File Download

Conference Paper: The prognostic and therapeutic potential of AMP-activated protein kinase in ovarian cancer

TitleThe prognostic and therapeutic potential of AMP-activated protein kinase in ovarian cancer
Authors
Issue Date2012
PublisherAsian Society of Gynecologic Oncology (ASGO).
Citation
The 2nd International Workshop on Gynecologic Oncology (ASGO 2012), Kyoto, Japan, 28 September 2012. In Conference Program, 2012, p. 32 How to Cite?
AbstractOvarian cancer is one of the leading causes of cancer-associated death in women. The high mortality is due to its poor prognosis as most cases are found in late stages. Therefore, searching reliable tumor markers is urgently needed for clinical management of this disease. Altered cellular metabolism is a crucial phenomenon for the development and progression of ovarian cancer. AMP-activated protein kinase (AMPK) acts as a key intracellular energy sensor and regulator for governing energy balance homeostasis. It also closely links with cancer cell metabolism. Others and we have reported that the activation of AMPK by pharmacological agents shows cytotoxicity to cancer cells, indicating that targeting AMPK could be a promising therapeutic approach. On the other hand, our study also demonstrated that the AMPK activity had an inversely correlation between tumor stage and/or high grade ovarian cancer. Import...
DescriptionTopics 3 - Translational Research for Ovarian Cancer: no. 3-2
Persistent Identifierhttp://hdl.handle.net/10722/169438

 

DC FieldValueLanguage
dc.contributor.authorChan, DWen_US
dc.contributor.authorNgan, HYSen_US
dc.date.accessioned2012-10-18T08:55:08Z-
dc.date.available2012-10-18T08:55:08Z-
dc.date.issued2012en_US
dc.identifier.citationThe 2nd International Workshop on Gynecologic Oncology (ASGO 2012), Kyoto, Japan, 28 September 2012. In Conference Program, 2012, p. 32en_US
dc.identifier.urihttp://hdl.handle.net/10722/169438-
dc.descriptionTopics 3 - Translational Research for Ovarian Cancer: no. 3-2-
dc.description.abstractOvarian cancer is one of the leading causes of cancer-associated death in women. The high mortality is due to its poor prognosis as most cases are found in late stages. Therefore, searching reliable tumor markers is urgently needed for clinical management of this disease. Altered cellular metabolism is a crucial phenomenon for the development and progression of ovarian cancer. AMP-activated protein kinase (AMPK) acts as a key intracellular energy sensor and regulator for governing energy balance homeostasis. It also closely links with cancer cell metabolism. Others and we have reported that the activation of AMPK by pharmacological agents shows cytotoxicity to cancer cells, indicating that targeting AMPK could be a promising therapeutic approach. On the other hand, our study also demonstrated that the AMPK activity had an inversely correlation between tumor stage and/or high grade ovarian cancer. Import...-
dc.languageengen_US
dc.publisherAsian Society of Gynecologic Oncology (ASGO).-
dc.relation.ispartofInternational Workshop on Gynecologic Oncology, ASGO 2012en_US
dc.rightsThis work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.-
dc.titleThe prognostic and therapeutic potential of AMP-activated protein kinase in ovarian canceren_US
dc.typeConference_Paperen_US
dc.identifier.emailChan, DW: dwchan@hku.hken_US
dc.identifier.emailNgan, HYS: hysngan@hkucc.hku.hken_US
dc.identifier.authorityChan, DW=rp00543en_US
dc.identifier.authorityNgan, HYS=rp00346en_US
dc.description.naturepostprint-
dc.identifier.hkuros212234en_US
dc.identifier.spage32-
dc.identifier.epage32-

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats