Article: Correlation study between spot urine protein-to-creatinine ratio and 24-hour urine protein measurement in 174 patients for proteinuria assessment

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TitleCorrelation study between spot urine protein-to-creatinine ratio and 24-hour urine protein measurement in 174 patients for proteinuria assessment
AuthorsSiu, WK1 3
Mak, CM3 4
Lee, HCH3
Tam, S4
Lee, J4
Chan, TM2
Fung, KSS3
Tong, KLM3
Chan, YWA3
Keywords24-Hour Urine Protein
Proteinuria
Urine Protein-To-Creatinine Ratio
Issue Date2011
PublisherLippincott Williams & Wilkins Asia. The Journal's web site is located at http://www.hkjn.org/
CitationHong Kong Journal Of Nephrology, 2011, v. 13 n. 2, p. 51-54 [How to Cite?]
DOI: http://dx.doi.org/10.1016/j.hkjn.2011.09.003
AbstractBackground/Purpose: According to the US National Kidney Foundation K/DOQI Guidelines in 2000, under most circumstances, spot urine samples should be used to detect and monitor proteinuria in children and adults and timed collection is often unnecessary. However, its use is still not widely implemented in Hong Kong. We aimed to assess the correlation of spot urine protein-to-creatinine (Pr/Cr) ratio to 24-hour urine protein excretion in our local setting. Methods: This was a prospective study set in regional hospitals in Hong Kong. A total of 174 patients were recruited from 2007 to 2008. Spot urine Pr/Cr ratio and 24-hour urine protein measurements were determined. Linear regression model was used to fit and test the relationship between 24-hour urine protein excretion and the spot urine Pr/Cr ratio. Results: Spot urine Pr/Cr ratio correlated well with 24-hour urine protein excretion (r = 0.95, p < 0.0001). Conclusion: Spot urine Pr/Cr ratio is a convenient, user-friendly and reliable method to replace 24-hour urine protein measurement for the assessment of proteinuria. © 2011, Hong Kong Society of Nephrology Ltd. Published by Elsevier Taiwan LLC. All rights reserved.
ISSN1561-5413
2011 SCImago Journal Rankings: 0.031
DOIhttp://dx.doi.org/10.1016/j.hkjn.2011.09.003
ReferencesReferences in Scopus
DC Field
Value
dc.contributor.authorSiu, WK
dc.contributor.authorMak, CM
dc.contributor.authorLee, HCH
dc.contributor.authorTam, S
dc.contributor.authorLee, J
dc.contributor.authorChan, TM
dc.contributor.authorFung, KSS
dc.contributor.authorTong, KLM
dc.contributor.authorChan, YWA
dc.date.accessioned2012-09-05T05:31:05Z
dc.date.available2012-09-05T05:31:05Z
dc.date.issued2011
dc.description.abstractBackground/Purpose: According to the US National Kidney Foundation K/DOQI Guidelines in 2000, under most circumstances, spot urine samples should be used to detect and monitor proteinuria in children and adults and timed collection is often unnecessary. However, its use is still not widely implemented in Hong Kong. We aimed to assess the correlation of spot urine protein-to-creatinine (Pr/Cr) ratio to 24-hour urine protein excretion in our local setting. Methods: This was a prospective study set in regional hospitals in Hong Kong. A total of 174 patients were recruited from 2007 to 2008. Spot urine Pr/Cr ratio and 24-hour urine protein measurements were determined. Linear regression model was used to fit and test the relationship between 24-hour urine protein excretion and the spot urine Pr/Cr ratio. Results: Spot urine Pr/Cr ratio correlated well with 24-hour urine protein excretion (r = 0.95, p < 0.0001). Conclusion: Spot urine Pr/Cr ratio is a convenient, user-friendly and reliable method to replace 24-hour urine protein measurement for the assessment of proteinuria. © 2011, Hong Kong Society of Nephrology Ltd. Published by Elsevier Taiwan LLC. All rights reserved.
dc.description.natureLink_to_subscribed_fulltext
dc.identifier.citationHong Kong Journal Of Nephrology, 2011, v. 13 n. 2, p. 51-54 [How to Cite?]
DOI: http://dx.doi.org/10.1016/j.hkjn.2011.09.003
dc.identifier.doihttp://dx.doi.org/10.1016/j.hkjn.2011.09.003
dc.identifier.epage54
dc.identifier.issn1561-5413
2011 SCImago Journal Rankings: 0.031
dc.identifier.issue2
dc.identifier.scopuseid_2-s2.0-81155131701
dc.identifier.spage51
dc.identifier.urihttp://hdl.handle.net/10722/163414
dc.identifier.volume13
dc.languageeng
dc.publisherLippincott Williams & Wilkins Asia. The Journal's web site is located at http://www.hkjn.org/
dc.publisher.placeHong Kong
dc.relation.ispartofHong Kong Journal of Nephrology
dc.relation.referencesReferences in Scopus
dc.subject24-Hour Urine Protein
dc.subjectProteinuria
dc.subjectUrine Protein-To-Creatinine Ratio
dc.titleCorrelation study between spot urine protein-to-creatinine ratio and 24-hour urine protein measurement in 174 patients for proteinuria assessment
dc.typeArticle
Author Affiliations
  1. Tuen Mun Hospital
  2. The University of Hong Kong
  3. Princess Margaret Hospital Hong Kong
  4. Queen Mary Hospital Hong Kong