CitationHong Kong Journal Of Paediatrics, 2005, v. 10 n. 4, p. 245-250+311 [How to Cite?]
AbstractTranscatheter closure is an established form of treatment for most patients with patent ductus arteriosus (PDA). The design of previously used devices has been associated with several drawbacks for closing moderate to large PDAs. The aim of this study was to examine the midterm results of transcatheter closure of moderate to large-sized PDA using the Amplatzer Duct Occluder (ADO). Ninety patients, aged 2.9 months to 16.5 years with a moderate to large-sized PDA, underwent successful transcatheter closure using the ADO. The median PDA diameter was 2.8 mm (range 1.5 to 5.0 mm). Complete immediate angiographic closure was seen in 34 of 90 patients (37.7%; 95% CI 27.7% to 47.7%). On colour Doppler interrogation, the closure rates at 1 day, 1 month and 3 months after implant were 81.1% (95% CI 73.0% to 89.2%), 88.9% (95% CI 82.5% to 95.3%) and 93.3% (95% CI 88.1% to 98.5%) respectively. At 12 months, all patients had complete closure. The median fluoroscopy time was 11.5 minutes (range 3 to 49.5 minutes) and the median procedure time was 68 minutes (range 32 to 180 minutes). Mild device-related turbulent blood flow but with no significant obstruction occurred in the left pulmonary artery of two patients and the descending aorta of another patient who had pre-existing isthmal hypoplasia. No device embolisation was encountered. Therefore transcatheter closure of moderate to large-sided PDA using the ADO is an effective and safe therapy. Further studies are required to establish long-term results in a larger patient population.
ISSN1013-9923
2011 Impact Factor: 0.027
2011 SCImago Journal Rankings: 0.029
ReferencesReferences in Scopus
DC Field
Value
dc.contributor.authorWong, KT
dc.contributor.authorChau, AKT
dc.contributor.authorCheung, YF
dc.contributor.authorYung, TC
dc.contributor.authorLun, KS
dc.date.accessioned2012-10-30T06:07:44Z
dc.date.available2012-10-30T06:07:44Z
dc.date.issued2005
dc.description.abstractTranscatheter closure is an established form of treatment for most patients with patent ductus arteriosus (PDA). The design of previously used devices has been associated with several drawbacks for closing moderate to large PDAs. The aim of this study was to examine the midterm results of transcatheter closure of moderate to large-sized PDA using the Amplatzer Duct Occluder (ADO). Ninety patients, aged 2.9 months to 16.5 years with a moderate to large-sized PDA, underwent successful transcatheter closure using the ADO. The median PDA diameter was 2.8 mm (range 1.5 to 5.0 mm). Complete immediate angiographic closure was seen in 34 of 90 patients (37.7%; 95% CI 27.7% to 47.7%). On colour Doppler interrogation, the closure rates at 1 day, 1 month and 3 months after implant were 81.1% (95% CI 73.0% to 89.2%), 88.9% (95% CI 82.5% to 95.3%) and 93.3% (95% CI 88.1% to 98.5%) respectively. At 12 months, all patients had complete closure. The median fluoroscopy time was 11.5 minutes (range 3 to 49.5 minutes) and the median procedure time was 68 minutes (range 32 to 180 minutes). Mild device-related turbulent blood flow but with no significant obstruction occurred in the left pulmonary artery of two patients and the descending aorta of another patient who had pre-existing isthmal hypoplasia. No device embolisation was encountered. Therefore transcatheter closure of moderate to large-sided PDA using the ADO is an effective and safe therapy. Further studies are required to establish long-term results in a larger patient population.
dc.description.natureLink_to_subscribed_fulltext
dc.identifier.citationHong Kong Journal Of Paediatrics, 2005, v. 10 n. 4, p. 245-250+311 [How to Cite?]
dc.identifier.epage250+311
dc.identifier.issn1013-9923
2011 Impact Factor: 0.027
2011 SCImago Journal Rankings: 0.029
dc.identifier.issue4
dc.identifier.scopuseid_2-s2.0-27644475761
dc.identifier.spage245
dc.identifier.urihttp://hdl.handle.net/10722/170353
dc.identifier.volume10
dc.languageeng
dc.publisherMedcom Limited. The Journal's web site is located at http://www.hkjpaed.org/index.asp
dc.publisher.placeHong Kong
dc.relation.ispartofHong Kong Journal of Paediatrics
dc.relation.referencesReferences in Scopus
dc.subjectAmplatzer Duct Occluder
dc.subjectChildren
dc.subjectPatent Ductus Arteriosus
dc.subjectTranscatheter Closure
dc.titleMidterm results of transcatheter closure of moderate to large-sized patent ductus arteriosus using the amplatzer duct occluder
dc.typeArticle
Author Affiliations
  1. Grantham Hospital Hong Kong