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Conference Paper: Dissolved oxygen sensing using organometallic dyes deposited within a microfluidic environment

TitleDissolved oxygen sensing using organometallic dyes deposited within a microfluidic environment
Authors
KeywordsCovalent Attachment
Microfluidics
Oxygen Sensing
Issue Date2008
PublisherS P I E - International Society for Optical Engineering. The Journal's web site is located at http://spie.org/x1848.xml
Citation
Proceedings Of Spie - The International Society For Optical Engineering, 2008, v. 6886 How to Cite?
Abstract
This work primarily aims to integrate dissolved oxygen sensing capability with a microfluidic platform containing arrays of micro bio-reactors or bio-activity indicators. The measurement of oxygen concentration is of significance for a variety of bio-related applications such as cell culture and gene expression. Optical oxygen sensors based on luminescence quenching are gaining much interest in light of their low power consumption, quick response and high analyte sensitivity in comparison to similar oxygen sensing devices. In our microfluidic oxygen sensor device, a thin layer of oxygen-sensitive luminescent organometallic dye is covalently bonded to a glass slide. Micro flow channels are formed on the glass slide using patterned PDMS (Polydimethylsiloxane). Dissolved oxygen sensing is then performed by directing an optical excitation probe beam to the area of interest within the microfluidic channel. The covalent bonding approach for sensor layer formation offers many distinct advantages over the physical entrapment method including minimizing dye leaching, ensuring good stability and fabrication simplicity. Experimental results confirm the feasibility of the device.
Persistent Identifierhttp://hdl.handle.net/10722/168842
ISSN
2013 SCImago Journal Rankings: 0.203
References

 

Author Affiliations
  1. Institute of Molecular Technology for Drug Discovery and Synthesis, Hong Kong
  2. Chinese University of Hong Kong
DC FieldValueLanguage
dc.contributor.authorChen, QLen_US
dc.contributor.authorHo, HPen_US
dc.contributor.authorJin, Len_US
dc.contributor.authorChu, BWKen_US
dc.contributor.authorLi, MJen_US
dc.contributor.authorYam, VWWen_US
dc.date.accessioned2012-10-08T03:34:57Z-
dc.date.available2012-10-08T03:34:57Z-
dc.date.issued2008en_US
dc.identifier.citationProceedings Of Spie - The International Society For Optical Engineering, 2008, v. 6886en_US
dc.identifier.issn0277-786Xen_US
dc.identifier.urihttp://hdl.handle.net/10722/168842-
dc.description.abstractThis work primarily aims to integrate dissolved oxygen sensing capability with a microfluidic platform containing arrays of micro bio-reactors or bio-activity indicators. The measurement of oxygen concentration is of significance for a variety of bio-related applications such as cell culture and gene expression. Optical oxygen sensors based on luminescence quenching are gaining much interest in light of their low power consumption, quick response and high analyte sensitivity in comparison to similar oxygen sensing devices. In our microfluidic oxygen sensor device, a thin layer of oxygen-sensitive luminescent organometallic dye is covalently bonded to a glass slide. Micro flow channels are formed on the glass slide using patterned PDMS (Polydimethylsiloxane). Dissolved oxygen sensing is then performed by directing an optical excitation probe beam to the area of interest within the microfluidic channel. The covalent bonding approach for sensor layer formation offers many distinct advantages over the physical entrapment method including minimizing dye leaching, ensuring good stability and fabrication simplicity. Experimental results confirm the feasibility of the device.en_US
dc.languageengen_US
dc.publisherS P I E - International Society for Optical Engineering. The Journal's web site is located at http://spie.org/x1848.xmlen_US
dc.relation.ispartofProceedings of SPIE - The International Society for Optical Engineeringen_US
dc.subjectCovalent Attachmenten_US
dc.subjectMicrofluidicsen_US
dc.subjectOxygen Sensingen_US
dc.titleDissolved oxygen sensing using organometallic dyes deposited within a microfluidic environmenten_US
dc.typeConference_Paperen_US
dc.identifier.emailYam, VWW:wwyam@hku.hken_US
dc.identifier.authorityYam, VWW=rp00822en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1117/12.762666en_US
dc.identifier.scopuseid_2-s2.0-41149102859en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-41149102859&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume6886en_US
dc.publisher.placeUnited Statesen_US
dc.identifier.scopusauthoridChen, QL=19642314100en_US
dc.identifier.scopusauthoridHo, HP=35175860200en_US
dc.identifier.scopusauthoridJin, L=35268904100en_US
dc.identifier.scopusauthoridChu, BWK=35209639800en_US
dc.identifier.scopusauthoridLi, MJ=13105838700en_US
dc.identifier.scopusauthoridYam, VWW=18539304700en_US

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