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Article: Correlation study between spot urine protein-to-creatinine ratio and 24-hour urine protein measurement in 174 patients for proteinuria assessment
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TitleCorrelation study between spot urine protein-to-creatinine ratio and 24-hour urine protein measurement in 174 patients for proteinuria assessment
 
AuthorsSiu, WK2 3
Mak, CM2 4
Lee, HCH2
Tam, S4
Lee, J4
Chan, TM1
Fung, KSS2
Tong, KLM2
Chan, YWA2
 
Keywords24-Hour Urine Protein
Proteinuria
Urine Protein-To-Creatinine Ratio
 
Issue Date2011
 
PublisherLippincott Williams & Wilkins Asia. The Journal's web site is located at http://www.hkjn.org/
 
CitationHong Kong Journal Of Nephrology, 2011, v. 13 n. 2, p. 51-54 [How to Cite?]
DOI: http://dx.doi.org/10.1016/j.hkjn.2011.09.003
 
AbstractBackground/Purpose: According to the US National Kidney Foundation K/DOQI Guidelines in 2000, under most circumstances, spot urine samples should be used to detect and monitor proteinuria in children and adults and timed collection is often unnecessary. However, its use is still not widely implemented in Hong Kong. We aimed to assess the correlation of spot urine protein-to-creatinine (Pr/Cr) ratio to 24-hour urine protein excretion in our local setting. Methods: This was a prospective study set in regional hospitals in Hong Kong. A total of 174 patients were recruited from 2007 to 2008. Spot urine Pr/Cr ratio and 24-hour urine protein measurements were determined. Linear regression model was used to fit and test the relationship between 24-hour urine protein excretion and the spot urine Pr/Cr ratio. Results: Spot urine Pr/Cr ratio correlated well with 24-hour urine protein excretion (r = 0.95, p < 0.0001). Conclusion: Spot urine Pr/Cr ratio is a convenient, user-friendly and reliable method to replace 24-hour urine protein measurement for the assessment of proteinuria. © 2011, Hong Kong Society of Nephrology Ltd. Published by Elsevier Taiwan LLC. All rights reserved.
 
ISSN1561-5413
2012 SCImago Journal Rankings: 0.162
 
DOIhttp://dx.doi.org/10.1016/j.hkjn.2011.09.003
 
ReferencesReferences in Scopus
 
DC FieldValue
dc.contributor.authorSiu, WK
 
dc.contributor.authorMak, CM
 
dc.contributor.authorLee, HCH
 
dc.contributor.authorTam, S
 
dc.contributor.authorLee, J
 
dc.contributor.authorChan, TM
 
dc.contributor.authorFung, KSS
 
dc.contributor.authorTong, KLM
 
dc.contributor.authorChan, YWA
 
dc.date.accessioned2012-09-05T05:31:05Z
 
dc.date.available2012-09-05T05:31:05Z
 
dc.date.issued2011
 
dc.description.abstractBackground/Purpose: According to the US National Kidney Foundation K/DOQI Guidelines in 2000, under most circumstances, spot urine samples should be used to detect and monitor proteinuria in children and adults and timed collection is often unnecessary. However, its use is still not widely implemented in Hong Kong. We aimed to assess the correlation of spot urine protein-to-creatinine (Pr/Cr) ratio to 24-hour urine protein excretion in our local setting. Methods: This was a prospective study set in regional hospitals in Hong Kong. A total of 174 patients were recruited from 2007 to 2008. Spot urine Pr/Cr ratio and 24-hour urine protein measurements were determined. Linear regression model was used to fit and test the relationship between 24-hour urine protein excretion and the spot urine Pr/Cr ratio. Results: Spot urine Pr/Cr ratio correlated well with 24-hour urine protein excretion (r = 0.95, p < 0.0001). Conclusion: Spot urine Pr/Cr ratio is a convenient, user-friendly and reliable method to replace 24-hour urine protein measurement for the assessment of proteinuria. © 2011, Hong Kong Society of Nephrology Ltd. Published by Elsevier Taiwan LLC. All rights reserved.
 
dc.description.natureLink_to_subscribed_fulltext
 
dc.identifier.citationHong Kong Journal Of Nephrology, 2011, v. 13 n. 2, p. 51-54 [How to Cite?]
DOI: http://dx.doi.org/10.1016/j.hkjn.2011.09.003
 
dc.identifier.doihttp://dx.doi.org/10.1016/j.hkjn.2011.09.003
 
dc.identifier.epage54
 
dc.identifier.issn1561-5413
2012 SCImago Journal Rankings: 0.162
 
dc.identifier.issue2
 
dc.identifier.scopuseid_2-s2.0-81155131701
 
dc.identifier.spage51
 
dc.identifier.urihttp://hdl.handle.net/10722/163414
 
dc.identifier.volume13
 
dc.languageeng
 
dc.publisherLippincott Williams & Wilkins Asia. The Journal's web site is located at http://www.hkjn.org/
 
dc.publisher.placeHong Kong
 
dc.relation.ispartofHong Kong Journal of Nephrology
 
dc.relation.referencesReferences in Scopus
 
dc.subject24-Hour Urine Protein
 
dc.subjectProteinuria
 
dc.subjectUrine Protein-To-Creatinine Ratio
 
dc.titleCorrelation study between spot urine protein-to-creatinine ratio and 24-hour urine protein measurement in 174 patients for proteinuria assessment
 
dc.typeArticle
 
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<contributor.author>Mak, CM</contributor.author>
<contributor.author>Lee, HCH</contributor.author>
<contributor.author>Tam, S</contributor.author>
<contributor.author>Lee, J</contributor.author>
<contributor.author>Chan, TM</contributor.author>
<contributor.author>Fung, KSS</contributor.author>
<contributor.author>Tong, KLM</contributor.author>
<contributor.author>Chan, YWA</contributor.author>
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<description.abstract>Background/Purpose: According to the US National Kidney Foundation K/DOQI Guidelines in 2000, under most circumstances, spot urine samples should be used to detect and monitor proteinuria in children and adults and timed collection is often unnecessary. However, its use is still not widely implemented in Hong Kong. We aimed to assess the correlation of spot urine protein-to-creatinine (Pr/Cr) ratio to 24-hour urine protein excretion in our local setting. Methods: This was a prospective study set in regional hospitals in Hong Kong. A total of 174 patients were recruited from 2007 to 2008. Spot urine Pr/Cr ratio and 24-hour urine protein measurements were determined. Linear regression model was used to fit and test the relationship between 24-hour urine protein excretion and the spot urine Pr/Cr ratio. Results: Spot urine Pr/Cr ratio correlated well with 24-hour urine protein excretion (r = 0.95, p &lt; 0.0001). Conclusion: Spot urine Pr/Cr ratio is a convenient, user-friendly and reliable method to replace 24-hour urine protein measurement for the assessment of proteinuria. &#169; 2011, Hong Kong Society of Nephrology Ltd. Published by Elsevier Taiwan LLC. All rights reserved.</description.abstract>
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Author Affiliations
  1. The University of Hong Kong
  2. Princess Margaret Hospital Hong Kong
  3. Tuen Mun Hospital
  4. Queen Mary Hospital Hong Kong