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Article: Correlation study between spot urine protein-to-creatinine ratio and 24-hour urine protein measurement in 174 patients for proteinuria assessment

TitleCorrelation study between spot urine protein-to-creatinine ratio and 24-hour urine protein measurement in 174 patients for proteinuria assessment
Authors
Keywords24-Hour Urine Protein
Proteinuria
Urine Protein-To-Creatinine Ratio
Issue Date2011
PublisherLippincott Williams & Wilkins Asia. The Journal's web site is located at http://www.hkjn.org/
Citation
Hong Kong Journal Of Nephrology, 2011, v. 13 n. 2, p. 51-54 How to Cite?
Abstract
Background/Purpose: According to the US National Kidney Foundation K/DOQI Guidelines in 2000, under most circumstances, spot urine samples should be used to detect and monitor proteinuria in children and adults and timed collection is often unnecessary. However, its use is still not widely implemented in Hong Kong. We aimed to assess the correlation of spot urine protein-to-creatinine (Pr/Cr) ratio to 24-hour urine protein excretion in our local setting. Methods: This was a prospective study set in regional hospitals in Hong Kong. A total of 174 patients were recruited from 2007 to 2008. Spot urine Pr/Cr ratio and 24-hour urine protein measurements were determined. Linear regression model was used to fit and test the relationship between 24-hour urine protein excretion and the spot urine Pr/Cr ratio. Results: Spot urine Pr/Cr ratio correlated well with 24-hour urine protein excretion (r = 0.95, p < 0.0001). Conclusion: Spot urine Pr/Cr ratio is a convenient, user-friendly and reliable method to replace 24-hour urine protein measurement for the assessment of proteinuria. © 2011, Hong Kong Society of Nephrology Ltd. Published by Elsevier Taiwan LLC. All rights reserved.
Persistent Identifierhttp://hdl.handle.net/10722/163414
ISSN
2013 SCImago Journal Rankings: 0.110
References

 

Author Affiliations
  1. The University of Hong Kong
  2. Princess Margaret Hospital Hong Kong
  3. Tuen Mun Hospital
  4. Queen Mary Hospital Hong Kong
DC FieldValueLanguage
dc.contributor.authorSiu, WKen_US
dc.contributor.authorMak, CMen_US
dc.contributor.authorLee, HCHen_US
dc.contributor.authorTam, Sen_US
dc.contributor.authorLee, Jen_US
dc.contributor.authorChan, TMen_US
dc.contributor.authorFung, KSSen_US
dc.contributor.authorTong, KLMen_US
dc.contributor.authorChan, YWAen_US
dc.date.accessioned2012-09-05T05:31:05Z-
dc.date.available2012-09-05T05:31:05Z-
dc.date.issued2011en_US
dc.identifier.citationHong Kong Journal Of Nephrology, 2011, v. 13 n. 2, p. 51-54en_US
dc.identifier.issn1561-5413en_US
dc.identifier.urihttp://hdl.handle.net/10722/163414-
dc.description.abstractBackground/Purpose: According to the US National Kidney Foundation K/DOQI Guidelines in 2000, under most circumstances, spot urine samples should be used to detect and monitor proteinuria in children and adults and timed collection is often unnecessary. However, its use is still not widely implemented in Hong Kong. We aimed to assess the correlation of spot urine protein-to-creatinine (Pr/Cr) ratio to 24-hour urine protein excretion in our local setting. Methods: This was a prospective study set in regional hospitals in Hong Kong. A total of 174 patients were recruited from 2007 to 2008. Spot urine Pr/Cr ratio and 24-hour urine protein measurements were determined. Linear regression model was used to fit and test the relationship between 24-hour urine protein excretion and the spot urine Pr/Cr ratio. Results: Spot urine Pr/Cr ratio correlated well with 24-hour urine protein excretion (r = 0.95, p < 0.0001). Conclusion: Spot urine Pr/Cr ratio is a convenient, user-friendly and reliable method to replace 24-hour urine protein measurement for the assessment of proteinuria. © 2011, Hong Kong Society of Nephrology Ltd. Published by Elsevier Taiwan LLC. All rights reserved.en_US
dc.languageengen_US
dc.publisherLippincott Williams & Wilkins Asia. The Journal's web site is located at http://www.hkjn.org/en_US
dc.relation.ispartofHong Kong Journal of Nephrologyen_US
dc.subject24-Hour Urine Proteinen_US
dc.subjectProteinuriaen_US
dc.subjectUrine Protein-To-Creatinine Ratioen_US
dc.titleCorrelation study between spot urine protein-to-creatinine ratio and 24-hour urine protein measurement in 174 patients for proteinuria assessmenten_US
dc.typeArticleen_US
dc.identifier.emailChan, TM:dtmchan@hku.hken_US
dc.identifier.authorityChan, TM=rp00394en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1016/j.hkjn.2011.09.003en_US
dc.identifier.scopuseid_2-s2.0-81155131701en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-81155131701&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume13en_US
dc.identifier.issue2en_US
dc.identifier.spage51en_US
dc.identifier.epage54en_US
dc.publisher.placeHong Kongen_US
dc.identifier.scopusauthoridSiu, WK=36194091800en_US
dc.identifier.scopusauthoridMak, CM=37052378200en_US
dc.identifier.scopusauthoridLee, HCH=24802335600en_US
dc.identifier.scopusauthoridTam, S=7202037323en_US
dc.identifier.scopusauthoridLee, J=7601479992en_US
dc.identifier.scopusauthoridChan, TM=7402687700en_US
dc.identifier.scopusauthoridFung, KSS=54415585800en_US
dc.identifier.scopusauthoridTong, KLM=55126325800en_US
dc.identifier.scopusauthoridChan, YWA=36989085300en_US

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