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Conference Paper: Downregulation of ASPP2 in choriocarcinoma contributes to increased migratory potential through Src activation
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TitleDownregulation of ASPP2 in choriocarcinoma contributes to increased migratory potential through Src activation
 
AuthorsMak, VCY
Lee, L
Siu, MKY
Wong, OGW
Lu, X
Ngan, HYS
Wong, ESY
Cheung, ANY
 
Issue Date2011
 
PublisherAmerican Association for Cancer Research.
 
CitationThe 102nd Annual Meeting of the American Association for Cancer Research (AACR 2011), Orlando, FL., 2-6 April 2011. [How to Cite?]
 
AbstractGestational choriocarcinoma is a malignant tumour derived from placental trophoblast and is the most aggressive member of gestational trophoblastic disease (GTD). Apoptotic stimulating protein of p53-2 (ASPP2) is a tumor suppressor member of the ASPP family which transactivates p53-dependent apoptotic pathway. In this study, we examined the expression profile of ASPP2 in choriocarcinoma in comparison with normal placentas and hydatidiform moles which is a type of GTD that carries malignant potential. Results from quantitative PCR and immunohistochemical studies showed that downregulation of ASPP2 was detected in ...
 
DescriptionPoster Session 7 - Signaling Pathways Involved in Oncogenesis and Tumor Suppression: abstract no. 2107
 
DC FieldValue
dc.contributor.authorMak, VCY
 
dc.contributor.authorLee, L
 
dc.contributor.authorSiu, MKY
 
dc.contributor.authorWong, OGW
 
dc.contributor.authorLu, X
 
dc.contributor.authorNgan, HYS
 
dc.contributor.authorWong, ESY
 
dc.contributor.authorCheung, ANY
 
dc.date.accessioned2012-10-18T08:52:10Z
 
dc.date.available2012-10-18T08:52:10Z
 
dc.date.issued2011
 
dc.description.abstractGestational choriocarcinoma is a malignant tumour derived from placental trophoblast and is the most aggressive member of gestational trophoblastic disease (GTD). Apoptotic stimulating protein of p53-2 (ASPP2) is a tumor suppressor member of the ASPP family which transactivates p53-dependent apoptotic pathway. In this study, we examined the expression profile of ASPP2 in choriocarcinoma in comparison with normal placentas and hydatidiform moles which is a type of GTD that carries malignant potential. Results from quantitative PCR and immunohistochemical studies showed that downregulation of ASPP2 was detected in ...
 
dc.description.naturelink_to_OA_fulltext
 
dc.descriptionPoster Session 7 - Signaling Pathways Involved in Oncogenesis and Tumor Suppression: abstract no. 2107
 
dc.description.otherThe 102nd Annual Meeting of the American Association for Cancer Research (AACR 2011), Orlando, FL., 2-6 April 2011.
 
dc.identifier.citationThe 102nd Annual Meeting of the American Association for Cancer Research (AACR 2011), Orlando, FL., 2-6 April 2011. [How to Cite?]
 
dc.identifier.hkuros212024
 
dc.identifier.urihttp://hdl.handle.net/10722/169374
 
dc.languageeng
 
dc.publisherAmerican Association for Cancer Research.
 
dc.publisher.placeUnited States
 
dc.relation.ispartofAnnual Meeting of the American Association for Cancer Research, AACR 2011
 
dc.titleDownregulation of ASPP2 in choriocarcinoma contributes to increased migratory potential through Src activation
 
dc.typeConference_Paper
 
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<contributor.author>Lee, L</contributor.author>
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<contributor.author>Lu, X</contributor.author>
<contributor.author>Ngan, HYS</contributor.author>
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