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- Publisher Website: 10.1016/j.vaccine.2012.02.009
- Scopus: eid_2-s2.0-84862809138
- PMID: 22342549
- WOS: WOS:000302663200001
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Article: Anti-ganglioside antibodies were not detected in human subjects infected with or vaccinated against 2009 pandemic influenza A (H1N1) virus
Title | Anti-ganglioside antibodies were not detected in human subjects infected with or vaccinated against 2009 pandemic influenza A (H1N1) virus |
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Authors | |
Keywords | Ganglioside GM1 antibody Influenza vaccine 2009 H1N1 influenza Animal experiment Antibody detection |
Issue Date | 2012 |
Publisher | Elsevier Ltd. The Journal's web site is located at http://www.elsevier.com/locate/vaccine |
Citation | Vaccine, 2012, v. 30 n. 16, p. 2605-2610 How to Cite? |
Abstract | Recipients of influenza A (H1N1) vaccine in 1976 had an increased risk for the neurologic disorder Guillain-Barre syndrome (GBS). Anti-ganglioside antibodies, which might be associated with the development of GBS, were previously reported to be induced in mice immunized with an H1N1 vaccine of 1976 or another influenza vaccine. In this study we analyzed anti-ganglioside antibodies in human subjects infected with or vaccinated against 2009 pandemic H1N1, including eight patients diagnosed to have post-vaccination GBS. Antibodies against GM1 or another ganglioside were not detected in any subject or in vaccinated mice. Our results did not support the induction of anti-ganglioside antibodies by influenza viruses or vaccines. |
Persistent Identifier | http://hdl.handle.net/10722/163502 |
ISSN | 2023 Impact Factor: 4.5 2023 SCImago Journal Rankings: 1.342 |
ISI Accession Number ID | |
References |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Lei, T | en_US |
dc.contributor.author | Siu, KL | en_US |
dc.contributor.author | Kok, KH | en_US |
dc.contributor.author | Chan, KH | en_US |
dc.contributor.author | Chan, EYT | en_US |
dc.contributor.author | Hung, IFN | en_US |
dc.contributor.author | To, KKW | en_US |
dc.contributor.author | Li, PCK | en_US |
dc.contributor.author | Zhou, J | en_US |
dc.contributor.author | Zheng, BJ | en_US |
dc.contributor.author | Yuen, KY | en_US |
dc.contributor.author | Wang, M | en_US |
dc.contributor.author | Jin, DY | en_US |
dc.date.accessioned | 2012-09-05T05:32:33Z | - |
dc.date.available | 2012-09-05T05:32:33Z | - |
dc.date.issued | 2012 | en_US |
dc.identifier.citation | Vaccine, 2012, v. 30 n. 16, p. 2605-2610 | en_US |
dc.identifier.issn | 0264-410X | en_US |
dc.identifier.uri | http://hdl.handle.net/10722/163502 | - |
dc.description.abstract | Recipients of influenza A (H1N1) vaccine in 1976 had an increased risk for the neurologic disorder Guillain-Barre syndrome (GBS). Anti-ganglioside antibodies, which might be associated with the development of GBS, were previously reported to be induced in mice immunized with an H1N1 vaccine of 1976 or another influenza vaccine. In this study we analyzed anti-ganglioside antibodies in human subjects infected with or vaccinated against 2009 pandemic H1N1, including eight patients diagnosed to have post-vaccination GBS. Antibodies against GM1 or another ganglioside were not detected in any subject or in vaccinated mice. Our results did not support the induction of anti-ganglioside antibodies by influenza viruses or vaccines. | en_US |
dc.language | eng | en_US |
dc.publisher | Elsevier Ltd. The Journal's web site is located at http://www.elsevier.com/locate/vaccine | en_US |
dc.relation.ispartof | Vaccine | en_US |
dc.subject | Ganglioside GM1 antibody | en_US |
dc.subject | Influenza vaccine | en_US |
dc.subject | 2009 H1N1 influenza | en_US |
dc.subject | Animal experiment | en_US |
dc.subject | Antibody detection | - |
dc.title | Anti-ganglioside antibodies were not detected in human subjects infected with or vaccinated against 2009 pandemic influenza A (H1N1) virus | en_US |
dc.type | Article | en_US |
dc.identifier.email | Siu, KL: sklsfx@hkucc.hku.hk | en_US |
dc.identifier.email | Kok, KH: khkok@hku.hk | en_US |
dc.identifier.email | Chan, KH: chankh2@hkucc.hku.hk | - |
dc.identifier.email | Chan, EYT: eytchan@hkucc.hku.hk | - |
dc.identifier.email | Hung, IFN: ivanhung@hkucc.hku.hk | - |
dc.identifier.email | To, KKW: kelvinto@hkucc.hku.hk | - |
dc.identifier.email | Zhou, J: jiezhou@hku.hk | - |
dc.identifier.email | Zheng, BJ: bzheng@hkucc.hku.hk | - |
dc.identifier.email | Yuen, KY: kyyuen@hkucc.hku.hk | - |
dc.identifier.email | Jin, DY: dyjin@hku.hk | - |
dc.identifier.authority | Hung, IFN=rp00508 | en_US |
dc.identifier.authority | Jin, DY=rp00452 | en_US |
dc.description.nature | link_to_subscribed_fulltext | en_US |
dc.identifier.doi | 10.1016/j.vaccine.2012.02.009 | en_US |
dc.identifier.pmid | 22342549 | - |
dc.identifier.scopus | eid_2-s2.0-84862809138 | en_US |
dc.identifier.hkuros | 208363 | - |
dc.relation.references | http://www.scopus.com/mlt/select.url?eid=2-s2.0-84862809138&selection=ref&src=s&origin=recordpage | en_US |
dc.identifier.volume | 30 | en_US |
dc.identifier.issue | 16 | en_US |
dc.identifier.spage | 2605 | en_US |
dc.identifier.epage | 2610 | en_US |
dc.identifier.isi | WOS:000302663200001 | - |
dc.publisher.place | United Kingdom | en_US |
dc.identifier.scopusauthorid | Jin, DY=7201973614 | en_US |
dc.identifier.scopusauthorid | Wang, M=53265130500 | en_US |
dc.identifier.scopusauthorid | Yuen, KY=55018434500 | en_US |
dc.identifier.scopusauthorid | Zheng, BJ=54935584800 | en_US |
dc.identifier.scopusauthorid | Zhou, J=55262021600 | en_US |
dc.identifier.scopusauthorid | Li, PCK=55262189900 | en_US |
dc.identifier.scopusauthorid | To, KKW=55024912100 | en_US |
dc.identifier.scopusauthorid | Hung, IFN=7006103457 | en_US |
dc.identifier.scopusauthorid | Chan, EYT=55262166100 | en_US |
dc.identifier.scopusauthorid | Chan, KH=7406034307 | en_US |
dc.identifier.scopusauthorid | Kok, KH=55261897900 | en_US |
dc.identifier.scopusauthorid | Siu, KL=55261997500 | en_US |
dc.identifier.scopusauthorid | Lei, T=37000963500 | en_US |
dc.identifier.citeulike | 10366680 | - |
dc.identifier.issnl | 0264-410X | - |