Conference Paper: Adipocyte-selective disruption of SIRT1 accelerates high fat diet- and aging-induced insulin resistance by inducing cellular senescence in mice
| Title | Adipocyte-selective disruption of SIRT1 accelerates high fat diet- and aging-induced insulin resistance by inducing cellular senescence in mice |
|---|---|
| Authors | Hui, X Lam, KSL Xu, A |
| Keywords | Medical sciences |
| Issue Date | 2012 |
| Publisher | Hong Kong Academy of Medicine Press. The Journal's web site is located at http://www.hkmj.org.hk |
| Citation | The 17th Medical Research Conference (17th MRC), Hong Kong, 14 January 2012. In Hong Kong Medical Journal, 2012, v. 18 suppl. 1, p. 26, abstract no. 31 [How to Cite?] |
| Abstract | OBJECTIVE: SIRT1 is an NAD+-dependent histone deacetylase that antagonises ageing-associated diseases in multiple tissues. However, the physiological function of SIRT1 in adipocytes remains unknown. This study sought to address whether and how adipocyte SIRT1 modulates the systemic energy homeostasis and ... |
| ISSN | 1024-2708 2011 SCImago Journal Rankings: 0.054 |
| dc.contributor.author | Hui, X |
|---|---|
| dc.contributor.author | Lam, KSL |
| dc.contributor.author | Xu, A |
| dc.date.accessioned | 2012-09-20T08:18:11Z |
| dc.date.available | 2012-09-20T08:18:11Z |
| dc.date.issued | 2012 |
| dc.description.abstract | OBJECTIVE: SIRT1 is an NAD+-dependent histone deacetylase that antagonises ageing-associated diseases in multiple tissues. However, the physiological function of SIRT1 in adipocytes remains unknown. This study sought to address whether and how adipocyte SIRT1 modulates the systemic energy homeostasis and ... |
| dc.description.nature | published_or_final_version |
| dc.description.other | The 17th Medical Research Conference (17th MRC), Hong Kong, 14 January 2012. In Hong Kong Medical Journal, 2012, v. 18 suppl. 1, p. 26, abstract no. 31 |
| dc.identifier.citation | The 17th Medical Research Conference (17th MRC), Hong Kong, 14 January 2012. In Hong Kong Medical Journal, 2012, v. 18 suppl. 1, p. 26, abstract no. 31 [How to Cite?] |
| dc.identifier.epage | 26 |
| dc.identifier.hkuros | 206402 |
| dc.identifier.issn | 1024-2708 2011 SCImago Journal Rankings: 0.054 |
| dc.identifier.issue | suppl. 1 |
| dc.identifier.spage | 26 |
| dc.identifier.uri | http://hdl.handle.net/10722/165424 |
| dc.identifier.volume | 18 |
| dc.language | eng |
| dc.publisher | Hong Kong Academy of Medicine Press. The Journal's web site is located at http://www.hkmj.org.hk |
| dc.publisher.place | Hong Kong |
| dc.relation.ispartof | Hong Kong Medical Journal |
| dc.rights | Hong Kong Medical Journal. Copyright © Hong Kong Academy of Medicine Press. |
| dc.rights | Creative Commons: Attribution 3.0 Hong Kong License |
| dc.subject | Medical sciences |
| dc.title | Adipocyte-selective disruption of SIRT1 accelerates high fat diet- and aging-induced insulin resistance by inducing cellular senescence in mice |
| dc.type | Conference_Paper |