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Article: Combination therapy for chronic hepatitis B: Simultaneous or sequential?

TitleCombination therapy for chronic hepatitis B: Simultaneous or sequential?
Authors
Yuen, MFLai, CL
Issue Date2007
PublisherNature Publishing Group. The Journal's web site is located at http://www.nature.com/ajg/index.html
Citation
American Journal Of Gastroenterology, 2007, v. 102 n. 1, p. 105-106 How to Cite?
DOI: http://dx.doi.org/10.1111/j.1572-0241.2006.00997.x
AbstractVarious regimens of combination or sequential therapy using nucleoside/nucleotide analogues (NAs) and interferon-alfa (IFN-α) have been tried for the treatment of chronic hepatitis B. To date, combination therapy of two NAs and of IFN-α and NAs fails to achieve extra viral suppression. Sequential therapy with lamivudine followed by IFN-α seems to have better sustained virologic response. However, the long-term beneficial effect of using this approach remains to be defined. © 2007 by Am. Coll. of Gastroenterology.
Persistent Identifierhttp://hdl.handle.net/10722/163054
ISSN
0002-9270
2023 Impact Factor: 8.0
2023 SCImago Journal Rankings: 2.391
ISI Accession Number ID
WOS:000243376500017
References
References in Scopus

 

DC FieldValueLanguage
dc.contributor.authorYuen, MFen_US
dc.contributor.authorLai, CLen_US
dc.date.accessioned2012-09-05T05:27:00Z-
dc.date.available2012-09-05T05:27:00Z-
dc.date.issued2007en_US
dc.identifier.citationAmerican Journal Of Gastroenterology, 2007, v. 102 n. 1, p. 105-106en_US
dc.identifier.issn0002-9270en_US
dc.identifier.urihttp://hdl.handle.net/10722/163054-
dc.description.abstractVarious regimens of combination or sequential therapy using nucleoside/nucleotide analogues (NAs) and interferon-alfa (IFN-α) have been tried for the treatment of chronic hepatitis B. To date, combination therapy of two NAs and of IFN-α and NAs fails to achieve extra viral suppression. Sequential therapy with lamivudine followed by IFN-α seems to have better sustained virologic response. However, the long-term beneficial effect of using this approach remains to be defined. © 2007 by Am. Coll. of Gastroenterology.en_US
dc.languageengen_US
dc.publisherNature Publishing Group. The Journal's web site is located at http://www.nature.com/ajg/index.htmlen_US
dc.relation.ispartofAmerican Journal of Gastroenterologyen_US
dc.subject.meshAntiviral Agents - Therapeutic Useen_US
dc.subject.meshDna, Viral - Analysis - Drug Effectsen_US
dc.subject.meshDrug Resistanceen_US
dc.subject.meshDrug Therapy, Combinationen_US
dc.subject.meshHepatitis B, Chronic - Drug Therapyen_US
dc.subject.meshHumansen_US
dc.subject.meshInterferon-Alpha - Therapeutic Useen_US
dc.subject.meshLamivudine - Therapeutic Useen_US
dc.subject.meshRecombinant Proteinsen_US
dc.subject.meshViral Loaden_US
dc.titleCombination therapy for chronic hepatitis B: Simultaneous or sequential?en_US
dc.typeArticleen_US
dc.identifier.emailYuen, MF:mfyuen@hkucc.hku.hken_US
dc.identifier.emailLai, CL:hrmelcl@hku.hken_US
dc.identifier.authorityYuen, MF=rp00479en_US
dc.identifier.authorityLai, CL=rp00314en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1111/j.1572-0241.2006.00997.xen_US
dc.identifier.pmid17266690-
dc.identifier.scopuseid_2-s2.0-33846053592en_US
dc.identifier.hkuros130670-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-33846053592&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume102en_US
dc.identifier.issue1en_US
dc.identifier.spage105en_US
dc.identifier.epage106en_US
dc.identifier.isiWOS:000243376500017-
dc.publisher.placeUnited Statesen_US
dc.identifier.scopusauthoridYuen, MF=7102031955en_US
dc.identifier.scopusauthoridLai, CL=7403086396en_US
dc.identifier.citeulike1033272-
dc.identifier.issnl0002-9270-

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